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For: Régnier CH, Song HY, Gao X, Goeddel DV, Cao Z, Rothe M. Identification and characterization of an IkappaB kinase. Cell. 1997;90:373-383. [PMID: 9244310 DOI: 10.1016/s0092-8674(00)80344-x] [Cited by in Crossref: 919] [Cited by in F6Publishing: 244] [Article Influence: 36.8] [Reference Citation Analysis]
Number Citing Articles
1 Bhakar AL, Tannis LL, Zeindler C, Russo MP, Jobin C, Park DS, MacPherson S, Barker PA. Constitutive nuclear factor-kappa B activity is required for central neuron survival. J Neurosci 2002;22:8466-75. [PMID: 12351721 [PMID: 12351721 DOI: 10.1523/jneurosci.22-19-08466.2002] [Cited by in Crossref: 233] [Article Influence: 11.7] [Reference Citation Analysis]
2 Shen C, Zhao XL, Ju W, Zou XB, Huo LR, Yan W, Zou JH, Yan GD, Jenkins EC, Brown WT, Zhong N. A proteomic investigation of B lymphocytes in an autistic family: a pilot study of exposure to natural rubber latex (NRL) may lead to autism. J Mol Neurosci 2011;43:443-52. [PMID: 20957522 DOI: 10.1007/s12031-010-9463-5] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 0.8] [Reference Citation Analysis]
3 Li Q, Harraz MM, Zhou W, Zhang LN, Ding W, Zhang Y, Eggleston T, Yeaman C, Banfi B, Engelhardt JF. Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes. Mol Cell Biol. 2006;26:140-154. [PMID: 16354686 DOI: 10.1128/mcb.26.1.140-154.2006] [Cited by in Crossref: 177] [Cited by in F6Publishing: 105] [Article Influence: 11.1] [Reference Citation Analysis]
4 He B, Raab-Traub N, Casali P, Cerutti A. EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching. J Immunol 2003;171:5215-24. [PMID: 14607922 DOI: 10.4049/jimmunol.171.10.5215] [Cited by in Crossref: 169] [Cited by in F6Publishing: 152] [Article Influence: 9.4] [Reference Citation Analysis]
5 Baud V, Liu ZG, Bennett B, Suzuki N, Xia Y, Karin M. Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. Genes Dev 1999;13:1297-308. [PMID: 10346818 DOI: 10.1101/gad.13.10.1297] [Cited by in Crossref: 342] [Cited by in F6Publishing: 335] [Article Influence: 14.9] [Reference Citation Analysis]
6 Coope HJ, Atkinson PG, Huhse B, Belich M, Janzen J, Holman MJ, Klaus GG, Johnston LH, Ley SC. CD40 regulates the processing of NF-kappaB2 p100 to p52. EMBO J 2002;21:5375-85. [PMID: 12374738 DOI: 10.1093/emboj/cdf542] [Cited by in Crossref: 324] [Cited by in F6Publishing: 320] [Article Influence: 16.2] [Reference Citation Analysis]
7 Kaufman CK, Fuchs E. It's got you covered. NF-kappaB in the epidermis. J Cell Biol 2000;149:999-1004. [PMID: 10831603 DOI: 10.1083/jcb.149.5.999] [Cited by in Crossref: 95] [Cited by in F6Publishing: 86] [Article Influence: 4.3] [Reference Citation Analysis]
8 Purcell NH, Tang G, Yu C, Mercurio F, DiDonato JA, Lin A. Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proc Natl Acad Sci U S A 2001;98:6668-73. [PMID: 11381115 DOI: 10.1073/pnas.111155798] [Cited by in Crossref: 243] [Cited by in F6Publishing: 235] [Article Influence: 11.6] [Reference Citation Analysis]
9 Neurath MF, Becker C, Barbulescu K. Role of NF-kappaB in immune and inflammatory responses in the gut. Gut. 1998;43:856-860. [PMID: 9824616 DOI: 10.1136/gut.43.6.856] [Cited by in Crossref: 235] [Cited by in F6Publishing: 229] [Article Influence: 10.2] [Reference Citation Analysis]
10 Marinari B, Costanzo A, Marzano V, Piccolella E, Tuosto L. CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters. Proc Natl Acad Sci U S A 2004;101:6098-103. [PMID: 15079071 DOI: 10.1073/pnas.0308688101] [Cited by in Crossref: 59] [Cited by in F6Publishing: 58] [Article Influence: 3.3] [Reference Citation Analysis]
11 Devin A, Lin Y, Yamaoka S, Li Z, Karin M, Liu Zg. The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF. Mol Cell Biol 2001;21:3986-94. [PMID: 11359906 DOI: 10.1128/MCB.21.12.3986-3994.2001] [Cited by in Crossref: 105] [Cited by in F6Publishing: 38] [Article Influence: 5.0] [Reference Citation Analysis]
12 Park GY, Wang X, Hu N, Pedchenko TV, Blackwell TS, Christman JW. NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKalpha. J Biol Chem 2006;281:18684-90. [PMID: 16675465 DOI: 10.1074/jbc.M600733200] [Cited by in Crossref: 38] [Cited by in F6Publishing: 20] [Article Influence: 2.4] [Reference Citation Analysis]
13 Ryzhakov G, Randow F. SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK. EMBO J 2007;26:3180-90. [PMID: 17568778 DOI: 10.1038/sj.emboj.7601743] [Cited by in Crossref: 136] [Cited by in F6Publishing: 132] [Article Influence: 9.1] [Reference Citation Analysis]
14 Lin B, Xu D, Leaman DW. X-linked inhibitor of apoptosis-associated factor 1 regulates TNF receptor 1 complex stability. FEBS Lett 2016;590:4381-92. [PMID: 27768232 DOI: 10.1002/1873-3468.12467] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.5] [Reference Citation Analysis]
15 Karin M, Delhase M. JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action? Proc Natl Acad Sci U S A 1998;95:9067-9. [PMID: 9689033 DOI: 10.1073/pnas.95.16.9067] [Cited by in Crossref: 166] [Cited by in F6Publishing: 165] [Article Influence: 6.9] [Reference Citation Analysis]
16 Attar RM, Macdonald-Bravo H, Raventos-Suarez C, Durham SK, Bravo R. Expression of constitutively active IkappaB beta in T cells of transgenic mice: persistent NF-kappaB activity is required for T-cell immune responses. Mol Cell Biol 1998;18:477-87. [PMID: 9418895 DOI: 10.1128/MCB.18.1.477] [Cited by in Crossref: 34] [Cited by in F6Publishing: 8] [Article Influence: 1.4] [Reference Citation Analysis]
17 Jensen LE, Whitehead AS. Regulation of serum amyloid A protein expression during the acute-phase response. Biochem J. 1998;334:489-503. [PMID: 9729453 DOI: 10.1042/bj3340489] [Cited by in Crossref: 270] [Cited by in F6Publishing: 265] [Article Influence: 11.3] [Reference Citation Analysis]
18 O'Mahony A, Lin X, Geleziunas R, Greene WC. Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions. Mol Cell Biol 2000;20:1170-8. [PMID: 10648602 DOI: 10.1128/MCB.20.4.1170-1178.2000] [Cited by in Crossref: 88] [Cited by in F6Publishing: 36] [Article Influence: 4.0] [Reference Citation Analysis]
19 Humphries F, Yang S, Wang B, Moynagh PN. RIP kinases: key decision makers in cell death and innate immunity. Cell Death Differ 2015;22:225-36. [PMID: 25146926 DOI: 10.1038/cdd.2014.126] [Cited by in Crossref: 123] [Cited by in F6Publishing: 121] [Article Influence: 15.4] [Reference Citation Analysis]
20 Yeung KC, Rose DW, Dhillon AS, Yaros D, Gustafsson M, Chatterjee D, McFerran B, Wyche J, Kolch W, Sedivy JM. Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation. Mol Cell Biol. 2001;21:7207-7217. [PMID: 11585904 DOI: 10.1128/MCB.21.21.7207-7217.2001] [Cited by in Crossref: 271] [Cited by in F6Publishing: 133] [Article Influence: 12.9] [Reference Citation Analysis]
21 Baumann B, Weber CK, Troppmair J, Whiteside S, Israel A, Rapp UR, Wirth T. Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation. Proc Natl Acad Sci U S A 2000;97:4615-20. [PMID: 10758165 DOI: 10.1073/pnas.080583397] [Cited by in Crossref: 116] [Cited by in F6Publishing: 116] [Article Influence: 5.3] [Reference Citation Analysis]
22 Winston JT, Strack P, Beer-Romero P, Chu CY, Elledge SJ, Harper JW. The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro. Genes Dev 1999;13:270-83. [PMID: 9990852 DOI: 10.1101/gad.13.3.270] [Cited by in F6Publishing: 665] [Reference Citation Analysis]
23 Hayden MS, Ghosh S. Regulation of NF-κB by TNF family cytokines. Semin Immunol 2014;26:253-66. [PMID: 24958609 DOI: 10.1016/j.smim.2014.05.004] [Cited by in Crossref: 351] [Cited by in F6Publishing: 349] [Article Influence: 43.9] [Reference Citation Analysis]
24 Qian Y, Zhao Z, Jiang Z, Li X. Role of NF kappa B activator Act1 in CD40-mediated signaling in epithelial cells. Proc Natl Acad Sci U S A 2002;99:9386-91. [PMID: 12089335 DOI: 10.1073/pnas.142294499] [Cited by in Crossref: 50] [Cited by in F6Publishing: 48] [Article Influence: 2.5] [Reference Citation Analysis]
25 Cerutti A, Kim EC, Shah S, Schattner EJ, Zan H, Schaffer A, Casali P. Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells. Nat Immunol 2001;2:150-6. [PMID: 11175813 DOI: 10.1038/84254] [Cited by in Crossref: 35] [Cited by in F6Publishing: 34] [Article Influence: 1.7] [Reference Citation Analysis]
26 Bloor S, Ryzhakov G, Wagner S, Butler PJ, Smith DL, Krumbach R, Dikic I, Randow F. Signal processing by its coil zipper domain activates IKK gamma. Proc Natl Acad Sci U S A 2008;105:1279-84. [PMID: 18216269 DOI: 10.1073/pnas.0706552105] [Cited by in Crossref: 50] [Cited by in F6Publishing: 49] [Article Influence: 3.6] [Reference Citation Analysis]
27 Kim S, La Motte-Mohs RN, Rudolph D, Zuniga-Pflucker JC, Mak TW. The role of nuclear factor-kappaB essential modulator (NEMO) in B cell development and survival. Proc Natl Acad Sci U S A 2003;100:1203-8. [PMID: 12538858 DOI: 10.1073/pnas.0337707100] [Cited by in Crossref: 29] [Cited by in F6Publishing: 27] [Article Influence: 1.5] [Reference Citation Analysis]
28 Batra S, Balamayooran G, Sahoo MK. Nuclear factor-κB: a key regulator in health and disease of lungs. Arch Immunol Ther Exp (Warsz) 2011;59:335-51. [PMID: 21786215 DOI: 10.1007/s00005-011-0136-z] [Cited by in Crossref: 30] [Cited by in F6Publishing: 35] [Article Influence: 2.7] [Reference Citation Analysis]
29 Sclabas GM, Fujioka S, Schmidt C, Evans DB, Chiao PJ. NF-kappaB in pancreatic cancer. Int J Gastrointest Cancer 2003;33:15-26. [PMID: 12909735 DOI: 10.1385/IJGC:33:1:15] [Cited by in Crossref: 36] [Cited by in F6Publishing: 23] [Article Influence: 2.0] [Reference Citation Analysis]
30 Tagoug I, Sauty De Chalon A, Dumontet C. Inhibition of IGF-1 signalling enhances the apoptotic effect of AS602868, an IKK2 inhibitor, in multiple myeloma cell lines. PLoS One 2011;6:e22641. [PMID: 21799925 DOI: 10.1371/journal.pone.0022641] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 1.2] [Reference Citation Analysis]
31 Hirata Y, Maeda S, Ohmae T, Shibata W, Yanai A, Ogura K, Yoshida H, Kawabe T, Omata M. Helicobacter pylori induces IkappaB kinase alpha nuclear translocation and chemokine production in gastric epithelial cells. Infect Immun 2006;74:1452-61. [PMID: 16495515 DOI: 10.1128/IAI.74.3.1452-1461.2006] [Cited by in Crossref: 33] [Cited by in F6Publishing: 17] [Article Influence: 2.1] [Reference Citation Analysis]
32 Muzio M, Natoli G, Saccani S, Levrero M, Mantovani A. The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6). J Exp Med 1998;187:2097-101. [PMID: 9625770 DOI: 10.1084/jem.187.12.2097] [Cited by in Crossref: 446] [Cited by in F6Publishing: 425] [Article Influence: 18.6] [Reference Citation Analysis]
33 Guttridge DC, Albanese C, Reuther JY, Pestell RG, Baldwin AS Jr. NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol Cell Biol 1999;19:5785-99. [PMID: 10409765 DOI: 10.1128/MCB.19.8.5785] [Cited by in Crossref: 970] [Cited by in F6Publishing: 410] [Article Influence: 42.2] [Reference Citation Analysis]
34 Schwandner R, Yamaguchi K, Cao Z. Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction. J Exp Med 2000;191:1233-40. [PMID: 10748240 DOI: 10.1084/jem.191.7.1233] [Cited by in Crossref: 237] [Cited by in F6Publishing: 236] [Article Influence: 10.8] [Reference Citation Analysis]
35 Shirakawa J, Kulkarni RN. Novel factors modulating human β-cell proliferation. Diabetes Obes Metab 2016;18 Suppl 1:71-7. [PMID: 27615134 DOI: 10.1111/dom.12731] [Cited by in Crossref: 25] [Cited by in F6Publishing: 23] [Article Influence: 5.0] [Reference Citation Analysis]
36 Achoui M, Heyninck K, Looi CY, Mustafa AM, Haegeman G, Mustafa MR. Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs: involvement of MAPK and NF-κB pathways. Drug Des Devel Ther 2014;8:1993-2007. [PMID: 25349474 DOI: 10.2147/DDDT.S68659] [Reference Citation Analysis]
37 Ginzburg S, Golovine KV, Makhov PB, Uzzo RG, Kutikov A, Kolenko VM. Piperlongumine inhibits NF-κB activity and attenuates aggressive growth characteristics of prostate cancer cells. Prostate 2014;74:177-86. [PMID: 24151226 DOI: 10.1002/pros.22739] [Cited by in Crossref: 54] [Cited by in F6Publishing: 48] [Article Influence: 6.0] [Reference Citation Analysis]
38 Silverman N, Zhou R, Stöven S, Pandey N, Hultmark D, Maniatis T. A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity. Genes Dev 2000;14:2461-71. [PMID: 11018014 DOI: 10.1101/gad.817800] [Cited by in Crossref: 224] [Cited by in F6Publishing: 217] [Article Influence: 10.2] [Reference Citation Analysis]
39 Darwech I, Otero J, Alhawagri M, Dai S, Abu-Amer Y. Impediment of NEMO oligomerization inhibits osteoclastogenesis and osteolysis. J Cell Biochem 2009;108:1337-45. [PMID: 19830703 DOI: 10.1002/jcb.22364] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 1.3] [Reference Citation Analysis]
40 Liu F, Xia Y, Parker AS, Verma IM. IKK biology. Immunol Rev 2012;246:239-53. [PMID: 22435559 DOI: 10.1111/j.1600-065X.2012.01107.x] [Cited by in Crossref: 144] [Cited by in F6Publishing: 90] [Article Influence: 14.4] [Reference Citation Analysis]
41 Liu WK, Yen PF, Chien CY, Fann MJ, Su JY, Chou CK. The inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappaB and potentiate apoptosis. Biochem J 2004;378:867-76. [PMID: 14653779 DOI: 10.1042/BJ20031736] [Cited by in Crossref: 27] [Cited by in F6Publishing: 27] [Article Influence: 1.5] [Reference Citation Analysis]
42 Lim KH, Ancrile BB, Kashatus DF, Counter CM. Tumour maintenance is mediated by eNOS. Nature 2008;452:646-9. [PMID: 18344980 DOI: 10.1038/nature06778] [Cited by in Crossref: 233] [Cited by in F6Publishing: 201] [Article Influence: 16.6] [Reference Citation Analysis]
43 Shiao YJ, Lin YL, Sun YH, Chi CW, Chen CF, Wang CN. Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes. Br J Pharmacol 2005;144:42-51. [PMID: 15644867 DOI: 10.1038/sj.bjp.0706022] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 0.8] [Reference Citation Analysis]
44 He YT, Liu DW, Ding LY, Li Q, Xiao YH. Therapeutic effects and molecular mechanisms of anti-fibrosis herbs and selenium on rats with hepatic fibrosis. World J Gastroenterol 2004; 10(5): 703-706 [PMID: 14991942 DOI: 10.3748/wjg.v10.i5.703] [Cited by in CrossRef: 13] [Cited by in F6Publishing: 13] [Article Influence: 0.7] [Reference Citation Analysis]
45 Abu-Amer Y. Inflammation, cancer, and bone loss. Curr Opin Pharmacol 2009;9:427-33. [PMID: 19577517 DOI: 10.1016/j.coph.2009.06.007] [Cited by in Crossref: 22] [Cited by in F6Publishing: 19] [Article Influence: 1.7] [Reference Citation Analysis]
46 MacPartlin M, Zeng SX, Lu H. Phosphorylation and stabilization of TAp63gamma by IkappaB kinase-beta. J Biol Chem 2008;283:15754-61. [PMID: 18411264 DOI: 10.1074/jbc.M801394200] [Cited by in Crossref: 17] [Cited by in F6Publishing: 13] [Article Influence: 1.2] [Reference Citation Analysis]
47 Xu G, Tan X, Wang H, Sun W, Shi Y, Burlingame S, Gu X, Cao G, Zhang T, Qin J, Yang J. Ubiquitin-specific peptidase 21 inhibits tumor necrosis factor alpha-induced nuclear factor kappaB activation via binding to and deubiquitinating receptor-interacting protein 1. J Biol Chem 2010;285:969-78. [PMID: 19910467 DOI: 10.1074/jbc.M109.042689] [Cited by in Crossref: 82] [Cited by in F6Publishing: 55] [Article Influence: 6.3] [Reference Citation Analysis]
48 Reuther JY, Reuther GW, Cortez D, Pendergast AM, Baldwin AS. A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation. Genes Dev. 1998;12:968-981. [PMID: 9531535 DOI: 10.1101/gad.12.7.968] [Cited by in Crossref: 272] [Cited by in F6Publishing: 266] [Article Influence: 11.3] [Reference Citation Analysis]
49 Zollner TM, Podda M, Pien C, Elliott PJ, Kaufmann R, Boehncke WH. Proteasome inhibition reduces superantigen-mediated T cell activation and the severity of psoriasis in a SCID-hu model. J Clin Invest 2002;109:671-9. [PMID: 11877475 DOI: 10.1172/JCI12736] [Cited by in F6Publishing: 19] [Reference Citation Analysis]
50 Ghosh S. Regulation of inducible gene expression by the transcription factor NF-kappaB. Immunol Res. 1999;19:183-189. [PMID: 10493172 DOI: 10.1007/bf02786486] [Cited by in Crossref: 100] [Cited by in F6Publishing: 29] [Article Influence: 4.3] [Reference Citation Analysis]
51 Makris C, Roberts JL, Karin M. The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation. Mol Cell Biol 2002;22:6573-81. [PMID: 12192055 DOI: 10.1128/MCB.22.18.6573-6581.2002] [Cited by in Crossref: 63] [Cited by in F6Publishing: 28] [Article Influence: 3.2] [Reference Citation Analysis]
52 Jin R, Yamashita H, Yu X, Wang J, Franco OE, Wang Y, Hayward SW, Matusik RJ. Inhibition of NF-kappa B signaling restores responsiveness of castrate-resistant prostate cancer cells to anti-androgen treatment by decreasing androgen receptor-variant expression. Oncogene 2015;34:3700-10. [PMID: 25220414 DOI: 10.1038/onc.2014.302] [Cited by in Crossref: 52] [Cited by in F6Publishing: 49] [Article Influence: 6.5] [Reference Citation Analysis]
53 Steinhardt JJ, Gartenhaus RB. Promising personalized therapeutic options for diffuse large B-cell Lymphoma Subtypes with oncogene addictions. Clin Cancer Res 2012;18:4538-48. [PMID: 22745106 DOI: 10.1158/1078-0432.CCR-12-0217] [Cited by in Crossref: 8] [Cited by in F6Publishing: 5] [Article Influence: 0.8] [Reference Citation Analysis]
54 Luedde T, Assmus U, Wüstefeld T, Meyer zu Vilsendorf A, Roskams T, Schmidt-Supprian M, Rajewsky K, Brenner DA, Manns MP, Pasparakis M, Trautwein C. Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury. J Clin Invest 2005;115:849-59. [PMID: 15776110 DOI: 10.1172/JCI23493] [Cited by in F6Publishing: 53] [Reference Citation Analysis]
55 Delhase M. Positive and Negative Regulation of IB Kinase Activity Through IKK Subunit Phosphorylation. Science;284:309-13. [DOI: 10.1126/science.284.5412.309] [Cited by in Crossref: 665] [Cited by in F6Publishing: 649] [Article Influence: 28.9] [Reference Citation Analysis]
56 Sato T, Kotake D, Hiratsuka M, Hirasawa N. Enhancement of inflammatory protein expression and nuclear factor Κb (NF-Κb) activity by trichostatin A (TSA) in OP9 preadipocytes. PLoS One 2013;8:e59702. [PMID: 23555753 DOI: 10.1371/journal.pone.0059702] [Cited by in Crossref: 10] [Cited by in F6Publishing: 11] [Article Influence: 1.1] [Reference Citation Analysis]
57 Jeay S, Pianetti S, Kagan HM, Sonenshein GE. Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B. Mol Cell Biol 2003;23:2251-63. [PMID: 12640111 DOI: 10.1128/MCB.23.7.2251-2263.2003] [Cited by in Crossref: 81] [Cited by in F6Publishing: 38] [Article Influence: 4.3] [Reference Citation Analysis]
58 Höllsberg P. Mechanisms of T-cell activation by human T-cell lymphotropic virus type I. Microbiol Mol Biol Rev 1999;63:308-33. [PMID: 10357853 DOI: 10.1128/MMBR.63.2.308-333.1999] [Cited by in Crossref: 87] [Cited by in F6Publishing: 32] [Article Influence: 3.8] [Reference Citation Analysis]
59 Ashburner BP, Westerheide SD, Baldwin AS Jr. The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol 2001;21:7065-77. [PMID: 11564889 DOI: 10.1128/MCB.21.20.7065-7077.2001] [Cited by in Crossref: 538] [Cited by in F6Publishing: 256] [Article Influence: 25.6] [Reference Citation Analysis]
60 Ivins FJ, Montgomery MG, Smith SJ, Morris-Davies AC, Taylor IA, Rittinger K. NEMO oligomerization and its ubiquitin-binding properties. Biochem J 2009;421:243-51. [PMID: 19422324 DOI: 10.1042/BJ20090427] [Cited by in Crossref: 44] [Cited by in F6Publishing: 28] [Article Influence: 3.4] [Reference Citation Analysis]
61 Haseeb A, Chen D, Haqqi TM. Delphinidin inhibits IL-1β-induced activation of NF-κB by modulating the phosphorylation of IRAK-1(Ser376) in human articular chondrocytes. Rheumatology (Oxford) 2013;52:998-1008. [PMID: 23392593 DOI: 10.1093/rheumatology/kes363] [Cited by in Crossref: 49] [Cited by in F6Publishing: 49] [Article Influence: 5.4] [Reference Citation Analysis]
62 Chen LC, Lee WS. Estradiol reduces ferrous citrate complex-induced NOS2 up-regulation in cerebral endothelial cells by interfering the nuclear factor kappa B transactivation through an estrogen receptor β-mediated pathway. PLoS One 2013;8:e84320. [PMID: 24376801 DOI: 10.1371/journal.pone.0084320] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.3] [Reference Citation Analysis]
63 Li ZW, Chu W, Hu Y, Delhase M, Deerinck T, Ellisman M, Johnson R, Karin M. The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J Exp Med 1999;189:1839-45. [PMID: 10359587 DOI: 10.1084/jem.189.11.1839] [Cited by in Crossref: 685] [Cited by in F6Publishing: 670] [Article Influence: 29.8] [Reference Citation Analysis]
64 Sun W, Yu Y, Dotti G, Shen T, Tan X, Savoldo B, Pass AK, Chu M, Zhang D, Lu X, Fu S, Lin X, Yang J. PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation. Cell Signal 2009;21:95-102. [PMID: 18930133 DOI: 10.1016/j.cellsig.2008.09.012] [Cited by in Crossref: 69] [Cited by in F6Publishing: 69] [Article Influence: 4.9] [Reference Citation Analysis]
65 Napetschnig J, Wu H. Molecular basis of NF-κB signaling. Annu Rev Biophys 2013;42:443-68. [PMID: 23495970 DOI: 10.1146/annurev-biophys-083012-130338] [Cited by in Crossref: 512] [Cited by in F6Publishing: 493] [Article Influence: 56.9] [Reference Citation Analysis]
66 Leonardi A, Chariot A, Claudio E, Cunningham K, Siebenlist U. CIKS, a connection to Ikappa B kinase and stress-activated protein kinase. Proc Natl Acad Sci U S A 2000;97:10494-9. [PMID: 10962033 DOI: 10.1073/pnas.190245697] [Cited by in Crossref: 125] [Cited by in F6Publishing: 122] [Article Influence: 5.7] [Reference Citation Analysis]
67 Kaltschmidt B, Uherek M, Wellmann H, Volk B, Kaltschmidt C. Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis. Proc Natl Acad Sci U S A 1999;96:9409-14. [PMID: 10430956 DOI: 10.1073/pnas.96.16.9409] [Cited by in Crossref: 210] [Cited by in F6Publishing: 221] [Article Influence: 9.1] [Reference Citation Analysis]
68 Ferrari D, Wesselborg S, Bauer MK, Schulze-Osthoff K. Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65. J Cell Biol 1997;139:1635-43. [PMID: 9412459 DOI: 10.1083/jcb.139.7.1635] [Cited by in Crossref: 215] [Cited by in F6Publishing: 215] [Article Influence: 9.0] [Reference Citation Analysis]
69 Ogasa M, Miyazaki Y, Hiraoka S, Kitamura S, Nagasawa Y, Kishida O, Miyazaki T, Kiyohara T, Shinomura Y, Matsuzawa Y. Gastrin activates nuclear factor kappaB (NFkappaB) through a protein kinase C dependent pathway involving NFkappaB inducing kinase, inhibitor kappaB (IkappaB) kinase, and tumour necrosis factor receptor associated factor 6 (TRAF6) in MKN-28 cells transfected with gastrin receptor. Gut 2003;52:813-9. [PMID: 12740336 DOI: 10.1136/gut.52.6.813] [Cited by in Crossref: 24] [Cited by in F6Publishing: 25] [Article Influence: 1.3] [Reference Citation Analysis]
70 Nemoto S, DiDonato JA, Lin A. Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase. Mol Cell Biol 1998;18:7336-43. [PMID: 9819420 DOI: 10.1128/MCB.18.12.7336] [Cited by in Crossref: 181] [Cited by in F6Publishing: 49] [Article Influence: 7.5] [Reference Citation Analysis]
71 Zamanian-Daryoush M, Mogensen TH, DiDonato JA, Williams BR. NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase. Mol Cell Biol 2000;20:1278-90. [PMID: 10648614 DOI: 10.1128/MCB.20.4.1278-1290.2000] [Cited by in Crossref: 257] [Cited by in F6Publishing: 122] [Article Influence: 11.7] [Reference Citation Analysis]
72 Parvatiyar K, Pindado J, Dev A, Aliyari SR, Zaver SA, Gerami H, Chapon M, Ghaffari AA, Dhingra A, Cheng G. A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling. Nat Commun 2018;9:2770. [PMID: 30018345 DOI: 10.1038/s41467-018-05168-7] [Cited by in Crossref: 19] [Cited by in F6Publishing: 18] [Article Influence: 4.8] [Reference Citation Analysis]
73 Chen K, Qiu P, Yuan Y, Zheng L, He J, Wang C, Guo Q, Kenny J, Liu Q, Zhao J, Chen J, Tickner J, Fan S, Lin X, Xu J. Pseurotin A Inhibits Osteoclastogenesis and Prevents Ovariectomized-Induced Bone Loss by Suppressing Reactive Oxygen Species. Theranostics 2019;9:1634-50. [PMID: 31037128 DOI: 10.7150/thno.30206] [Cited by in Crossref: 49] [Cited by in F6Publishing: 51] [Article Influence: 16.3] [Reference Citation Analysis]
74 Zhou-Stache J, Buettner R, Artmann G, Mittermayer C, Bosserhoff AK. Inhibition of TNF-alpha induced cell death in human umbilical vein endothelial cells and Jurkat cells by protocatechuic acid. Med Biol Eng Comput. 2002;40:698-703. [PMID: 12507320 DOI: 10.1007/bf02345308] [Cited by in Crossref: 12] [Cited by in F6Publishing: 7] [Article Influence: 0.6] [Reference Citation Analysis]
75 Dhawan P, Richmond A. A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells. J Biol Chem 2002;277:7920-8. [PMID: 11773061 DOI: 10.1074/jbc.M112210200] [Cited by in Crossref: 202] [Cited by in F6Publishing: 98] [Article Influence: 9.6] [Reference Citation Analysis]
76 Huang WC, Ju TK, Hung MC, Chen CC. Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB. Mol Cell 2007;26:75-87. [PMID: 17434128 DOI: 10.1016/j.molcel.2007.02.019] [Cited by in Crossref: 183] [Cited by in F6Publishing: 187] [Article Influence: 12.2] [Reference Citation Analysis]
77 Sun W, Wang H, Zhao X, Yu Y, Fan Y, Wang H, Wang X, Lu X, Zhang G, Fu S, Yang J. Protein phosphatase 2A acts as a mitogen-activated protein kinase kinase kinase 3 (MEKK3) phosphatase to inhibit lysophosphatidic acid-induced IkappaB kinase beta/nuclear factor-kappaB activation. J Biol Chem 2010;285:21341-8. [PMID: 20448038 DOI: 10.1074/jbc.M110.104224] [Cited by in Crossref: 12] [Cited by in F6Publishing: 6] [Article Influence: 1.0] [Reference Citation Analysis]
78 Izumi KM, Cahir McFarland ED, Ting AT, Riley EA, Seed B, Kieff ED. The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation. Mol Cell Biol 1999;19:5759-67. [PMID: 10409763 DOI: 10.1128/MCB.19.8.5759] [Cited by in Crossref: 107] [Cited by in F6Publishing: 49] [Article Influence: 4.7] [Reference Citation Analysis]
79 Geetha T, Zheng C, McGregor WC, Douglas White B, Diaz-Meco MT, Moscat J, Babu JR. TRAF6 and p62 inhibit amyloid β-induced neuronal death through p75 neurotrophin receptor. Neurochem Int 2012;61:1289-93. [PMID: 23017601 DOI: 10.1016/j.neuint.2012.09.005] [Cited by in Crossref: 27] [Cited by in F6Publishing: 23] [Article Influence: 2.7] [Reference Citation Analysis]
80 Yada M, Hatakeyama S, Kamura T, Nishiyama M, Tsunematsu R, Imaki H, Ishida N, Okumura F, Nakayama K, Nakayama KI. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7. EMBO J. 2004;23:2116-2125. [PMID: 15103331 DOI: 10.1038/sj.emboj.7600217] [Cited by in Crossref: 502] [Cited by in F6Publishing: 493] [Article Influence: 27.9] [Reference Citation Analysis]
81 Neacsu P, Mazare A, Schmuki P, Cimpean A. Attenuation of the macrophage inflammatory activity by TiO₂ nanotubes via inhibition of MAPK and NF-κB pathways. Int J Nanomedicine 2015;10:6455-67. [PMID: 26491301 DOI: 10.2147/IJN.S92019] [Cited by in Crossref: 11] [Cited by in F6Publishing: 17] [Article Influence: 1.6] [Reference Citation Analysis]
82 Irelan JT, Murphy TJ, DeJesus PD, Teo H, Xu D, Gomez-Ferreria MA, Zhou Y, Miraglia LJ, Rines DR, Verma IM, Sharp DJ, Tergaonkar V, Chanda SK. A role for IkappaB kinase 2 in bipolar spindle assembly. Proc Natl Acad Sci U S A 2007;104:16940-5. [PMID: 17939994 DOI: 10.1073/pnas.0706493104] [Cited by in Crossref: 56] [Cited by in F6Publishing: 57] [Article Influence: 3.7] [Reference Citation Analysis]
83 Xu X, Woo CH, Steere RR, Lee BC, Huang Y, Wu J, Pang J, Lim JH, Xu H, Zhang W, Konduru AS, Yan C, Cheeseman MT, Brown SD, Li JD. EVI1 acts as an inducible negative-feedback regulator of NF-κB by inhibiting p65 acetylation. J Immunol 2012;188:6371-80. [PMID: 22581859 DOI: 10.4049/jimmunol.1103527] [Cited by in Crossref: 23] [Cited by in F6Publishing: 24] [Article Influence: 2.3] [Reference Citation Analysis]
84 Jiang Z, Mak TW, Sen G, Li X. Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta. Proc Natl Acad Sci USA. 2004;101:3533-3538. [PMID: 14982987 DOI: 10.1073/pnas.0308496101] [Cited by in Crossref: 257] [Cited by in F6Publishing: 263] [Article Influence: 14.3] [Reference Citation Analysis]
85 Heavey S, Godwin P, Baird AM, Barr MP, Umezawa K, Cuffe S, Finn SP, O'Byrne KJ, Gately K. Strategic targeting of the PI3K-NFκB axis in cisplatin-resistant NSCLC. Cancer Biol Ther 2014;15:1367-77. [PMID: 25025901 DOI: 10.4161/cbt.29841] [Cited by in Crossref: 16] [Cited by in F6Publishing: 16] [Article Influence: 2.0] [Reference Citation Analysis]
86 Jiang J, Zhang J, Wu C, Chen C, Bao G, Xu G, Xue P, Zhou Y, Sun Y, Cui Z. Knockdown of TRAF6 inhibits chondrocytes apoptosis and inflammation by suppressing the NF-κB pathway in lumbar facet joint osteoarthritis. Mol Cell Biochem 2021;476:1929-38. [PMID: 33502650 DOI: 10.1007/s11010-021-04048-x] [Reference Citation Analysis]
87 Leonardi M, Perna E, Tronnolone S, Colecchia D, Chiariello M. Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy. Autophagy. 2018;1-15. [PMID: 30289335 DOI: 10.1080/15548627.2018.1517855] [Cited by in Crossref: 14] [Cited by in F6Publishing: 17] [Article Influence: 3.5] [Reference Citation Analysis]
88 Darwech I, Otero JE, Alhawagri MA, Abu-Amer Y. Tyrosine phosphorylation is required for IkappaB kinase-beta (IKKbeta) activation and function in osteoclastogenesis. J Biol Chem 2010;285:25522-30. [PMID: 20534585 DOI: 10.1074/jbc.M110.121533] [Cited by in Crossref: 18] [Cited by in F6Publishing: 8] [Article Influence: 1.5] [Reference Citation Analysis]
89 Hayden MS, Ghosh S. NF-κB, the first quarter-century: remarkable progress and outstanding questions. Genes Dev. 2012;26:203-234. [PMID: 22302935 DOI: 10.1101/gad.183434.111] [Cited by in Crossref: 1034] [Cited by in F6Publishing: 1003] [Article Influence: 103.4] [Reference Citation Analysis]
90 Jamaluddin M, Casola A, Garofalo RP, Han Y, Elliott T, Ogra PL, Brasier AR. The major component of IkappaBalpha proteolysis occurs independently of the proteasome pathway in respiratory syncytial virus-infected pulmonary epithelial cells. J Virol 1998;72:4849-57. [PMID: 9573251 DOI: 10.1128/JVI.72.6.4849-4857.1998] [Cited by in Crossref: 66] [Cited by in F6Publishing: 32] [Article Influence: 2.8] [Reference Citation Analysis]
91 Lin KI, DiDonato JA, Hoffmann A, Hardwick JM, Ratan RR. Suppression of steady-state, but not stimulus-induced NF-kappaB activity inhibits alphavirus-induced apoptosis. J Cell Biol 1998;141:1479-87. [PMID: 9647642 DOI: 10.1083/jcb.141.7.1479] [Cited by in Crossref: 66] [Cited by in F6Publishing: 71] [Article Influence: 2.8] [Reference Citation Analysis]
92 Pan W, Zheng L, Gao J, Ye L, Chen Z, Liu S, Pan B, Fang J, Lai H, Zhang Y, Ni K, Lou C, He D. SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species. Biochem Pharmacol 2022;195:114846. [PMID: 34801525 DOI: 10.1016/j.bcp.2021.114846] [Reference Citation Analysis]
93 Li Q, Lu Q, Hwang JY, Büscher D, Lee KF, Izpisua-Belmonte JC, Verma IM. IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes Dev 1999;13:1322-8. [PMID: 10346820 DOI: 10.1101/gad.13.10.1322] [Cited by in Crossref: 381] [Cited by in F6Publishing: 368] [Article Influence: 16.6] [Reference Citation Analysis]
94 Li X, Commane M, Nie H, Hua X, Chatterjee-Kishore M, Wald D, Haag M, Stark GR. Act1, an NF-kappa B-activating protein. Proc Natl Acad Sci U S A 2000;97:10489-93. [PMID: 10962024 DOI: 10.1073/pnas.160265197] [Cited by in Crossref: 134] [Cited by in F6Publishing: 127] [Article Influence: 6.1] [Reference Citation Analysis]
95 Singh SS, Rai SN, Birla H, Zahra W, Rathore AS, Singh SP. NF-κB-Mediated Neuroinflammation in Parkinson's Disease and Potential Therapeutic Effect of Polyphenols. Neurotox Res 2020;37:491-507. [PMID: 31823227 DOI: 10.1007/s12640-019-00147-2] [Cited by in Crossref: 24] [Cited by in F6Publishing: 27] [Article Influence: 8.0] [Reference Citation Analysis]
96 Rahman I, MacNee W. Role of transcription factors in inflammatory lung diseases. Thorax 1998;53:601-12. [PMID: 9797762 DOI: 10.1136/thx.53.7.601] [Cited by in Crossref: 295] [Cited by in F6Publishing: 284] [Article Influence: 12.3] [Reference Citation Analysis]
97 Witherow DS, Garrison TR, Miller WE, Lefkowitz RJ. beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha. Proc Natl Acad Sci U S A. 2004;101:8603-8607. [PMID: 15173580 DOI: 10.1073/pnas.0402851101] [Cited by in Crossref: 181] [Cited by in F6Publishing: 177] [Article Influence: 10.1] [Reference Citation Analysis]
98 Majdalawieh A, Zhang L, Ro HS. Adipocyte enhancer-binding protein-1 promotes macrophage inflammatory responsiveness by up-regulating NF-kappaB via IkappaBalpha negative regulation. Mol Biol Cell 2007;18:930-42. [PMID: 17202411 DOI: 10.1091/mbc.e06-03-0217] [Cited by in Crossref: 36] [Cited by in F6Publishing: 26] [Article Influence: 2.4] [Reference Citation Analysis]
99 Gupta S, Purcell NH, Lin A, Sen S. Activation of nuclear factor-kappaB is necessary for myotrophin-induced cardiac hypertrophy. J Cell Biol 2002;159:1019-28. [PMID: 12486112 DOI: 10.1083/jcb.200207149] [Cited by in Crossref: 92] [Cited by in F6Publishing: 87] [Article Influence: 4.6] [Reference Citation Analysis]
100 Wallach D, Arumugam TU, Boldin MP, Cantarella G, Ganesh KA, Goltsev Y, Goncharov TM, Kovalenko AV, Rajput A, Varfolomeev EE, Zhang SQ. How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family. Arthritis Res 2002;4 Suppl 3:S189-96. [PMID: 12110139 DOI: 10.1186/ar585] [Cited by in Crossref: 25] [Cited by in F6Publishing: 26] [Article Influence: 1.3] [Reference Citation Analysis]
101 Hayashi T, Faustman D. NOD mice are defective in proteasome production and activation of NF-kappaB. Mol Cell Biol 1999;19:8646-59. [PMID: 10567588 DOI: 10.1128/MCB.19.12.8646] [Cited by in Crossref: 90] [Cited by in F6Publishing: 37] [Article Influence: 4.1] [Reference Citation Analysis]
102 Ueda Y, Richmond A. NF-kappaB activation in melanoma. Pigment Cell Res 2006;19:112-24. [PMID: 16524427 DOI: 10.1111/j.1600-0749.2006.00304.x] [Cited by in Crossref: 113] [Cited by in F6Publishing: 108] [Article Influence: 7.1] [Reference Citation Analysis]
103 Isakov N, Altman A. PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors. Front Immunol 2012;3:273. [PMID: 22936936 DOI: 10.3389/fimmu.2012.00273] [Cited by in Crossref: 53] [Cited by in F6Publishing: 55] [Article Influence: 5.3] [Reference Citation Analysis]
104 Xian-Xu Y, Pindolia KR, Janakiraman N, Chapman RA, Gautam SC. IL1α and TNFα Induction of Monocyte Chemoattractant Protein-1 (MCP-1/JE) in Bone Marrow Stromal Cells: The Role of Protein Kinase C (PKC) and Protein Tyrosine Kinase (PTK) Activity. Hematology 1998;3:235-50. [PMID: 27416533 DOI: 10.1080/10245332.1998.11746396] [Reference Citation Analysis]
105 Sanjuan MA, Rao N, Lai KT, Gu Y, Sun S, Fuchs A, Fung-Leung WP, Colonna M, Karlsson L. CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion. J Cell Biol 2006;172:1057-68. [PMID: 16567503 DOI: 10.1083/jcb.200508058] [Cited by in Crossref: 94] [Cited by in F6Publishing: 96] [Article Influence: 5.9] [Reference Citation Analysis]
106 Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Zhan F, Lenz G, Hanamura I, Wright G, Xiao W, Dave S, Hurt EM, Tan B, Zhao H, Stephens O, Santra M, Williams DR, Dang L, Barlogie B, Shaughnessy JD Jr, Kuehl WM, Staudt LM. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell. 2007;12:115-130. [PMID: 17692804 DOI: 10.1016/j.ccr.2007.07.004] [Cited by in Crossref: 701] [Cited by in F6Publishing: 659] [Article Influence: 46.7] [Reference Citation Analysis]
107 Bashyam MD, Bair R, Kim YH, Wang P, Hernandez-Boussard T, Karikari CA, Tibshirani R, Maitra A, Pollack JR. Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer. Neoplasia. 2005;7:556-562. [PMID: 16036106 DOI: 10.1593/neo.04586] [Cited by in Crossref: 137] [Cited by in F6Publishing: 132] [Article Influence: 8.1] [Reference Citation Analysis]
108 Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC. NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells. J Neurosci 2000;20:7556-63. [PMID: 11027214 [PMID: 11027214 DOI: 10.1523/jneurosci.20-20-07556.2000] [Cited by in Crossref: 102] [Article Influence: 4.9] [Reference Citation Analysis]
109 Gupta SC, Sundaram C, Reuter S, Aggarwal BB. Inhibiting NF-κB activation by small molecules as a therapeutic strategy. Biochim Biophys Acta. 2010;1799:775-787. [PMID: 20493977 DOI: 10.1016/j.bbagrm.2010.05.004] [Cited by in Crossref: 489] [Cited by in F6Publishing: 470] [Article Influence: 40.8] [Reference Citation Analysis]
110 Calzado MA, MacHo A, Lucena C, Muñoz E. Hydroxyurea inhibits the transactivation of the HIV-long-terminal repeat (LTR) promoter. Clin Exp Immunol 2000;120:317-23. [PMID: 10792382 DOI: 10.1046/j.1365-2249.2000.01203.x] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 0.5] [Reference Citation Analysis]
111 Smirnov AS, Budanov AV, Ruzov AS, Ivanov AV, Prokhorchuk AV, Gnuchev NV, Prokhorchuk EB. A high constitutive level of NF-κB is necessary for the viability of mouse adenocarcinoma cells: A possible role of p53. Mol Biol 2000;34:655-61. [DOI: 10.1007/bf02759603] [Reference Citation Analysis]
112 Karim ZA, Hensch NR, Qasim H, Alshbool FZ, Khasawneh FT. Role of IκB kinase β in regulating the remodeling of the CARMA1-Bcl10-MALT1 complex. Biochem Biophys Res Commun 2018;500:268-74. [PMID: 29649481 DOI: 10.1016/j.bbrc.2018.04.057] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
113 Lai W, Tian X, Xiang Q, Chu K, Wei Y, Deng J, Zhang S, Brown J, Hong G. 11β-HSD1 modulates LPS-induced innate immune responses in adipocytes by altering expression of PTEN. Mol Endocrinol 2015;29:558-70. [PMID: 25734515 DOI: 10.1210/me.2014-1287] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.6] [Reference Citation Analysis]
114 Moos PJ, Fitzpatrick FA. Taxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosis. Proc Natl Acad Sci U S A 1998;95:3896-901. [PMID: 9520464 DOI: 10.1073/pnas.95.7.3896] [Cited by in Crossref: 87] [Cited by in F6Publishing: 84] [Article Influence: 3.6] [Reference Citation Analysis]
115 Bonnard M, Mirtsos C, Suzuki S, Graham K, Huang J, Ng M, Itié A, Wakeham A, Shahinian A, Henzel WJ. Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription. EMBO J. 2000;19:4976-4985. [PMID: 10990461 DOI: 10.1093/emboj/19.18.4976] [Cited by in Crossref: 272] [Cited by in F6Publishing: 249] [Article Influence: 12.4] [Reference Citation Analysis]
116 Sachdev S, Hoffmann A, Hannink M. Nuclear localization of IkappaB alpha is mediated by the second ankyrin repeat: the IkappaB alpha ankyrin repeats define a novel class of cis-acting nuclear import sequences. Mol Cell Biol 1998;18:2524-34. [PMID: 9566872 DOI: 10.1128/MCB.18.5.2524] [Cited by in Crossref: 117] [Cited by in F6Publishing: 42] [Article Influence: 4.9] [Reference Citation Analysis]
117 Beinke S, Ley SC. Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology. Biochem J 2004;382:393-409. [PMID: 15214841 DOI: 10.1042/BJ20040544] [Cited by in Crossref: 421] [Cited by in F6Publishing: 180] [Article Influence: 24.8] [Reference Citation Analysis]
118 Finch A, Davis W, Carter WG, Saklatvala J. Analysis of mitogen-activated protein kinase pathways used by interleukin 1 in tissues in vivo: activation of hepatic c-Jun N-terminal kinases 1 and 2, and mitogen-activated protein kinase kinases 4 and 7. Biochem J 2001;353:275-81. [PMID: 11139391 DOI: 10.1042/0264-6021:3530275] [Cited by in Crossref: 7] [Cited by in F6Publishing: 10] [Article Influence: 0.3] [Reference Citation Analysis]
119 Sun W, Tan X, Shi Y, Xu G, Mao R, Gu X, Fan Y, Yu Y, Burlingame S, Zhang H. USP11 negatively regulates TNFalpha-induced NF-kappaB activation by targeting on IkappaBalpha. Cell Signal. 2010;22:386-394. [PMID: 19874889 DOI: 10.1016/j.cellsig.2009.10.008] [Cited by in Crossref: 73] [Cited by in F6Publishing: 65] [Article Influence: 6.1] [Reference Citation Analysis]
120 Abu-Amer Y. NF-κB signaling and bone resorption. Osteoporos Int 2013;24:2377-86. [PMID: 23468073 DOI: 10.1007/s00198-013-2313-x] [Cited by in Crossref: 155] [Cited by in F6Publishing: 149] [Article Influence: 17.2] [Reference Citation Analysis]
121 Rudolph D, Yeh W, Wakeham A, Rudolph B, Nallainathan D, Potter J, Elia AJ, Mak TW. Severe liver degeneration and lack of NFB activation in NEMO/IKKγ -deficient mice. Genes Dev 2000;14:854-62. [DOI: 10.1101/gad.14.7.854] [Cited by in Crossref: 89] [Cited by in F6Publishing: 7] [Article Influence: 4.0] [Reference Citation Analysis]
122 Kirschning CJ, Wesche H, Merrill Ayres T, Rothe M. Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J Exp Med 1998;188:2091-7. [PMID: 9841923 DOI: 10.1084/jem.188.11.2091] [Cited by in Crossref: 550] [Cited by in F6Publishing: 529] [Article Influence: 23.9] [Reference Citation Analysis]
123 Yang G, Xiao X, Rosen DG, Cheng X, Wu X, Chang B, Liu G, Xue F, Mercado-Uribe I, Chiao P, Du X, Liu J. The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer. Clin Cancer Res 2011;17:2181-94. [PMID: 21339307 DOI: 10.1158/1078-0432.CCR-10-3265] [Cited by in Crossref: 48] [Cited by in F6Publishing: 37] [Article Influence: 4.4] [Reference Citation Analysis]
124 Gomez AB, MacKenzie C, Paul A, Plevin R. Selective inhibition of inhibitory kappa B kinase-beta abrogates induction of nitric oxide synthase in lipopolysaccharide-stimulated rat aortic smooth muscle cells. Br J Pharmacol 2005;146:217-25. [PMID: 15997236 DOI: 10.1038/sj.bjp.0706308] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 0.6] [Reference Citation Analysis]
125 Ling L, Cao Z, Goeddel DV. NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176. Proc Natl Acad Sci U S A 1998;95:3792-7. [PMID: 9520446 DOI: 10.1073/pnas.95.7.3792] [Cited by in Crossref: 373] [Cited by in F6Publishing: 365] [Article Influence: 15.5] [Reference Citation Analysis]
126 Halsey TA, Yang L, Walker JR, Hogenesch JB, Thomas RS. A functional map of NFkappaB signaling identifies novel modulators and multiple system controls. Genome Biol 2007;8:R104. [PMID: 17553156 DOI: 10.1186/gb-2007-8-6-r104] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 1.1] [Reference Citation Analysis]
127 Seitz CS, Lin Q, Deng H, Khavari PA. Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB. Proc Natl Acad Sci U S A 1998;95:2307-12. [PMID: 9482881 DOI: 10.1073/pnas.95.5.2307] [Cited by in Crossref: 325] [Cited by in F6Publishing: 319] [Article Influence: 13.5] [Reference Citation Analysis]
128 Friedman JM, Horwitz MS. Inhibition of tumor necrosis factor alpha-induced NF-kappa B activation by the adenovirus E3-10.4/14.5K complex. J Virol 2002;76:5515-21. [PMID: 11991979 DOI: 10.1128/jvi.76.11.5515-5521.2002] [Cited by in Crossref: 44] [Cited by in F6Publishing: 23] [Article Influence: 2.2] [Reference Citation Analysis]
129 Shih RH, Wang CY, Yang CM. NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review. Front Mol Neurosci. 2015;8:77. [PMID: 26733801 DOI: 10.3389/fnmol.2015.00077] [Cited by in Crossref: 327] [Cited by in F6Publishing: 346] [Article Influence: 46.7] [Reference Citation Analysis]
130 Brown TT, Zelnik DL, Dobs AS. Fish oil supplementation in the treatment of cachexia in pancreatic cancer patients. Int J Gastrointest Cancer. 2003;34:143-150. [PMID: 15361649 DOI: 10.1385/ijgc:] [Cited by in F6Publishing: 4] [Reference Citation Analysis]
131 Kashyap T, Argueta C, Aboukameel A, Unger TJ, Klebanov B, Mohammad RM, Muqbil I, Azmi AS, Drolen C, Senapedis W, Lee M, Kauffman M, Shacham S, Landesman Y. Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death. Oncotarget 2016;7:78883-95. [PMID: 27713151 DOI: 10.18632/oncotarget.12428] [Cited by in Crossref: 50] [Cited by in F6Publishing: 47] [Article Influence: 12.5] [Reference Citation Analysis]
132 Pawson CT, Scott JD. Signal integration through blending, bolstering and bifurcating of intracellular information. Nat Struct Mol Biol 2010;17:653-8. [PMID: 20495562 DOI: 10.1038/nsmb.1843] [Cited by in Crossref: 47] [Cited by in F6Publishing: 44] [Article Influence: 3.9] [Reference Citation Analysis]
133 Kracklauer MP, Schmidt C. At the crossroads of SUMO and NF-kappaB. Mol Cancer 2003;2:39. [PMID: 14613580 DOI: 10.1186/1476-4598-2-39] [Cited by in Crossref: 15] [Cited by in F6Publishing: 15] [Article Influence: 0.8] [Reference Citation Analysis]
134 Chin AI, Shu J, Shan Shi C, Yao Z, Kehrl JH, Cheng G. TANK potentiates tumor necrosis factor receptor-associated factor-mediated c-Jun N-terminal kinase/stress-activated protein kinase activation through the germinal center kinase pathway. Mol Cell Biol 1999;19:6665-72. [PMID: 10490605 DOI: 10.1128/MCB.19.10.6665] [Cited by in Crossref: 35] [Cited by in F6Publishing: 12] [Article Influence: 1.6] [Reference Citation Analysis]
135 Rangaswami H, Bulbule A, Kundu GC. Nuclear factor inducing kinase: a key regulator in osteopontin- induced MAPK/IkappaB kinase dependent NF-kappaB-mediated promatrix metalloproteinase-9 activation. Glycoconj J 2006;23:221-32. [PMID: 16691505 DOI: 10.1007/s10719-006-7927-1] [Cited by in Crossref: 24] [Cited by in F6Publishing: 24] [Article Influence: 1.6] [Reference Citation Analysis]
136 Cerutti A, Schaffer A, Shah S, Zan H, Liou HC, Goodwin RG, Casali P. CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells. Immunity 1998;9:247-56. [PMID: 9729045 DOI: 10.1016/s1074-7613(00)80607-x] [Cited by in Crossref: 58] [Cited by in F6Publishing: 18] [Article Influence: 2.4] [Reference Citation Analysis]
137 Lin X, Mu Y, Cunningham ET Jr, Marcu KB, Geleziunas R, Greene WC. Molecular determinants of NF-kappaB-inducing kinase action. Mol Cell Biol 1998;18:5899-907. [PMID: 9742107 DOI: 10.1128/MCB.18.10.5899] [Cited by in Crossref: 107] [Cited by in F6Publishing: 40] [Article Influence: 4.5] [Reference Citation Analysis]
138 Chen WS, Chen CC, Chen LL, Lee CC, Huang TS. Secreted heat shock protein 90α (HSP90α) induces nuclear factor-κB-mediated TCF12 protein expression to down-regulate E-cadherin and to enhance colorectal cancer cell migration and invasion. J Biol Chem 2013;288:9001-10. [PMID: 23386606 DOI: 10.1074/jbc.M112.437897] [Cited by in Crossref: 53] [Cited by in F6Publishing: 35] [Article Influence: 5.9] [Reference Citation Analysis]
139 Schwenger P, Alpert D, Skolnik EY, Vilcek J. Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IkappaB alpha phosphorylation and degradation. Mol Cell Biol 1998;18:78-84. [PMID: 9418855 DOI: 10.1128/MCB.18.1.78] [Cited by in Crossref: 149] [Cited by in F6Publishing: 29] [Article Influence: 6.2] [Reference Citation Analysis]
140 Crépieux P, Kwon H, Leclerc N, Spencer W, Richard S, Lin R, Hiscott J. I kappaB alpha physically interacts with a cytoskeleton-associated protein through its signal response domain. Mol Cell Biol 1997;17:7375-85. [PMID: 9372968 DOI: 10.1128/MCB.17.12.7375] [Cited by in Crossref: 108] [Cited by in F6Publishing: 34] [Article Influence: 4.3] [Reference Citation Analysis]
141 Sathe SS, Sizemore N, Li X, Vithalani K, Commane M, Swiatkowski SM, Stark GR. Mutant human cells with constitutive activation of NF-kappaB. Proc Natl Acad Sci U S A 2004;101:192-7. [PMID: 14691254 DOI: 10.1073/pnas.0306812101] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 0.9] [Reference Citation Analysis]
142 Hezi-Yamit A, Wong PW, Bien-Ly N, Komuves LG, Prasad KS, Phillips DR, Sinha U. Synergistic induction of tissue factor by coagulation factor Xa and TNF: evidence for involvement of negative regulatory signaling cascades. Proc Natl Acad Sci USA. 2005;102:12077-12082. [PMID: 16105945 DOI: 10.1073/pnas.0504526102] [Cited by in Crossref: 44] [Cited by in F6Publishing: 41] [Article Influence: 2.6] [Reference Citation Analysis]
143 Guo SP, Wang WL, Zhai YQ, Zhao YL. Expression of nuclear factor-κB in hepatocellular carcinoma and its relation with the X protein of hepatitis B virus. World J Gastroenterol 2001; 7(3): 340-344 [PMID: 11819787 DOI: 10.3748/wjg.v7.i3.340] [Cited by in CrossRef: 28] [Cited by in F6Publishing: 32] [Article Influence: 1.3] [Reference Citation Analysis]
144 Hehner SP, Hofmann TG, Ushmorov A, Dienz O, Wing-Lan Leung I, Lassam N, Scheidereit C, Dröge W, Schmitz ML. Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex. Mol Cell Biol 2000;20:2556-68. [PMID: 10713178 DOI: 10.1128/MCB.20.7.2556-2568.2000] [Cited by in Crossref: 79] [Cited by in F6Publishing: 21] [Article Influence: 3.6] [Reference Citation Analysis]
145 Takaesu G, Ninomiya-Tsuji J, Kishida S, Li X, Stark GR, Matsumoto K. Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway. Mol Cell Biol 2001;21:2475-84. [PMID: 11259596 DOI: 10.1128/MCB.21.7.2475-2484.2001] [Cited by in Crossref: 147] [Cited by in F6Publishing: 59] [Article Influence: 7.0] [Reference Citation Analysis]
146 Aggarwal BB. Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB. Ann Rheum Dis 2000;59 Suppl 1:i6-16. [PMID: 11053079 DOI: 10.1136/ard.59.suppl_1.i6] [Cited by in Crossref: 149] [Cited by in F6Publishing: 145] [Article Influence: 6.8] [Reference Citation Analysis]
147 Drube S, Weber F, Göpfert C, Loschinski R, Rothe M, Boelke F, Diamanti MA, Löhn T, Ruth J, Schütz D, Häfner N, Greten FR, Stumm R, Hartmann K, Krämer OH, Dudeck A, Kamradt T. TAK1 and IKK2, novel mediators of SCF-induced signaling and potential targets for c-Kit-driven diseases. Oncotarget 2015;6:28833-50. [PMID: 26353931 DOI: 10.18632/oncotarget.5008] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 1.3] [Reference Citation Analysis]
148 Weil R, Sirma H, Giannini C, Kremsdorf D, Bessia C, Dargemont C, Brechot C, Israel A. Direct association and nuclear import of the hepatitis B virus X protein with the NF-kappaB inhibitor IkappaBalpha. Mol Cell Biol. 1999;19:6345-6354. [PMID: 10454581 DOI: 10.1128/mcb.19.9.6345] [Cited by in Crossref: 98] [Cited by in F6Publishing: 33] [Article Influence: 4.3] [Reference Citation Analysis]
149 Pontoriero M, Fiume G, Vecchio E, de Laurentiis A, Albano F, Iaccino E, Mimmi S, Pisano A, Agosti V, Giovannone E, Altobelli A, Caiazza C, Mallardo M, Scala G, Quinto I. Activation of NF-κB in B cell receptor signaling through Bruton's tyrosine kinase-dependent phosphorylation of IκB-α. J Mol Med (Berl) 2019;97:675-90. [PMID: 30887112 DOI: 10.1007/s00109-019-01777-x] [Cited by in Crossref: 20] [Cited by in F6Publishing: 21] [Article Influence: 6.7] [Reference Citation Analysis]
150 Holtmann H, Winzen R, Holland P, Eickemeier S, Hoffmann E, Wallach D, Malinin NL, Cooper JA, Resch K, Kracht M. Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways. Mol Cell Biol 1999;19:6742-53. [PMID: 10490613 DOI: 10.1128/MCB.19.10.6742] [Cited by in Crossref: 230] [Cited by in F6Publishing: 79] [Article Influence: 10.5] [Reference Citation Analysis]
151 Wang CN, Shiao YJ, Lin YL, Chen CF. Nepalolide A inhibits the expression of inducible nitric oxide synthase by modulating the degradation of IkappaB-alpha and IkappaB-beta in C6 glioma cells and rat primary astrocytes. Br J Pharmacol 1999;128:345-56. [PMID: 10510444 DOI: 10.1038/sj.bjp.0702785] [Cited by in Crossref: 9] [Cited by in F6Publishing: 7] [Article Influence: 0.4] [Reference Citation Analysis]
152 Huxford T, Ghosh G. A structural guide to proteins of the NF-kappaB signaling module. Cold Spring Harb Perspect Biol 2009;1:a000075. [PMID: 20066103 DOI: 10.1101/cshperspect.a000075] [Cited by in Crossref: 71] [Cited by in F6Publishing: 73] [Article Influence: 5.9] [Reference Citation Analysis]
153 Hinz M, Scheidereit C. The IκB kinase complex in NF-κB regulation and beyond. EMBO Rep 2014;15:46-61. [PMID: 24375677 DOI: 10.1002/embr.201337983] [Cited by in Crossref: 270] [Cited by in F6Publishing: 261] [Article Influence: 30.0] [Reference Citation Analysis]
154 Shinoura N, Yamamoto N, Yoshida Y, Fujita T, Saito N, Asai A, Kirino T, Hamada H. Adenovirus-mediated gene transduction of IkappaB or IkappaB plus Bax gene drastically enhances tumor necrosis factor (TNF)-induced apoptosis in human gliomas. Jpn J Cancer Res 2000;91:41-51. [PMID: 10744043 DOI: 10.1111/j.1349-7006.2000.tb00858.x] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 0.2] [Reference Citation Analysis]
155 Hatakeyama S, Kitagawa M, Nakayama K, Shirane M, Matsumoto M, Hattori K, Higashi H, Nakano H, Okumura K, Onoé K, Good RA, Nakayama K. Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1. Proc Natl Acad Sci U S A 1999;96:3859-63. [PMID: 10097128 DOI: 10.1073/pnas.96.7.3859] [Cited by in Crossref: 149] [Cited by in F6Publishing: 156] [Article Influence: 6.5] [Reference Citation Analysis]
156 Tacke F, Luedde T, Trautwein C. Inflammatory Pathways in Liver Homeostasis and Liver Injury. Clinic Rev Allerg Immunol 2009;36:4-12. [DOI: 10.1007/s12016-008-8091-0] [Cited by in Crossref: 254] [Cited by in F6Publishing: 248] [Article Influence: 18.1] [Reference Citation Analysis]
157 Cerutti A, Zan H, Kim EC, Shah S, Schattner EJ, Schaffer A, Casali P. Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells. J Immunol 2002;169:6594-603. [PMID: 12444172 DOI: 10.4049/jimmunol.169.11.6594] [Cited by in Crossref: 56] [Cited by in F6Publishing: 53] [Article Influence: 2.8] [Reference Citation Analysis]
158 Lin Y, Devin A, Cook A, Keane MM, Kelliher M, Lipkowitz S, Liu ZG. The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase. Mol Cell Biol 2000;20:6638-45. [PMID: 10958661 DOI: 10.1128/MCB.20.18.6638-6645.2000] [Cited by in Crossref: 167] [Cited by in F6Publishing: 67] [Article Influence: 7.6] [Reference Citation Analysis]
159 Lu Y, Wu LP, Anderson KV. The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase. Genes Dev 2001;15:104-10. [PMID: 11156609 DOI: 10.1101/gad.856901] [Cited by in Crossref: 138] [Cited by in F6Publishing: 131] [Article Influence: 6.6] [Reference Citation Analysis]
160 Xiao X, Yang G, Bai P, Gui S, Nyuyen TM, Mercado-Uribe I, Yang M, Zou J, Li Q, Xiao J, Chang B, Liu G, Wang H, Liu J. Inhibition of nuclear factor-kappa B enhances the tumor growth of ovarian cancer cell line derived from a low-grade papillary serous carcinoma in p53-independent pathway. BMC Cancer 2016;16:582. [PMID: 27484466 DOI: 10.1186/s12885-016-2617-2] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 2.5] [Reference Citation Analysis]
161 Tang F, Tang G, Xiang J, Dai Q, Rosner MR, Lin A. The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis. Mol Cell Biol 2002;22:8571-9. [PMID: 12446776 DOI: 10.1128/MCB.22.24.8571-8579.2002] [Cited by in Crossref: 103] [Cited by in F6Publishing: 54] [Article Influence: 5.4] [Reference Citation Analysis]
162 Xia Y, Chen S, Wang Y, Mackman N, Ku G, Lo D, Feng L. RelB modulation of IkappaBalpha stability as a mechanism of transcription suppression of interleukin-1alpha (IL-1alpha), IL-1beta, and tumor necrosis factor alpha in fibroblasts. Mol Cell Biol 1999;19:7688-96. [PMID: 10523657 DOI: 10.1128/MCB.19.11.7688] [Cited by in Crossref: 54] [Cited by in F6Publishing: 28] [Article Influence: 2.3] [Reference Citation Analysis]
163 Wang X, Li M, Zheng H, Muster T, Palese P, Beg AA, García-Sastre A. Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon. J Virol 2000;74:11566-73. [PMID: 11090154 DOI: 10.1128/jvi.74.24.11566-11573.2000] [Cited by in Crossref: 416] [Cited by in F6Publishing: 252] [Article Influence: 19.8] [Reference Citation Analysis]
164 Kadin ME. Regulation of CD30 antigen expression and its potential significance for human disease. Am J Pathol 2000;156:1479-84. [PMID: 10793058 DOI: 10.1016/S0002-9440(10)65018-3] [Cited by in Crossref: 35] [Cited by in F6Publishing: 13] [Article Influence: 1.6] [Reference Citation Analysis]
165 Bonizzi G, Piette J, Schoonbroodt S, Greimers R, Havard L, Merville MP, Bours V. Reactive oxygen intermediate-dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity. Mol Cell Biol 1999;19:1950-60. [PMID: 10022882 DOI: 10.1128/MCB.19.3.1950] [Cited by in Crossref: 169] [Cited by in F6Publishing: 60] [Article Influence: 7.3] [Reference Citation Analysis]
166 Qin H, Wilson CA, Lee SJ, Zhao X, Benveniste EN. LPS induces CD40 gene expression through the activation of NF-kappaB and STAT-1alpha in macrophages and microglia. Blood 2005;106:3114-22. [PMID: 16020513 DOI: 10.1182/blood-2005-02-0759] [Cited by in Crossref: 141] [Cited by in F6Publishing: 136] [Article Influence: 8.3] [Reference Citation Analysis]
167 Chandrakesan P, Jakkula LU, Ahmed I, Roy B, Anant S, Umar S. Differential effects of β-catenin and NF-κB interplay in the regulation of cell proliferation, inflammation and tumorigenesis in response to bacterial infection. PLoS One 2013;8:e79432. [PMID: 24278135 DOI: 10.1371/journal.pone.0079432] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 1.6] [Reference Citation Analysis]
168 Bauer S, Kirschning CJ, Häcker H, Redecke V, Hausmann S, Akira S, Wagner H, Lipford GB. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc Natl Acad Sci USA. 2001;98:9237-9242. [PMID: 11470918 DOI: 10.1073/pnas.161293498] [Cited by in Crossref: 1057] [Cited by in F6Publishing: 991] [Article Influence: 50.3] [Reference Citation Analysis]
169 Yamamoto Y, Yin MJ, Gaynor RB. IkappaB kinase alpha (IKKalpha) regulation of IKKbeta kinase activity. Mol Cell Biol 2000;20:3655-66. [PMID: 10779355 DOI: 10.1128/MCB.20.10.3655-3666.2000] [Cited by in Crossref: 44] [Cited by in F6Publishing: 15] [Article Influence: 2.0] [Reference Citation Analysis]
170 Park HH, Lo YC, Lin SC, Wang L, Yang JK, Wu H. The death domain superfamily in intracellular signaling of apoptosis and inflammation. Annu Rev Immunol 2007;25:561-86. [PMID: 17201679 DOI: 10.1146/annurev.immunol.25.022106.141656] [Cited by in Crossref: 353] [Cited by in F6Publishing: 324] [Article Influence: 23.5] [Reference Citation Analysis]
171 Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET Jr, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC. Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases. Mol Cell Biol 1998;18:5157-65. [PMID: 9710600 DOI: 10.1128/MCB.18.9.5157] [Cited by in Crossref: 163] [Cited by in F6Publishing: 66] [Article Influence: 6.8] [Reference Citation Analysis]
172 Bender K, Göttlicher M, Whiteside S, Rahmsdorf HJ, Herrlich P. Sequential DNA damage-independent and -dependent activation of NF-kappaB by UV. EMBO J 1998;17:5170-81. [PMID: 9724653 DOI: 10.1093/emboj/17.17.5170] [Cited by in Crossref: 181] [Cited by in F6Publishing: 170] [Article Influence: 7.5] [Reference Citation Analysis]
173 Squarize CH, Castilho RM, Sriuranpong V, Pinto DS, Gutkind JS. Molecular cross-talk between the NFkappaB and STAT3 signaling pathways in head and neck squamous cell carcinoma. Neoplasia. 2006;8:733-746. [PMID: 16984731 DOI: 10.1593/neo.06274] [Cited by in Crossref: 123] [Cited by in F6Publishing: 116] [Article Influence: 7.7] [Reference Citation Analysis]
174 Mercurio F, Murray BW, Shevchenko A, Bennett BL, Young DB, Li JW, Pascual G, Motiwala A, Zhu H, Mann M, Manning AM. IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex. Mol Cell Biol 1999;19:1526-38. [PMID: 9891086 DOI: 10.1128/MCB.19.2.1526] [Cited by in Crossref: 251] [Cited by in F6Publishing: 81] [Article Influence: 10.9] [Reference Citation Analysis]
175 Hay RT, Vuillard L, Desterro JM, Rodriguez MS. Control of NF-kappa B transcriptional activation by signal induced proteolysis of I kappa B alpha. Philos Trans R Soc Lond B Biol Sci 1999;354:1601-9. [PMID: 10582246 DOI: 10.1098/rstb.1999.0504] [Cited by in Crossref: 62] [Cited by in F6Publishing: 63] [Article Influence: 2.8] [Reference Citation Analysis]
176 Nakano H, Shindo M, Sakon S, Nishinaka S, Mihara M, Yagita H, Okumura K. Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1. Proc Natl Acad Sci USA. 1998;95:3537-3542. [PMID: 9520401 DOI: 10.1073/pnas.95.7.3537] [Cited by in Crossref: 414] [Cited by in F6Publishing: 402] [Article Influence: 17.3] [Reference Citation Analysis]
177 Jiang Z, Ninomiya-Tsuji J, Qian Y, Matsumoto K, Li X. Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol. Mol Cell Biol. 2002;22:7158-7167. [PMID: 12242293 DOI: 10.1128/MCB.22.20.7158-7167.2002] [Cited by in Crossref: 213] [Cited by in F6Publishing: 99] [Article Influence: 10.7] [Reference Citation Analysis]
178 Algarté M, Kwon H, Génin P, Hiscott J. Identification by in vivo genomic footprinting of a transcriptional switch containing NF-kappaB and Sp1 that regulates the IkappaBalpha promoter. Mol Cell Biol 1999;19:6140-53. [PMID: 10454561 DOI: 10.1128/MCB.19.9.6140] [Cited by in Crossref: 40] [Cited by in F6Publishing: 14] [Article Influence: 1.7] [Reference Citation Analysis]
179 Marie I. Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. The EMBO Journal;17:6660-9. [DOI: 10.1093/emboj/17.22.6660] [Cited by in Crossref: 779] [Cited by in F6Publishing: 759] [Article Influence: 32.5] [Reference Citation Analysis]
180 Kaisho T, Takeda K, Tsujimura T, Kawai T, Nomura F, Terada N, Akira S. IkappaB kinase alpha is essential for mature B cell development and function. J Exp Med 2001;193:417-26. [PMID: 11181694 DOI: 10.1084/jem.193.4.417] [Cited by in Crossref: 149] [Cited by in F6Publishing: 140] [Article Influence: 7.1] [Reference Citation Analysis]
181 Phromnoi K, Reuter S, Sung B, Prasad S, Kannappan R, Yadav VR, Chanmahasathien W, Limtrakul P, Aggarwal BB. A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents. Mol Pharmacol 2011;79:279-89. [PMID: 20930110 DOI: 10.1124/mol.110.067512] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.4] [Reference Citation Analysis]
182 Yao R, Wang Y, Lubet RA, You M. Differential gene expression in chemically induced mouse lung adenomas. Neoplasia 2003;5:41-52. [PMID: 12659669 DOI: 10.1016/s1476-5586(03)80016-7] [Cited by in Crossref: 15] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
183 Yang Z, Song L, Huang C. Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascades. Curr Cancer Drug Targets. 2009;9:915-930. [PMID: 20025601 DOI: 10.2174/156800909790192383] [Cited by in Crossref: 46] [Cited by in F6Publishing: 42] [Article Influence: 3.8] [Reference Citation Analysis]
184 Bonnet MC, Weil R, Dam E, Hovanessian AG, Meurs EF. PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex. Mol Cell Biol. 2000;20:4532-4542. [PMID: 10848580 DOI: 10.1128/MCB.20.13.4532-4542.2000] [Cited by in Crossref: 145] [Cited by in F6Publishing: 72] [Article Influence: 6.6] [Reference Citation Analysis]
185 Srinivasan D, Yen JH, Joseph DJ, Friedman W. Cell type-specific interleukin-1beta signaling in the CNS. J Neurosci 2004;24:6482-8. [PMID: 15269258 DOI: 10.1523/JNEUROSCI.5712-03.2004] [Cited by in Crossref: 132] [Cited by in F6Publishing: 71] [Article Influence: 7.8] [Reference Citation Analysis]
186 Qin T, Jia Y, Liu Y, Dai R, Zhou L, Okada S, Tsumura M, Ohnishi H, Kato Z, Kanegane H, Sun X, Zhao X. A Novel Homozygous Mutation Destabilizes IKKβ and Leads to Human Combined Immunodeficiency. Front Immunol 2020;11:517544. [PMID: 33658989 DOI: 10.3389/fimmu.2020.517544] [Reference Citation Analysis]
187 Wang HC, Hsu SP, Lee WS. Extra-Nuclear Signaling Pathway Involved in Progesterone-Induced Up-Regulations of p21cip1 and p27kip1 in Male Rat Aortic Smooth Muscle Cells. PLoS One 2015;10:e0125903. [PMID: 25932965 DOI: 10.1371/journal.pone.0125903] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 0.9] [Reference Citation Analysis]
188 Wang Q, Dziarski R, Kirschning CJ, Muzio M, Gupta D. Micrococci and peptidoglycan activate TLR2-->MyD88-->IRAK-->TRAF-->NIK-->IKK-->NF-kappaB signal transduction pathway that induces transcription of interleukin-8. Infect Immun. 2001;69:2270-2276. [PMID: 11254583 DOI: 10.1128/iai.69.4.2270-2276.2001] [Cited by in Crossref: 138] [Cited by in F6Publishing: 51] [Article Influence: 6.6] [Reference Citation Analysis]
189 Mori N, Ueda A, Geleziunas R, Wada A, Hirayama T, Yoshimura T, Yamamoto N. Induction of monocyte chemoattractant protein 1 by Helicobacter pylori involves NF-kappaB. Infect Immun. 2001;69:1280-1286. [PMID: 11179289 DOI: 10.1128/iai.69.3.1280-1286.2001] [Cited by in Crossref: 23] [Cited by in F6Publishing: 12] [Article Influence: 1.1] [Reference Citation Analysis]
190 Descargues P, Sil AK, Sano Y, Korchynskyi O, Han G, Owens P, Wang XJ, Karin M. IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation. Proc Natl Acad Sci U S A 2008;105:2487-92. [PMID: 18268325 DOI: 10.1073/pnas.0712044105] [Cited by in Crossref: 110] [Cited by in F6Publishing: 108] [Article Influence: 7.9] [Reference Citation Analysis]
191 Hansberger MW, Campbell JA, Danthi P, Arrate P, Pennington KN, Marcu KB, Ballard DW, Dermody TS. IkappaB kinase subunits alpha and gamma are required for activation of NF-kappaB and induction of apoptosis by mammalian reovirus. J Virol 2007;81:1360-71. [PMID: 17121808 DOI: 10.1128/JVI.01860-06] [Cited by in Crossref: 45] [Cited by in F6Publishing: 29] [Article Influence: 2.8] [Reference Citation Analysis]
192 Li X, Commane M, Burns C, Vithalani K, Cao Z, Stark GR. Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase. Mol Cell Biol 1999;19:4643-52. [PMID: 10373513 DOI: 10.1128/MCB.19.7.4643] [Cited by in Crossref: 173] [Cited by in F6Publishing: 73] [Article Influence: 7.5] [Reference Citation Analysis]
193 He KL, Ting AT. A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. Mol Cell Biol. 2002;22:6034-6045. [PMID: 12167698 DOI: 10.1128/mcb.22.17.6034-6045.2002] [Cited by in Crossref: 144] [Cited by in F6Publishing: 69] [Article Influence: 7.2] [Reference Citation Analysis]
194 Hay DC, Kemp GD, Dargemont C, Hay RT. Interaction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent transcription. Mol Cell Biol 2001;21:3482-90. [PMID: 11313474 DOI: 10.1128/MCB.21.10.3482-3490.2001] [Cited by in Crossref: 39] [Cited by in F6Publishing: 21] [Article Influence: 1.9] [Reference Citation Analysis]
195 Kitaura J, Asai K, Maeda-Yamamoto M, Kawakami Y, Kikkawa U, Kawakami T. Akt-dependent cytokine production in mast cells. J Exp Med 2000;192:729-40. [PMID: 10974038 DOI: 10.1084/jem.192.5.729] [Cited by in Crossref: 134] [Cited by in F6Publishing: 133] [Article Influence: 6.1] [Reference Citation Analysis]
196 Jin Y, Chai LJ, Hong J. Early expression of tumor necrosis factor α and nuclear factor kappa B after Descemet stripping endothelial keratoplasty in rabbits. Cornea 2012;31:913-9. [PMID: 22357389 DOI: 10.1097/ICO.0b013e31823f8be0] [Cited by in Crossref: 1] [Article Influence: 0.1] [Reference Citation Analysis]
197 Israël A. The IKK complex, a central regulator of NF-kappaB activation. Cold Spring Harb Perspect Biol 2010;2:a000158. [PMID: 20300203 DOI: 10.1101/cshperspect.a000158] [Cited by in Crossref: 428] [Cited by in F6Publishing: 430] [Article Influence: 35.7] [Reference Citation Analysis]
198 Majdalawieh A, Ro HS. Regulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophages. Mediators Inflamm 2010;2010:823821. [PMID: 20396415 DOI: 10.1155/2010/823821] [Cited by in Crossref: 51] [Cited by in F6Publishing: 48] [Article Influence: 4.3] [Reference Citation Analysis]
199 Hirano F, Chung M, Tanaka H, Maruyama N, Makino I, Moore DD, Scheidereit C. Alternative splicing variants of IkappaB beta establish differential NF-kappaB signal responsiveness in human cells. Mol Cell Biol 1998;18:2596-607. [PMID: 9566879 DOI: 10.1128/MCB.18.5.2596] [Cited by in Crossref: 37] [Cited by in F6Publishing: 9] [Article Influence: 1.5] [Reference Citation Analysis]
200 Torrie LJ, MacKenzie CJ, Paul A, Plevin R. Hydrogen peroxide-mediated inhibition of lipopolysaccharide-stimulated inhibitory kappa B kinase activity in rat aortic smooth muscle cells. Br J Pharmacol. 2001;134:393-401. [PMID: 11564658 DOI: 10.1038/sj.bjp.0704259] [Cited by in Crossref: 15] [Cited by in F6Publishing: 16] [Article Influence: 0.7] [Reference Citation Analysis]
201 Sylla BS, Hung SC, Davidson DM, Hatzivassiliou E, Malinin NL, Wallach D, Gilmore TD, Kieff E, Mosialos G. Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-kappaB through a pathway that includes the NF-kappaB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta. Proc Natl Acad Sci U S A 1998;95:10106-11. [PMID: 9707608 DOI: 10.1073/pnas.95.17.10106] [Cited by in Crossref: 118] [Cited by in F6Publishing: 120] [Article Influence: 4.9] [Reference Citation Analysis]
202 Sachdev S, Hannink M. Loss of IkappaB alpha-mediated control over nuclear import and DNA binding enables oncogenic activation of c-Rel. Mol Cell Biol. 1998;18:5445-5456. [PMID: 9710628 DOI: 10.1128/mcb.18.9.5445] [Cited by in Crossref: 36] [Cited by in F6Publishing: 16] [Article Influence: 1.5] [Reference Citation Analysis]
203 Miskin JE, Abrams CC, Dixon LK. African swine fever virus protein A238L interacts with the cellular phosphatase calcineurin via a binding domain similar to that of NFAT. J Virol 2000;74:9412-20. [PMID: 11000210 DOI: 10.1128/jvi.74.20.9412-9420.2000] [Cited by in Crossref: 49] [Cited by in F6Publishing: 16] [Article Influence: 2.2] [Reference Citation Analysis]
204 Orliaguet L, Ejlalmanesh T, Alzaid F. Metabolic and Molecular Mechanisms of Macrophage Polarisation and Adipose Tissue Insulin Resistance. Int J Mol Sci 2020;21:E5731. [PMID: 32785109 DOI: 10.3390/ijms21165731] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
205 García-García VA, Alameda JP, Page A, Casanova ML. Role of NF-κB in Ageing and Age-Related Diseases: Lessons from Genetically Modified Mouse Models. Cells 2021;10:1906. [PMID: 34440675 DOI: 10.3390/cells10081906] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
206 Fischer KC, Daunt CP, Tremblay CS, Dias S, Vince JE, Jabbour AM. Deletion of IKK2 in haematopoietic cells of adult mice leads to elevated interleukin-6, neutrophilia and fatal gastrointestinal inflammation. Cell Death Dis 2021;12:28. [PMID: 33414459 DOI: 10.1038/s41419-020-03298-9] [Reference Citation Analysis]
207 Anderson D, Macnee W. Targeted treatment in COPD: a multi-system approach for a multi-system disease. Int J Chron Obstruct Pulmon Dis 2009;4:321-35. [PMID: 19750192 DOI: 10.2147/copd.s2999] [Cited by in Crossref: 39] [Cited by in F6Publishing: 21] [Article Influence: 3.0] [Reference Citation Analysis]
208 Zhou L, Song F, Liu Q, Yang M, Zhao J, Tan R, Xu J, Zhang G, Quinn JM, Tickner J, Xu J. Berberine Sulfate Attenuates Osteoclast Differentiation through RANKL Induced NF-κB and NFAT Pathways. Int J Mol Sci 2015;16:27087-96. [PMID: 26580592 DOI: 10.3390/ijms161125998] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 2.6] [Reference Citation Analysis]
209 Sun W, Ge N, Yu Y, Burlingame S, Li X, Zhang M, Ye S, Fu S, Yang J. Phosphorylation of Thr-516 and Ser-520 in the kinase activation loop of MEKK3 is required for lysophosphatidic acid-mediated optimal IkappaB kinase beta (IKKbeta)/nuclear factor-kappaB (NF-kappaB) activation. J Biol Chem 2010;285:7911-8. [PMID: 20068038 DOI: 10.1074/jbc.M109.051219] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 0.7] [Reference Citation Analysis]
210 Sanz L, Sanchez P, Lallena MJ, Diaz-Meco MT, Moscat J. The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation. EMBO J 1999;18:3044-53. [PMID: 10356400 DOI: 10.1093/emboj/18.11.3044] [Cited by in Crossref: 277] [Cited by in F6Publishing: 279] [Article Influence: 12.0] [Reference Citation Analysis]
211 Li X, Commane M, Jiang Z, Stark GR. IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK). Proc Natl Acad Sci U S A 2001;98:4461-5. [PMID: 11287640 DOI: 10.1073/pnas.071054198] [Cited by in Crossref: 131] [Cited by in F6Publishing: 124] [Article Influence: 6.2] [Reference Citation Analysis]
212 Saccani S, Pantano S, Natoli G. Two waves of nuclear factor kappaB recruitment to target promoters. J Exp Med 2001;193:1351-9. [PMID: 11413190 DOI: 10.1084/jem.193.12.1351] [Cited by in Crossref: 292] [Cited by in F6Publishing: 294] [Article Influence: 13.9] [Reference Citation Analysis]
213 Li R, Yang L, Lindholm K, Konishi Y, Yue X, Hampel H, Zhang D, Shen Y. Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death. J Neurosci 2004;24:1760-71. [PMID: 14973251 DOI: 10.1523/JNEUROSCI.4580-03.2004] [Cited by in Crossref: 114] [Cited by in F6Publishing: 53] [Article Influence: 6.3] [Reference Citation Analysis]
214 Willmann KL, Sacco R, Martins R, Garncarz W, Krolo A, Knapp S, Bennett KL, Boztug K. Expanding the Interactome of the Noncanonical NF-κB Signaling Pathway. J Proteome Res 2016;15:2900-9. [PMID: 27416764 DOI: 10.1021/acs.jproteome.5b01004] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 1.0] [Reference Citation Analysis]
215 Lin X, O'Mahony A, Mu Y, Geleziunas R, Greene WC. Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta. Mol Cell Biol 2000;20:2933-40. [PMID: 10733597 DOI: 10.1128/MCB.20.8.2933-2940.2000] [Cited by in Crossref: 202] [Cited by in F6Publishing: 72] [Article Influence: 9.2] [Reference Citation Analysis]
216 Zandi E, Karin M. Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex. Mol Cell Biol. 1999;19:4547-4551. [PMID: 10373503 DOI: 10.1128/mcb.19.7.4547] [Cited by in Crossref: 254] [Cited by in F6Publishing: 74] [Article Influence: 11.0] [Reference Citation Analysis]
217 Abu-Amer Y. IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-kappaB. J Clin Invest 2001;107:1375-85. [PMID: 11390419 DOI: 10.1172/JCI10530] [Cited by in Crossref: 130] [Cited by in F6Publishing: 47] [Article Influence: 6.2] [Reference Citation Analysis]
218 Shifera AS. The zinc finger domain of IKKγ (NEMO) protein in health and disease. J Cell Mol Med 2010;14:2404-14. [PMID: 20345847 DOI: 10.1111/j.1582-4934.2010.01054.x] [Cited by in Crossref: 20] [Cited by in F6Publishing: 18] [Article Influence: 1.8] [Reference Citation Analysis]
219 Cerutti A, Schaffer A, Goodwin RG, Shah S, Zan H, Ely S, Casali P. Engagement of CD153 (CD30 ligand) by CD30+ T cells inhibits class switch DNA recombination and antibody production in human IgD+ IgM+ B cells. J Immunol 2000;165:786-94. [PMID: 10878352 DOI: 10.4049/jimmunol.165.2.786] [Cited by in Crossref: 72] [Cited by in F6Publishing: 70] [Article Influence: 3.3] [Reference Citation Analysis]
220 Joneson T, Bar-Sagi D. Suppression of Ras-induced apoptosis by the Rac GTPase. Mol Cell Biol 1999;19:5892-901. [PMID: 10454536 DOI: 10.1128/MCB.19.9.5892] [Cited by in Crossref: 135] [Cited by in F6Publishing: 45] [Article Influence: 5.9] [Reference Citation Analysis]
221 Li Y, Kang J, Friedman J, Tarassishin L, Ye J, Kovalenko A, Wallach D, Horwitz MS. Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis. Proc Natl Acad Sci U S A 1999;96:1042-7. [PMID: 9927690 DOI: 10.1073/pnas.96.3.1042] [Cited by in Crossref: 130] [Cited by in F6Publishing: 132] [Article Influence: 5.7] [Reference Citation Analysis]
222 Liu L, Kwak YT, Bex F, García-Martínez LF, Li XH, Meek K, Lane WS, Gaynor RB. DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties. Mol Cell Biol 1998;18:4221-34. [PMID: 9632806 DOI: 10.1128/MCB.18.7.4221] [Cited by in Crossref: 60] [Cited by in F6Publishing: 18] [Article Influence: 2.5] [Reference Citation Analysis]
223 Lallena MJ, Diaz-Meco MT, Bren G, Payá CV, Moscat J. Activation of IkappaB kinase beta by protein kinase C isoforms. Mol Cell Biol 1999;19:2180-8. [PMID: 10022904 DOI: 10.1128/MCB.19.3.2180] [Cited by in Crossref: 285] [Cited by in F6Publishing: 79] [Article Influence: 12.4] [Reference Citation Analysis]
224 Ahmad A, Crupi R, Campolo M, Genovese T, Esposito E, Cuzzocrea S. Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice. PLoS One 2013;8:e57208. [PMID: 23555560 DOI: 10.1371/journal.pone.0057208] [Cited by in Crossref: 76] [Cited by in F6Publishing: 75] [Article Influence: 8.4] [Reference Citation Analysis]
225 Kwon HJ, Breese EH, Vig-Varga E, Luo Y, Lee Y, Goebl MG, Harrington MA. Tumor necrosis factor alpha induction of NF-kappaB requires the novel coactivator SIMPL. Mol Cell Biol 2004;24:9317-26. [PMID: 15485901 DOI: 10.1128/MCB.24.21.9317-9326.2004] [Cited by in Crossref: 20] [Cited by in F6Publishing: 9] [Article Influence: 1.1] [Reference Citation Analysis]
226 Schuster M, Annemann M, Plaza-Sirvent C, Schmitz I. Atypical IκB proteins - nuclear modulators of NF-κB signaling. Cell Commun Signal 2013;11:23. [PMID: 23578005 DOI: 10.1186/1478-811X-11-23] [Cited by in Crossref: 54] [Cited by in F6Publishing: 30] [Article Influence: 6.0] [Reference Citation Analysis]
227 Foxwell B, Browne K, Bondeson J, Clarke C, de Martin R, Brennan F, Feldmann M. Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent. Proc Natl Acad Sci U S A 1998;95:8211-5. [PMID: 9653166 DOI: 10.1073/pnas.95.14.8211] [Cited by in Crossref: 193] [Cited by in F6Publishing: 199] [Article Influence: 8.0] [Reference Citation Analysis]
228 McKenzie FR, Connelly MA, Balzarano D, Müller JR, Geleziunas R, Marcu KB. Functional isoforms of IkappaB kinase alpha (IKKalpha) lacking leucine zipper and helix-loop-helix domains reveal that IKKalpha and IKKbeta have different activation requirements. Mol Cell Biol 2000;20:2635-49. [PMID: 10733566 DOI: 10.1128/MCB.20.8.2635-2649.2000] [Cited by in Crossref: 15] [Cited by in F6Publishing: 5] [Article Influence: 0.7] [Reference Citation Analysis]
229 Béraud C, Henzel WJ, Baeuerle PA. Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation. Proc Natl Acad Sci USA. 1999;96:429-434. [PMID: 9892650 DOI: 10.1073/pnas.96.2.429] [Cited by in Crossref: 228] [Cited by in F6Publishing: 227] [Article Influence: 9.9] [Reference Citation Analysis]
230 Lee FS, Peters RT, Dang LC, Maniatis T. MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta. Proc Natl Acad Sci U S A 1998;95:9319-24. [PMID: 9689078 DOI: 10.1073/pnas.95.16.9319] [Cited by in Crossref: 299] [Cited by in F6Publishing: 297] [Article Influence: 12.5] [Reference Citation Analysis]
231 Mughal MJ, Xi P, Yi Z, Jing F. Aflatoxin B1 invokes apoptosis via death receptor pathway in hepatocytes. Oncotarget 2017;8:8239-49. [PMID: 28030812 DOI: 10.18632/oncotarget.14158] [Cited by in Crossref: 40] [Cited by in F6Publishing: 37] [Article Influence: 10.0] [Reference Citation Analysis]
232 Miraghazadeh B, Cook MC. Nuclear Factor-kappaB in Autoimmunity: Man and Mouse. Front Immunol 2018;9:613. [PMID: 29686669 DOI: 10.3389/fimmu.2018.00613] [Cited by in Crossref: 44] [Cited by in F6Publishing: 46] [Article Influence: 11.0] [Reference Citation Analysis]
233 Baeza-Raja B, Muñoz-Cánoves P. p38 MAPK-induced nuclear factor-kappaB activity is required for skeletal muscle differentiation: role of interleukin-6. Mol Biol Cell 2004;15:2013-26. [PMID: 14767066 DOI: 10.1091/mbc.e03-08-0585] [Cited by in Crossref: 171] [Cited by in F6Publishing: 114] [Article Influence: 9.5] [Reference Citation Analysis]
234 Li N, Karin M. Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms. Proc Natl Acad Sci U S A 1998;95:13012-7. [PMID: 9789032 DOI: 10.1073/pnas.95.22.13012] [Cited by in Crossref: 318] [Cited by in F6Publishing: 305] [Article Influence: 13.3] [Reference Citation Analysis]
235 Sha WC. Regulation of immune responses by NF-kappa B/Rel transcription factor. J Exp Med. 1998;187:143-146. [PMID: 9432972 DOI: 10.1084/jem.187.2.143] [Cited by in Crossref: 160] [Cited by in F6Publishing: 151] [Article Influence: 6.7] [Reference Citation Analysis]
236 Choi SH, Park KJ, Ahn BY, Jung G, Lai MM, Hwang SB. Hepatitis C virus nonstructural 5B protein regulates tumor necrosis factor alpha signaling through effects on cellular IkappaB kinase. Mol Cell Biol. 2006;26:3048-3059. [PMID: 16581780 DOI: 10.1128/mcb.26.8.3048-3059.2006] [Cited by in Crossref: 32] [Cited by in F6Publishing: 19] [Article Influence: 2.0] [Reference Citation Analysis]
237 Cameron P, Bingham D, Paul A, Pavelka M, Cameron S, Rotondo D, Plevin R. Essential role for verotoxin in sustained stress-activated protein kinase and nuclear factor kappa B signaling, stimulated by Escherichia coli O157:H7 in Vero cells. Infect Immun 2002;70:5370-80. [PMID: 12228261 DOI: 10.1128/IAI.70.10.5370-5380.2002] [Cited by in Crossref: 12] [Cited by in F6Publishing: 7] [Article Influence: 0.6] [Reference Citation Analysis]
238 Lin Y, Devin A, Rodriguez Y, Liu ZG. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 1999;13:2514-26. [PMID: 10521396 DOI: 10.1101/gad.13.19.2514] [Cited by in Crossref: 579] [Cited by in F6Publishing: 571] [Article Influence: 25.2] [Reference Citation Analysis]
239 Yaron A, Gonen H, Alkalay I, Hatzubai A, Jung S, Beyth S, Mercurio F, Manning AM, Ciechanover A, Ben-Neriah Y. Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase. EMBO J 1997;16:6486-94. [PMID: 9351830 DOI: 10.1093/emboj/16.21.6486] [Cited by in Crossref: 178] [Cited by in F6Publishing: 170] [Article Influence: 7.4] [Reference Citation Analysis]
240 Arya R, Mallik M, Lakhotia SC. Heat shock genes - integrating cell survival and death. J Biosci. 2007;32:595-610. [PMID: 17536179 DOI: 10.1007/s12038-007-0059-3] [Cited by in Crossref: 328] [Cited by in F6Publishing: 302] [Article Influence: 21.9] [Reference Citation Analysis]
241 Cieniewicz B, Santana AL, Minkah N, Krug LT. Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host. Front Microbiol 2016;7:1202. [PMID: 27582728 DOI: 10.3389/fmicb.2016.01202] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 2.2] [Reference Citation Analysis]
242 Verma IM, Stevenson J. IkappaB kinase: beginning, not the end. Proc Natl Acad Sci U S A 1997;94:11758-60. [PMID: 9342307 DOI: 10.1073/pnas.94.22.11758] [Cited by in Crossref: 148] [Cited by in F6Publishing: 146] [Article Influence: 5.9] [Reference Citation Analysis]
243 Woo JT, Kato M, Takami M, Nagai K. Receptor activator of NF-kappaB ligand induces the fusion of mononuclear preosteoclasts into multinucleated osteoclasts. Cytotechnology 2000;33:203-11. [PMID: 19002827 DOI: 10.1023/A:1008198120670] [Cited by in Crossref: 2] [Article Influence: 0.1] [Reference Citation Analysis]
244 Harhaj EW, Sun SC. Regulation of RelA subcellular localization by a putative nuclear export signal and p50. Mol Cell Biol 1999;19:7088-95. [PMID: 10490645 DOI: 10.1128/MCB.19.10.7088] [Cited by in F6Publishing: 34] [Reference Citation Analysis]
245 Trushin SA, Pennington KN, Carmona EM, Asin S, Savoy DN, Billadeau DD, Paya CV. Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes. Mol Cell Biol. 2003;23:7068-7081. [PMID: 12972622 DOI: 10.1128/MCB.23.19.7068-7081.2003] [Cited by in Crossref: 94] [Cited by in F6Publishing: 44] [Article Influence: 4.9] [Reference Citation Analysis]
246 Achoui M, Appleton D, Abdulla MA, Awang K, Mohd MA, Mustafa MR. In vitro and in vivo anti-inflammatory activity of 17-O-acetylacuminolide through the inhibition of cytokines, NF-κB translocation and IKKβ activity. PLoS One 2010;5:e15105. [PMID: 21152019 DOI: 10.1371/journal.pone.0015105] [Cited by in Crossref: 18] [Cited by in F6Publishing: 20] [Article Influence: 1.5] [Reference Citation Analysis]
247 Descargues P, Sil AK, Karin M. IKKalpha, a critical regulator of epidermal differentiation and a suppressor of skin cancer. EMBO J 2008;27:2639-47. [PMID: 18818691 DOI: 10.1038/emboj.2008.196] [Cited by in Crossref: 65] [Cited by in F6Publishing: 60] [Article Influence: 4.6] [Reference Citation Analysis]
248 Huang H, Calderon TM, Berman JW, Braunstein VL, Weiss LM, Wittner M, Tanowitz HB. Infection of endothelial cells with Trypanosoma cruzi activates NF-kappaB and induces vascular adhesion molecule expression. Infect Immun 1999;67:5434-40. [PMID: 10496926 DOI: 10.1128/IAI.67.10.5434-5440.1999] [Cited by in Crossref: 60] [Cited by in F6Publishing: 36] [Article Influence: 2.6] [Reference Citation Analysis]
249 Li X, Qin J. Modulation of Toll-interleukin 1 receptor mediated signaling. J Mol Med. 2005;83:258-266. [PMID: 15662540 DOI: 10.1007/s00109-004-0622-4] [Cited by in Crossref: 110] [Cited by in F6Publishing: 103] [Article Influence: 6.5] [Reference Citation Analysis]
250 Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol 2002;22:3549-61. [PMID: 11971985 DOI: 10.1128/MCB.22.10.3549-3561.2002] [Cited by in Crossref: 209] [Cited by in F6Publishing: 104] [Article Influence: 10.5] [Reference Citation Analysis]
251 Zhao W, Breese E, Bowers A, Hoggatt J, Pelus LM, Broxmeyer HE, Goebl M, Harrington MA. SIMPL enhancement of tumor necrosis factor-α dependent p65-MED1 complex formation is required for mammalian hematopoietic stem and progenitor cell function. PLoS One 2013;8:e61123. [PMID: 23630580 DOI: 10.1371/journal.pone.0061123] [Cited by in Crossref: 2] [Cited by in F6Publishing: 4] [Article Influence: 0.2] [Reference Citation Analysis]
252 Wu K, Fuchs SY, Chen A, Tan P, Gomez C, Ronai Z, Pan ZQ. The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation. Mol Cell Biol 2000;20:1382-93. [PMID: 10648623 DOI: 10.1128/MCB.20.4.1382-1393.2000] [Cited by in Crossref: 79] [Cited by in F6Publishing: 47] [Article Influence: 3.6] [Reference Citation Analysis]