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For: Iakova P, Timchenko L, Timchenko NA. Intracellular signaling and hepatocellular carcinoma. Semin Cancer Biol. 2011;21:28-34. [PMID: 20850540 DOI: 10.1016/j.semcancer.2010.09.001] [Cited by in Crossref: 48] [Cited by in F6Publishing: 53] [Article Influence: 4.0] [Reference Citation Analysis]
Number Citing Articles
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3 Song X, Wang J, Zheng T, Song R, Liang Y, Bhatta N, Yin D, Pan S, Liu J, Jiang H, Liu L. LBH589 Inhibits proliferation and metastasis of hepatocellular carcinoma via inhibition of gankyrin/STAT3/Akt pathway. Mol Cancer. 2013;12:114. [PMID: 24093956 DOI: 10.1186/1476-4598-12-114] [Cited by in Crossref: 42] [Cited by in F6Publishing: 42] [Article Influence: 4.7] [Reference Citation Analysis]
4 Lewis K, Valanejad L, Cast A, Wright M, Wei C, Iakova P, Stock L, Karns R, Timchenko L, Timchenko N. RNA Binding Protein CUGBP1 Inhibits Liver Cancer in a Phosphorylation-Dependent Manner. Mol Cell Biol 2017;37:e00128-17. [PMID: 28559429 DOI: 10.1128/MCB.00128-17] [Cited by in Crossref: 14] [Cited by in F6Publishing: 9] [Article Influence: 2.8] [Reference Citation Analysis]
5 Wang C, Cheng L. Gankyrin as a potential therapeutic target for cancer. Invest New Drugs 2017;35:655-61. [PMID: 28527132 DOI: 10.1007/s10637-017-0474-8] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 2.4] [Reference Citation Analysis]
6 Valanejad L, Cast A, Wright M, Bissig KD, Karns R, Weirauch MT, Timchenko N. PARP1 activation increases expression of modified tumor suppressors and pathways underlying development of aggressive hepatoblastoma. Commun Biol 2018;1:67. [PMID: 30271949 DOI: 10.1038/s42003-018-0077-8] [Cited by in Crossref: 12] [Cited by in F6Publishing: 13] [Article Influence: 3.0] [Reference Citation Analysis]
7 Brito AF, Abrantes AM, Tralhão JG, Botelho MF. Targeting Hepatocellular Carcinoma: What did we Discover so Far? Oncol Rev 2016;10:302. [PMID: 27994769 DOI: 10.4081/oncol.2016.302] [Cited by in Crossref: 19] [Cited by in F6Publishing: 21] [Article Influence: 3.2] [Reference Citation Analysis]
8 Jiang Y, Jin J, Iakova P, Hernandez JC, Jawanmardi N, Sullivan E, Guo GL, Timchenko NA, Darlington GJ. Farnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice. Mech Ageing Dev 2013;134:407-15. [PMID: 24007921 DOI: 10.1016/j.mad.2013.08.003] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 1.2] [Reference Citation Analysis]
9 Loarca L, Sassi-gaha S, Artlett CM. Two α-dicarbonyls downregulate migration, invasion, and adhesion of liver cancer cells in a p53-dependent manner. Digestive and Liver Disease 2013;45:938-46. [DOI: 10.1016/j.dld.2013.05.005] [Cited by in Crossref: 22] [Cited by in F6Publishing: 21] [Article Influence: 2.4] [Reference Citation Analysis]
10 Zhu G, Tao T, Zhang D, Liu X, Qiu H, Han L, Xu Z, Xiao Y, Cheng C, Shen A. O-GlcNAcylation of histone deacetylases 1 in hepatocellular carcinoma promotes cancer progression. Glycobiology 2016;26:820-33. [DOI: 10.1093/glycob/cww025] [Cited by in Crossref: 21] [Cited by in F6Publishing: 21] [Article Influence: 3.5] [Reference Citation Analysis]
11 Zhou Q, Mao YQ, Jiang WD, Chen YR, Huang RY, Zhou XB, Wang YF, Shi Z, Wang ZS, Huang RP. Development of IGF signaling antibody arrays for the identification of hepatocellular carcinoma biomarkers. PLoS One. 2012;7:e46851. [PMID: 23071652 DOI: 10.1371/journal.pone.0046851] [Cited by in Crossref: 15] [Cited by in F6Publishing: 16] [Article Influence: 1.5] [Reference Citation Analysis]
12 Ni FB, Lin Z, Fan XH, Shi KQ, Ao JY, Wang XD, Chen RC. A novel genomic-clinicopathologic nomogram to improve prognosis prediction of hepatocellular carcinoma. Clin Chim Acta 2020;504:88-97. [PMID: 32032609 DOI: 10.1016/j.cca.2020.02.001] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 3.0] [Reference Citation Analysis]
13 Chen J, Xia H, Zhang X, Karthik S, Pratap SV, Ooi LL, Hong W, Hui KM. ECT2 regulates the Rho/ERK signalling axis to promote early recurrence in human hepatocellular carcinoma. J Hepatol. 2015;62:1287-1295. [PMID: 25617497 DOI: 10.1016/j.jhep.2015.01.014] [Cited by in Crossref: 61] [Cited by in F6Publishing: 64] [Article Influence: 8.7] [Reference Citation Analysis]
14 Mao Z, Han X, Chen D, Xu Y, Xu L, Yin L, Sun H, Qi Y, Fang L, Liu K, Peng J. Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage. Br J Pharmacol 2019;176:919-37. [PMID: 30710454 DOI: 10.1111/bph.14594] [Cited by in Crossref: 18] [Cited by in F6Publishing: 21] [Article Influence: 6.0] [Reference Citation Analysis]
15 D'Souza AM, Jiang Y, Cast A, Valanejad L, Wright M, Lewis K, Kumbaji M, Shah S, Smithrud D, Karns R, Shin S, Timchenko N. Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation. Cell Mol Gastroenterol Hepatol 2018;6:239-55. [PMID: 30109252 DOI: 10.1016/j.jcmgh.2018.05.007] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 2.3] [Reference Citation Analysis]
16 Zhao S, Zhen Y, Fu L, Gao F, Zhou X, Huang S, Zhang L. Design, synthesis and biological evaluation of benzamide derivatives as novel NTCP inhibitors that induce apoptosis in HepG2 cells. Bioorg Med Chem Lett 2019;29:126623. [PMID: 31439379 DOI: 10.1016/j.bmcl.2019.126623] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 1.3] [Reference Citation Analysis]
17 Hong IH, Lewis K, Iakova P, Jin J, Sullivan E, Jawanmardi N, Timchenko L, Timchenko N. Age-associated change of C/EBP family proteins causes severe liver injury and acceleration of liver proliferation after CCl4 treatments. J Biol Chem 2014;289:1106-18. [PMID: 24273171 DOI: 10.1074/jbc.M113.526780] [Cited by in Crossref: 22] [Cited by in F6Publishing: 17] [Article Influence: 2.4] [Reference Citation Analysis]
18 McClendon AK, Dean JL, Ertel A, Fu Z, Rivadeneira DB, Reed CA, Bourgo RJ, Witkiewicz A, Addya S, Mayhew CN. RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage. Gastroenterology. 2011;141:1439-1450. [PMID: 21704587 DOI: 10.1053/j.gastro.2011.06.046] [Cited by in Crossref: 26] [Cited by in F6Publishing: 27] [Article Influence: 2.4] [Reference Citation Analysis]
19 Marcello MA, Morari EC, Cunha LL, De Nadai Silva AC, Carraro DM, Carvalho AL, Soares FA, Vassallo J, Ward LS. P53 and expression of immunological markers may identify early stage thyroid tumors. Clin Dev Immunol 2013;2013:846584. [PMID: 24171036 DOI: 10.1155/2013/846584] [Cited by in Crossref: 7] [Cited by in F6Publishing: 10] [Article Influence: 0.8] [Reference Citation Analysis]
20 Rivlin N, Brosh R, Oren M, Rotter V. Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis. Genes Cancer. 2011;2:466-474. [PMID: 21779514 DOI: 10.1177/1947601911408889] [Cited by in Crossref: 449] [Cited by in F6Publishing: 414] [Article Influence: 40.8] [Reference Citation Analysis]
21 He C, Xu J, Zhang J, Xie D, Ye H, Xiao Z, Cai M, Xu K, Zeng Y, Li H. High expression of trimethylated histone H3 lysine 4 is associated with poor prognosis in hepatocellular carcinoma. Hum Pathol. 2012;43:1425-1435. [PMID: 22406368 DOI: 10.1016/j.humpath.2011.11.003] [Cited by in Crossref: 73] [Cited by in F6Publishing: 62] [Article Influence: 7.3] [Reference Citation Analysis]
22 Jaafar L, Podolsky RH, Dynan WS. Long-term effects of ionizing radiation on gene expression in a zebrafish model. PLoS One 2013;8:e69445. [PMID: 23936019 DOI: 10.1371/journal.pone.0069445] [Cited by in Crossref: 18] [Cited by in F6Publishing: 17] [Article Influence: 2.0] [Reference Citation Analysis]
23 Wang X, Lin Y, Zheng Y. Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration. Mol Med Rep 2020;22:2318-28. [PMID: 32705198 DOI: 10.3892/mmr.2020.11322] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
24 Zhang R, Cao Y, Bai L, Zhu C, Li R, He H, Liu Y, Wu K, Liu F, Wu J. The collagen triple helix repeat containing 1 facilitates hepatitis B virus-associated hepatocellular carcinoma progression by regulating multiple cellular factors and signal cascades. Mol Carcinog 2015;54:1554-66. [PMID: 25263696 DOI: 10.1002/mc.22229] [Cited by in Crossref: 17] [Cited by in F6Publishing: 16] [Article Influence: 2.1] [Reference Citation Analysis]
25 Chisari AN, Sancho P, Caja L, Bertran E, Fabregat I. Lack of amino acids in mouse hepatocytes in culture induces the selection of preneoplastic cells. Cellular Signalling 2012;24:325-32. [DOI: 10.1016/j.cellsig.2011.09.018] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.2] [Reference Citation Analysis]
26 Xiang ZW, Sun L, Li GH, Maharjan R, Huang JH, Li CX. Progress in the treatment of pulmonary metastases after liver transplantation for hepatocellular carcinoma. World J Hepatol 2015; 7(20): 2309-2314 [PMID: 26380655 DOI: 10.4254/wjh.v7.i20.2309] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 0.9] [Reference Citation Analysis]
27 Kim KH, Lim HJ, Kim YJ, Kim SW, Kim YS, Tian C, Park K, Park TJ, Choung YH. The oncoprotein, gankyrin, is up-regulated in middle ear cholesteatoma. Acta Otolaryngol 2014;134:238-43. [PMID: 24460153 DOI: 10.3109/00016489.2013.844362] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.4] [Reference Citation Analysis]
28 Xie HJ, Noh JH, Kim JK, Jung KH, Eun JW, Bae HJ, Kim MG, Chang YG, Lee JY, Park H, Nam SW. HDAC1 inactivation induces mitotic defect and caspase-independent autophagic cell death in liver cancer. PLoS One. 2012;7:e34265. [PMID: 22496786 DOI: 10.1371/journal.pone.0034265] [Cited by in Crossref: 67] [Cited by in F6Publishing: 65] [Article Influence: 6.7] [Reference Citation Analysis]
29 Harada K, Baba Y, Ishimoto T, Chikamoto A, Kosumi K, Hayashi H, Nitta H, Hashimoto D, Beppu T, Baba H. LINE-1 methylation level and patient prognosis in a database of 208 hepatocellular carcinomas. Ann Surg Oncol 2015;22:1280-7. [PMID: 25319577 DOI: 10.1245/s10434-014-4134-3] [Cited by in Crossref: 43] [Cited by in F6Publishing: 40] [Article Influence: 5.4] [Reference Citation Analysis]
30 Xie G, Wang X, Huang F, Zhao A, Chen W, Yan J, Zhang Y, Lei S, Ge K, Zheng X, Liu J, Su M, Liu P, Jia W. Dysregulated hepatic bile acids collaboratively promote liver carcinogenesis. Int J Cancer 2016;139:1764-75. [PMID: 27273788 DOI: 10.1002/ijc.30219] [Cited by in Crossref: 87] [Cited by in F6Publishing: 85] [Article Influence: 14.5] [Reference Citation Analysis]
31 Fu R, Qiu C, Chen H, Zhang Z, Lu M. Retinoic acid receptor-related receptor alpha (RORalpha) is a prognostic marker for hepatocellular carcinoma. Tumor Biol 2014;35:7603-10. [DOI: 10.1007/s13277-014-2007-9] [Cited by in Crossref: 19] [Cited by in F6Publishing: 17] [Article Influence: 2.4] [Reference Citation Analysis]
32 Jing H, Zhang G, Meng L, Meng Q, Mo H, Tai Y. Gradually elevated expression of Gankyrin during human hepatocarcinogenesis and its clinicopathological significance. Sci Rep 2014;4:5503. [PMID: 24999092 DOI: 10.1038/srep05503] [Cited by in Crossref: 16] [Cited by in F6Publishing: 18] [Article Influence: 2.0] [Reference Citation Analysis]
33 Sun L, Guo C, Burnett J, Pan J, Yang Z, Ran Y, Sun D. Association between expression of Carboxypeptidase 4 and stem cell markers and their clinical significance in liver cancer development. J Cancer 2017;8:111-6. [PMID: 28123604 DOI: 10.7150/jca.17060] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 1.8] [Reference Citation Analysis]
34 Aggarwal M, Saxena R, Sinclair E, Fu Y, Jacobs A, Dyba M, Wang X, Cruz I, Berry D, Kallakury B, Mueller SC, Agostino SD, Blandino G, Avantaggiati ML, Chung FL. Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth. Cell Death Differ 2016;23:1615-27. [PMID: 27258787 DOI: 10.1038/cdd.2016.48] [Cited by in Crossref: 50] [Cited by in F6Publishing: 48] [Article Influence: 8.3] [Reference Citation Analysis]
35 Li D, Zeng Z. Epigenetic regulation of histone H3 in the process of hepatocellular tumorigenesis. Biosci Rep 2019;39:BSR20191815. [PMID: 31320544 DOI: 10.1042/BSR20191815] [Cited by in Crossref: 2] [Cited by in F6Publishing: 4] [Article Influence: 0.7] [Reference Citation Analysis]
36 Li J, Xu Y, Long X, Wang W, Jiao H, Mei Z, Yin Q, Ma L, Zhou A, Wang L, Yao M, Xia Q, Chen G. Cbx4 Governs HIF-1α to Potentiate Angiogenesis of Hepatocellular Carcinoma by Its SUMO E3 Ligase Activity. Cancer Cell 2014;25:118-31. [DOI: 10.1016/j.ccr.2013.12.008] [Cited by in Crossref: 110] [Cited by in F6Publishing: 118] [Article Influence: 13.8] [Reference Citation Analysis]
37 Hong Y, Zhou L, Xie H, Wang W, Zheng S. Differences in antiproliferative effect of STAT3 inhibition in HCC cells with versus without HBV expression. Biochem Biophys Res Commun 2015;461:513-8. [PMID: 25899746 DOI: 10.1016/j.bbrc.2015.04.058] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 0.7] [Reference Citation Analysis]
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39 Fujita J, Sakurai T. The Oncoprotein Gankyrin/PSMD10 as a Target of Cancer Therapy. Adv Exp Med Biol 2019;1164:63-71. [PMID: 31576540 DOI: 10.1007/978-3-030-22254-3_5] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
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41 Matondo RB, Toussaint MJ, Govaert KM, van Vuuren LD, Nantasanti S, Nijkamp MW, Pandit SK, Tooten PC, Koster MH, Holleman K, Schot A, Gu G, Spee B, Roskams T, Rinkes IB, Schotanus B, Kranenburg O, de Bruin A. Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19+- liver cells deficient for p53 and Rb. Oncotarget 2016;7:54662-75. [PMID: 27323406 DOI: 10.18632/oncotarget.9952] [Reference Citation Analysis]
42 Kanabar D, Farrales P, Gnanamony M, Almasri J, Abo-ali EM, Otmankel Y, Shah H, Nguyen D, El Menyewi M, Dukhande VV, D'souza A, Muth A. Structural modification of the aryl sulfonate ester of cjoc42 for enhanced gankyrin binding and anti-cancer activity. Bioorganic & Medicinal Chemistry Letters 2020;30:126889. [DOI: 10.1016/j.bmcl.2019.126889] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
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44 Zhang Y, Yang B, Du Z, Bai T, Gao YT, Wang YJ, Lou C, Wang FM, Bai Y. Aberrant methylation of SPARC in human hepatocellular carcinoma and its clinical implication. World J Gastroenterol 2012; 18(17): 2043-2052 [PMID: 22563191 DOI: 10.3748/wjg.v18.i17.2043] [Cited by in CrossRef: 11] [Cited by in F6Publishing: 12] [Article Influence: 1.1] [Reference Citation Analysis]
45 Zhang BH, Yang J, Jiang L, Lyu T, Kong LX, Tan YF, Li B, Zhu YF, Xi AY, Xu X, Yan LN, Yang JY. Development and validation of a 14-gene signature for prognosis prediction in hepatocellular carcinoma. Genomics 2020;112:2763-71. [PMID: 32198063 DOI: 10.1016/j.ygeno.2020.03.013] [Cited by in Crossref: 10] [Cited by in F6Publishing: 9] [Article Influence: 5.0] [Reference Citation Analysis]
46 Zhen Y, Wu Q, Ding Y, Zhang W, Zhai Y, Lin X, Weng Y, Guo R, Zhang Y, Feng J, Lei Y, Chen J. Exogenous hydrogen sulfide promotes hepatocellular carcinoma cell growth by activating the STAT3-COX-2 signaling pathway. Oncol Lett 2018;15:6562-70. [PMID: 29725404 DOI: 10.3892/ol.2018.8154] [Cited by in Crossref: 2] [Cited by in F6Publishing: 5] [Article Influence: 0.5] [Reference Citation Analysis]
47 Vega-Benedetti AF, Saucedo CN, Zavattari P, Vanni R, Royo F, Llavero F, Zugaza JL, Parada LA. PLAGL1 gene function during hepatoma cells proliferation. Oncotarget 2018;9:32775-94. [PMID: 30214684 DOI: 10.18632/oncotarget.25996] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
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51 Liu YX, Li QZ, Cao YN, Zhang LQ. Identification of key genes and important histone modifications in hepatocellular carcinoma. Comput Struct Biotechnol J 2020;18:2657-69. [PMID: 33033585 DOI: 10.1016/j.csbj.2020.09.013] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
52 Jiang Y, Iakova P, Jin J, Sullivan E, Sharin V, Hong IH, Anakk S, Mayor A, Darlington G, Finegold M. Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer. Hepatology. 2013;57:1098-1106. [PMID: 23172628 DOI: 10.1002/hep.26146] [Cited by in Crossref: 51] [Cited by in F6Publishing: 51] [Article Influence: 5.7] [Reference Citation Analysis]
53 Valanejad L, Lewis K, Wright M, Jiang Y, D'Souza A, Karns R, Sheridan R, Gupta A, Bove K, Witte D, Geller J, Tiao G, Nelson DL, Timchenko L, Timchenko N. FXR-Gankyrin axis is involved in development of pediatric liver cancer. Carcinogenesis 2017;38:738-47. [PMID: 28535186 DOI: 10.1093/carcin/bgx050] [Cited by in Crossref: 20] [Cited by in F6Publishing: 19] [Article Influence: 4.0] [Reference Citation Analysis]