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For: Ferguson EC, Rathmell JC. New roles for pyruvate kinase M2: working out the Warburg effect. Trends Biochem Sci. 2008;33:359-362. [PMID: 18603432 DOI: 10.1016/j.tibs.2008.05.006] [Cited by in Crossref: 43] [Cited by in F6Publishing: 44] [Article Influence: 3.1] [Reference Citation Analysis]
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4 Xu Q, Liu L, Yin Y, He J, Li Q, Qian X, You Y, Lu Z, Peiper SC, Shu Y, Jiang B. Regulatory circuit of PKM2/NF-κB/miR-148a/152-modulated tumor angiogenesis and cancer progression. Oncogene 2015;34:5482-93. [DOI: 10.1038/onc.2015.6] [Cited by in Crossref: 48] [Cited by in F6Publishing: 52] [Article Influence: 6.9] [Reference Citation Analysis]
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6 Yuan Q, Yu H, Chen J, Song X, Sun L. Knockdown of pyruvate kinase type M2 suppresses tumor survival and invasion in osteosarcoma cells both in vitro and in vivo. Exp Cell Res 2018;362:209-16. [PMID: 29155364 DOI: 10.1016/j.yexcr.2017.11.020] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 1.6] [Reference Citation Analysis]
7 Daher M, Widom JR, Tay W, Walter NG. Soft Interactions with Model Crowders and Non-canonical Interactions with Cellular Proteins Stabilize RNA Folding. J Mol Biol 2018;430:509-23. [PMID: 29128594 DOI: 10.1016/j.jmb.2017.10.030] [Cited by in Crossref: 13] [Cited by in F6Publishing: 10] [Article Influence: 2.6] [Reference Citation Analysis]
8 Lee SY, Ju MK, Jeon HM, Lee YJ, Kim CH, Park HG, Han SI, Kang HS. Oncogenic Metabolism Acts as a Prerequisite Step for Induction of Cancer Metastasis and Cancer Stem Cell Phenotype. Oxid Med Cell Longev. 2018;2018:1027453. [PMID: 30671168 DOI: 10.1155/2018/1027453] [Cited by in Crossref: 28] [Cited by in F6Publishing: 30] [Article Influence: 7.0] [Reference Citation Analysis]
9 Bi YH, Han WQ, Li RF, Wang YJ, Du ZS, Wang XJ, Jiang Y. Signal transducer and activator of transcription 3 promotes the Warburg effect possibly by inducing pyruvate kinase M2 phosphorylation in liver precancerous lesions. World J Gastroenterol 2019; 25(16): 1936-1949 [PMID: 31086462 DOI: 10.3748/wjg.v25.i16.1936] [Cited by in CrossRef: 7] [Cited by in F6Publishing: 7] [Article Influence: 2.3] [Reference Citation Analysis]
10 Sun H, Zhu A, Zhang L, Zhang J, Zhong Z, Wang F. Knockdown of PKM2 Suppresses Tumor Growth and Invasion in Lung Adenocarcinoma. Int J Mol Sci 2015;16:24574-87. [PMID: 26501265 DOI: 10.3390/ijms161024574] [Cited by in Crossref: 35] [Cited by in F6Publishing: 37] [Article Influence: 5.0] [Reference Citation Analysis]
11 Voisin SN, Krakovska O, Matta A, DeSouza LV, Romaschin AD, Colgan TJ, Siu KW. Identification of novel molecular targets for endometrial cancer using a drill-down LC-MS/MS approach with iTRAQ. PLoS One 2011;6:e16352. [PMID: 21305022 DOI: 10.1371/journal.pone.0016352] [Cited by in Crossref: 34] [Cited by in F6Publishing: 33] [Article Influence: 3.1] [Reference Citation Analysis]
12 Altman BJ, Dang CV. Normal and cancer cell metabolism: lymphocytes and lymphoma. FEBS J. 2012;279:2598-2609. [PMID: 22672505 DOI: 10.1111/j.1742-4658.2012.08651.x] [Cited by in Crossref: 40] [Cited by in F6Publishing: 39] [Article Influence: 4.0] [Reference Citation Analysis]
13 Upadhyay M, Samal J, Kandpal M, Singh OV, Vivekanandan P. The Warburg effect: insights from the past decade. Pharmacol Ther 2013;137:318-30. [PMID: 23159371 DOI: 10.1016/j.pharmthera.2012.11.003] [Cited by in Crossref: 126] [Cited by in F6Publishing: 119] [Article Influence: 12.6] [Reference Citation Analysis]
14 Shin S, Kwon YJ, Ye DJ, Baek HS, Kwon TU, Kim D, Chun YJ. Human steroid sulfatase enhances aerobic glycolysis through induction of HIF1α and glycolytic enzymes. Biochim Biophys Acta Mol Basis Dis 2019;1865:2464-74. [PMID: 31195119 DOI: 10.1016/j.bbadis.2019.06.005] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
15 Li L, Peng G, Liu X, Zhang Y, Han H, Liu ZR. Pyruvate Kinase M2 Coordinates Metabolism Switch between Glycolysis and Glutaminolysis in Cancer Cells. iScience 2020;23:101684. [PMID: 33196019 DOI: 10.1016/j.isci.2020.101684] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
16 Yang L, Hou Y, Yuan J, Tang S, Zhang H, Zhu Q, Du YE, Zhou M, Wen S, Xu L, Tang X, Cui X, Liu M. Twist promotes reprogramming of glucose metabolism in breast cancer cells through PI3K/AKT and p53 signaling pathways. Oncotarget 2015;6:25755-69. [PMID: 26342198 DOI: 10.18632/oncotarget.4697] [Cited by in Crossref: 61] [Cited by in F6Publishing: 57] [Article Influence: 10.2] [Reference Citation Analysis]
17 Wittwer JA, Robbins D, Wang F, Codarin S, Shen X, Kevil CG, Huang TT, Van Remmen H, Richardson A, Zhao Y. Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells. Cancer Prev Res (Phila) 2011;4:1476-84. [PMID: 21673231 DOI: 10.1158/1940-6207.CAPR-11-0028] [Cited by in Crossref: 23] [Cited by in F6Publishing: 14] [Article Influence: 2.1] [Reference Citation Analysis]
18 Liu X, Wang X, Zhang J, Lam EK, Shin VY, Cheng AS, Yu J, Chan FK, Sung JJ, Jin HC. Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis. Oncogene. 2010;29:442-450. [PMID: 19881551 DOI: 10.1038/onc.2009.332] [Cited by in Crossref: 110] [Cited by in F6Publishing: 113] [Article Influence: 8.5] [Reference Citation Analysis]
19 Gupta V, Bamezai RN. Human pyruvate kinase M2: a multifunctional protein. Protein Sci. 2010;19:2031-2044. [PMID: 20857498 DOI: 10.1002/pro.505] [Cited by in Crossref: 152] [Cited by in F6Publishing: 139] [Article Influence: 13.8] [Reference Citation Analysis]
20 Gu Z, Xia J, Xu H, Frech I, Tricot G, Zhan F. NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase. J Hematol Oncol 2017;10:17. [PMID: 28086949 DOI: 10.1186/s13045-017-0392-4] [Cited by in Crossref: 45] [Cited by in F6Publishing: 49] [Article Influence: 9.0] [Reference Citation Analysis]
21 Nicholson J, Neelagandan K, Huart AS, Ball K, Molloy MP, Hupp T. An iTRAQ proteomics screen reveals the effects of the MDM2 binding ligand Nutlin-3 on cellular proteostasis. J Proteome Res 2012;11:5464-78. [PMID: 23039052 DOI: 10.1021/pr300698d] [Cited by in Crossref: 21] [Cited by in F6Publishing: 22] [Article Influence: 2.1] [Reference Citation Analysis]
22 Gupta V, Iqbal MA, Kumar B, Bamezai RNK. Pyruvate Kinase M2: A Metabolic Tuner. In: Mazurek S, Shoshan M, editors. Tumor Cell Metabolism. Vienna: Springer; 2015. pp. 123-42. [DOI: 10.1007/978-3-7091-1824-5_6] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.1] [Reference Citation Analysis]
23 Swerdlow RH. Bioenergetic medicine. Br J Pharmacol 2014;171:1854-69. [PMID: 24004341 DOI: 10.1111/bph.12394] [Cited by in Crossref: 30] [Cited by in F6Publishing: 28] [Article Influence: 3.8] [Reference Citation Analysis]
24 Fogal V, Richardson AD, Karmali PP, Scheffler IE, Smith JW, Ruoslahti E. Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation. Mol Cell Biol 2010;30:1303-18. [PMID: 20100866 DOI: 10.1128/MCB.01101-09] [Cited by in F6Publishing: 126] [Reference Citation Analysis]
25 Higareda-Almaraz JC, Valtierra-Gutiérrez IA, Hernandez-Ortiz M, Contreras S, Hernandez E, Encarnación-Guevara S. Analysis and prediction of pathways in HeLa cells by integrating biological levels of organization with systems-biology approaches. PLoS One 2013;8:e65433. [PMID: 23785426 DOI: 10.1371/journal.pone.0065433] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 0.9] [Reference Citation Analysis]
26 Chaman N, Iqbal MA, Siddiqui FA, Gopinath P, Bamezai RN. ERK2-Pyruvate Kinase Axis Permits Phorbol 12-Myristate 13-Acetate-induced Megakaryocyte Differentiation in K562 Cells. J Biol Chem 2015;290:23803-15. [PMID: 26269597 DOI: 10.1074/jbc.M115.657411] [Cited by in Crossref: 9] [Cited by in F6Publishing: 4] [Article Influence: 1.3] [Reference Citation Analysis]
27 Robert G, Jacquel A, Auberger P. Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies. Cells 2019;8:E1260. [PMID: 31623164 DOI: 10.3390/cells8101260] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 2.7] [Reference Citation Analysis]
28 Allali-hassani A, Wasney G, Chau I, Hong B, Senisterra G, Loppnau P, Shi Z, Moult J, Edwards A, Arrowsmith C, Park H, Schapira M, Vedadi M. A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity. Biochemical Journal 2009;424:15-26. [DOI: 10.1042/bj20090723] [Cited by in Crossref: 37] [Cited by in F6Publishing: 25] [Article Influence: 2.8] [Reference Citation Analysis]
29 Park SH, Ozden O, Liu G, Song HY, Zhu Y, Yan Y, Zou X, Kang HJ, Jiang H, Principe DR, Cha YI, Roh M, Vassilopoulos A, Gius D. SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth. Cancer Res 2016;76:3802-12. [PMID: 27197174 DOI: 10.1158/0008-5472.CAN-15-2498] [Cited by in Crossref: 55] [Cited by in F6Publishing: 36] [Article Influence: 9.2] [Reference Citation Analysis]
30 Yang X, Chen H, Zhu M, Zhu R, Qin B, Fang H, Dai M, Sang A, Liu X. Up-Regulation of PKM2 Relates to Retinal Ganglion Cell Apoptosis After Light-Induced Retinal Damage in Adult Rats. Cell Mol Neurobiol 2015;35:1175-86. [PMID: 25990228 DOI: 10.1007/s10571-015-0211-9] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 1.4] [Reference Citation Analysis]
31 Higareda-Almaraz JC, Enríquez-Gasca Mdel R, Hernández-Ortiz M, Resendis-Antonio O, Encarnación-Guevara S. Proteomic patterns of cervical cancer cell lines, a network perspective. BMC Syst Biol 2011;5:96. [PMID: 21696634 DOI: 10.1186/1752-0509-5-96] [Cited by in Crossref: 39] [Cited by in F6Publishing: 40] [Article Influence: 3.5] [Reference Citation Analysis]
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33 Liu S, Cheng C. Alternative RNA splicing and cancer. Wiley Interdiscip Rev RNA 2013;4:547-66. [PMID: 23765697 DOI: 10.1002/wrna.1178] [Cited by in Crossref: 55] [Cited by in F6Publishing: 60] [Article Influence: 6.1] [Reference Citation Analysis]
34 Li W, Wang J, Chen QD, Qian X, Li Q, Yin Y, Shi ZM, Wang L, Lin J, Liu LZ, Jiang BH. Insulin promotes glucose consumption via regulation of miR-99a/mTOR/PKM2 pathway. PLoS One 2013;8:e64924. [PMID: 23762265 DOI: 10.1371/journal.pone.0064924] [Cited by in Crossref: 24] [Cited by in F6Publishing: 27] [Article Influence: 2.7] [Reference Citation Analysis]
35 Librán-Pérez M, Costa MM, Figueras A, Novoa B. β-glucan administration induces metabolic changes and differential survival rates after bacterial or viral infection in turbot (Scophthalmus maximus). Fish Shellfish Immunol 2018;82:173-82. [PMID: 30081180 DOI: 10.1016/j.fsi.2018.08.005] [Cited by in Crossref: 10] [Cited by in F6Publishing: 7] [Article Influence: 2.5] [Reference Citation Analysis]
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37 Hernandez LF, Betancourt LR, Nakayasu ES, Ansong C, Ceballos GA, Paredes D, Abdulreda MH. Integrated Metabolomics and Proteomics Analyses in the Local Milieu of Islet Allografts in Rejection versus Tolerance. Int J Mol Sci 2021;22:8754. [PMID: 34445459 DOI: 10.3390/ijms22168754] [Reference Citation Analysis]
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39 Jung CJ, Iyengar S, Blahnik KR, Ajuha TP, Jiang JX, Farnham PJ, Zern M. Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation. PLoS One. 2011;6:e27740. [PMID: 22140464 DOI: 10.1371/journal.pone.0027740] [Cited by in Crossref: 40] [Cited by in F6Publishing: 45] [Article Influence: 3.6] [Reference Citation Analysis]
40 Nciri R, Bourogaa E, Jbahi S, Allagui MS, Elfeki A, Vincent C, Croute F. Chronic neuroprotective effects of low concentration lithium on SH-SY5Y cells: possible involvement of stress proteins and gene expression. Neural Regen Res 2014;9:735-40. [PMID: 25206881 DOI: 10.4103/1673-5374.131578] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 1.1] [Reference Citation Analysis]
41 Goldberg MS, Sharp PA. Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression. J Exp Med 2012;209:217-24. [PMID: 22271574 DOI: 10.1084/jem.20111487] [Cited by in Crossref: 149] [Cited by in F6Publishing: 144] [Article Influence: 14.9] [Reference Citation Analysis]
42 Obacz J, Pastorekova S, Vojtesek B, Hrstka R. Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses. Mol Cancer 2013;12:93. [PMID: 23945296 DOI: 10.1186/1476-4598-12-93] [Cited by in Crossref: 41] [Cited by in F6Publishing: 40] [Article Influence: 4.6] [Reference Citation Analysis]
43 Yu Z, Zhao X, Huang L, Zhang T, Yang F, Xie L, Song S, Miao P, Zhao L, Sun X, Liu J, Huang G. Proviral insertion in murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase M2 (PKM2) and promotes glycolysis in cancer cells. J Biol Chem 2013;288:35406-16. [PMID: 24142698 DOI: 10.1074/jbc.M113.508226] [Cited by in Crossref: 52] [Cited by in F6Publishing: 34] [Article Influence: 5.8] [Reference Citation Analysis]
44 Xu Q, Tu J, Dou C, Zhang J, Yang L, Liu X, Lei K, Liu Z, Wang Y, Li L, Bao H, Wang J, Tu K. HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma. Mol Cancer. 2017;16:178. [PMID: 29262861 DOI: 10.1186/s12943-017-0748-y] [Cited by in Crossref: 59] [Cited by in F6Publishing: 66] [Article Influence: 11.8] [Reference Citation Analysis]