BPG is committed to discovery and dissemination of knowledge
Cited by in F6Publishing
For: Taddia L, D'Arca D, Ferrari S, Marraccini C, Severi L, Ponterini G, Assaraf YG, Marverti G, Costi MP. Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance. Drug Resist Updat. 2015;23:20-54. [PMID: 26690339 DOI: 10.1016/j.drup.2015.10.003] [Cited by in Crossref: 37] [Cited by in F6Publishing: 34] [Article Influence: 5.3] [Reference Citation Analysis]
Number Citing Articles
1 Olszewska P, Cal D, Zagórski P, Mikiciuk-olasik E. A novel trifluoromethyl 2-phosphonopyrrole analogue inhibits human cancer cell migration and growth by cell cycle arrest at G1 phase and apoptosis. European Journal of Pharmacology 2020;871:172943. [DOI: 10.1016/j.ejphar.2020.172943] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 3.0] [Reference Citation Analysis]
2 Kholodar SA, Kohen A. Noncovalent Intermediate of Thymidylate Synthase: Fact or Fiction? J Am Chem Soc 2016;138:8056-9. [PMID: 27327197 DOI: 10.1021/jacs.6b03826] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 1.8] [Reference Citation Analysis]
3 Cui Q, Wang J, Assaraf YG, Ren L, Gupta P, Wei L, Ashby CR, Yang D, Chen Z. Modulating ROS to overcome multidrug resistance in cancer. Drug Resistance Updates 2018;41:1-25. [DOI: 10.1016/j.drup.2018.11.001] [Cited by in Crossref: 155] [Cited by in F6Publishing: 154] [Article Influence: 38.8] [Reference Citation Analysis]
4 Sacchetti F, Marverti G, D'Arca D, Severi L, Maretti E, Iannuccelli V, Pacifico S, Ponterini G, Costi MP, Leo E. pH-Promoted Release of a Novel Anti-Tumour Peptide by "Stealth" Liposomes: Effect of Nanocarriers on the Drug Activity in Cis-Platinum Resistant Cancer Cells. Pharm Res 2018;35:206. [PMID: 30209680 DOI: 10.1007/s11095-018-2489-z] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 2.3] [Reference Citation Analysis]
5 Wijdeven RH, Pang B, Assaraf YG, Neefjes J. Old drugs, novel ways out: Drug resistance toward cytotoxic chemotherapeutics. Drug Resistance Updates 2016;28:65-81. [DOI: 10.1016/j.drup.2016.07.001] [Cited by in Crossref: 101] [Cited by in F6Publishing: 95] [Article Influence: 16.8] [Reference Citation Analysis]
6 Saxena P, Severi L, Santucci M, Taddia L, Ferrari S, Luciani R, Marverti G, Marraccini C, Tondi D, Mor M, Scalvini L, Vitiello S, Losi L, Fonda S, Pacifico S, Guerrini R, D’arca D, Ponterini G, Costi MP. Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth. J Med Chem 2018;61:7374-80. [DOI: 10.1021/acs.jmedchem.7b01699] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.3] [Reference Citation Analysis]
7 Amin LH, Shawer TZ, El-naggar AM, El-sehrawi HM. Design, synthesis, anticancer evaluation and docking studies of new pyrimidine derivatives as potent thymidylate synthase inhibitors. Bioorganic Chemistry 2019;91:103159. [DOI: 10.1016/j.bioorg.2019.103159] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.7] [Reference Citation Analysis]
8 Pacifico S, Santucci M, Luciani R, Saxena P, Linciano P, Ponterini G, Lauriola A, D'Arca D, Marverti G, Guerrini R, Costi MP. Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth. Molecules 2019;24:E3493. [PMID: 31561530 DOI: 10.3390/molecules24193493] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.7] [Reference Citation Analysis]
9 Pozzi C, Lopresti L, Santucci M, Costi MP, Mangani S. Evidence of Destabilization of the Human Thymidylate Synthase (hTS) Dimeric Structure Induced by the Interface Mutation Q62R. Biomolecules 2019;9:E134. [PMID: 30987202 DOI: 10.3390/biom9040134] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
10 Tang Y, Yu F, Zhang G, Yang Z, Huang F, Ding G. A Purified Serine Protease from Nereis virens and Its Impaction of Apoptosis on Human Lung Cancer Cells. Molecules 2017;22:E1123. [PMID: 28686182 DOI: 10.3390/molecules22071123] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 2.8] [Reference Citation Analysis]
11 Wan S, Liu Z, Chen Y, Mai Z, Jiang M, Di Q, Sun B. MicroRNA-140-3p represses the proliferation, migration, invasion and angiogenesis of lung adenocarcinoma cells via targeting TYMS (thymidylate synthetase). Bioengineered 2021;12:11959-77. [PMID: 34818974 DOI: 10.1080/21655979.2021.2009422] [Reference Citation Analysis]
12 Dinić J, Efferth T, García-Sosa AT, Grahovac J, Padrón JM, Pajeva I, Rizzolio F, Saponara S, Spengler G, Tsakovska I. Repurposing old drugs to fight multidrug resistant cancers. Drug Resist Updat 2020;52:100713. [PMID: 32615525 DOI: 10.1016/j.drup.2020.100713] [Cited by in Crossref: 18] [Cited by in F6Publishing: 13] [Article Influence: 9.0] [Reference Citation Analysis]
13 Sabeti Aghabozorgi A, Moradi Sarabi M, Jafarzadeh-Esfehani R, Koochakkhani S, Hassanzadeh M, Kavousipour S, Eftekhar E. Molecular determinants of response to 5-fluorouracil-based chemotherapy in colorectal cancer: The undisputable role of micro-ribonucleic acids. World J Gastrointest Oncol 2020; 12(9): 942-956 [PMID: 33005290 DOI: 10.4251/wjgo.v12.i9.942] [Cited by in CrossRef: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
14 Vitiello S, Caselli M, Pavesi G, Santucci M, Ferrari S, Paola Costi M, Ponterini G. Intrinsic Fluorescence of the Active and the Inactive Functional Forms of Human Thymidylate Synthase. Chembiochem 2021;22:1800-10. [PMID: 33554411 DOI: 10.1002/cbic.202000722] [Reference Citation Analysis]
15 Marverti G, Gozzi G, Lauriola A, Ponterini G, Belluti S, Imbriano C, Costi MP, D'Arca D. The 1,10-Phenanthroline Ligand Enhances the Antiproliferative Activity of DNA-Intercalating Thiourea-Pd(II) and -Pt(II) Complexes Against Cisplatin-Sensitive and -Resistant Human Ovarian Cancer Cell Lines. Int J Mol Sci 2019;20:E6122. [PMID: 31817267 DOI: 10.3390/ijms20246122] [Cited by in Crossref: 1] [Article Influence: 0.3] [Reference Citation Analysis]
16 Ponterini G, Martello A, Pavesi G, Lauriola A, Luciani R, Santucci M, Pelà M, Gozzi G, Pacifico S, Guerrini R, Marverti G, Costi MP, D'Arca D. Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology. Sci Rep 2016;6:27198. [PMID: 27250901 DOI: 10.1038/srep27198] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 1.5] [Reference Citation Analysis]
17 Marverti G, Marraccini C, Martello A, D'Arca D, Pacifico S, Guerrini R, Spyrakis F, Gozzi G, Lauriola A, Santucci M, Cannazza G, Tagliazucchi L, Cazzato AS, Losi L, Ferrari S, Ponterini G, Costi MP. Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting. J Med Chem 2021;64:3204-21. [PMID: 33710891 DOI: 10.1021/acs.jmedchem.0c02107] [Reference Citation Analysis]
18 Marverti G, Gozzi G, Maretti E, Lauriola A, Severi L, Sacchetti F, Losi L, Pacifico S, Ferrari S, Ponterini G, Leo E, Costi MP, D'Arca D. A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells. Int J Mol Sci 2020;21:E4452. [PMID: 32585842 DOI: 10.3390/ijms21124452] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
19 Islam Z, Gurevic I, Strutzenberg TS, Ghosh AK, Iqbal T, Kohen A. Bacterial versus human thymidylate synthase: Kinetics and functionality. PLoS One 2018;13:e0196506. [PMID: 29715278 DOI: 10.1371/journal.pone.0196506] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
20 Maj P, Mori M, Sobich J, Markowicz J, Uram Ł, Zieliński Z, Quaglio D, Calcaterra A, Cau Y, Botta B, Rode W. Alvaxanthone, a Thymidylate Synthase Inhibitor with Nematocidal and Tumoricidal Activities. Molecules 2020;25:E2894. [PMID: 32586022 DOI: 10.3390/molecules25122894] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
21 Siddiqui A, Ceppi P. A non-proliferative role of pyrimidine metabolism in cancer. Mol Metab 2020;35:100962. [PMID: 32244187 DOI: 10.1016/j.molmet.2020.02.005] [Cited by in Crossref: 13] [Cited by in F6Publishing: 11] [Article Influence: 6.5] [Reference Citation Analysis]
22 Pan X, Zhao YQ, Hu FY, Chi CF, Wang B. Anticancer Activity of a Hexapeptide from Skate (Raja porosa) Cartilage Protein Hydrolysate in HeLa Cells. Mar Drugs 2016;14:E153. [PMID: 27537897 DOI: 10.3390/md14080153] [Cited by in Crossref: 35] [Cited by in F6Publishing: 30] [Article Influence: 5.8] [Reference Citation Analysis]
23 Borsari C, Ferrari S, Venturelli A, Costi MP. Target-based approaches for the discovery of new antimycobacterial drugs. Drug Discovery Today 2017;22:576-84. [DOI: 10.1016/j.drudis.2016.11.014] [Cited by in Crossref: 17] [Cited by in F6Publishing: 14] [Article Influence: 3.4] [Reference Citation Analysis]
24 Sacchetti F, D'arca D, Genovese F, Pacifico S, Maretti E, Hanuskova M, Iannuccelli V, Costi MP, Leo E. Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones? Drug Development and Industrial Pharmacy 2017;43:465-73. [DOI: 10.1080/03639045.2016.1262870] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.2] [Reference Citation Analysis]
25 Jarmuła A, Wilk P, Maj P, Ludwiczak J, Dowierciał A, Banaszak K, Rypniewski W, Cieśla J, Dąbrowska M, Frączyk T, Bronowska AK, Jakowiecki J, Filipek S, Rode W. Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS. J Mol Graph Model 2017;77:33-50. [PMID: 28826032 DOI: 10.1016/j.jmgm.2017.08.008] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.4] [Reference Citation Analysis]
26 Tyng V, Kellman ME. Kinetic Model of Translational Autoregulation. J Phys Chem B 2019;123:369-78. [DOI: 10.1021/acs.jpcb.8b09503] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
27 Mondal D, Koehn EM, Yao J, Wiemer DF, Kohen A. Chemo-enzymatic synthesis of the exocyclic olefin isomer of thymidine monophosphate. Bioorg Med Chem 2018;26:2365-71. [PMID: 29606487 DOI: 10.1016/j.bmc.2018.03.032] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
28 Severi L, Losi L, Fonda S, Taddia L, Gozzi G, Marverti G, Magni F, Chinello C, Stella M, Sheouli J, Braicu EI, Genovese F, Lauriola A, Marraccini C, Gualandi A, D'Arca D, Ferrari S, Costi MP. Proteomic and Bioinformatic Studies for the Characterization of Response to Pemetrexed in Platinum Drug Resistant Ovarian Cancer. Front Pharmacol 2018;9:454. [PMID: 29867465 DOI: 10.3389/fphar.2018.00454] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 1.5] [Reference Citation Analysis]
29 Yan L, Lin M, Pan S, Assaraf YG, Wang ZW, Zhu X. Emerging roles of F-box proteins in cancer drug resistance. Drug Resist Updat 2020;49:100673. [PMID: 31877405 DOI: 10.1016/j.drup.2019.100673] [Cited by in Crossref: 14] [Cited by in F6Publishing: 16] [Article Influence: 4.7] [Reference Citation Analysis]
30 Pozzi C, Santucci M, Marverti G, D'Arca D, Tagliazucchi L, Ferrari S, Gozzi G, Losi L, Tassone G, Mangani S, Ponterini G, Costi MP. Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations. Cancers (Basel) 2021;13:2061. [PMID: 33923290 DOI: 10.3390/cancers13092061] [Reference Citation Analysis]
31 Stark M, Assaraf YG. Structural recognition of tubulysin B derivatives by multidrug resistance efflux transporters in human cancer cells. Oncotarget 2017;8:49973-87. [PMID: 28637003 DOI: 10.18632/oncotarget.18385] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
32 Sapienza PJ, Popov KI, Mowrey DD, Falk BT, Dokholyan NV, Lee AL. Inter-Active Site Communication Mediated by the Dimer Interface β-Sheet in the Half-the-Sites Enzyme, Thymidylate Synthase. Biochemistry 2019;58:3302-13. [PMID: 31283187 DOI: 10.1021/acs.biochem.9b00486] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
33 Maj P, Jarmuła A, Wilk P, Prokopowicz M, Rypniewski W, Zieliński Z, Dowierciał A, Bzowska A, Rode W. Molecular Mechanism of Thymidylate Synthase Inhibition by N4-Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies. Int J Mol Sci 2021;22:4758. [PMID: 33946210 DOI: 10.3390/ijms22094758] [Reference Citation Analysis]
34 Chen Y, Tang Y, Tang Y, Yang Z, Ding G. Serine Protease from Nereis virens Inhibits H1299 Lung Cancer Cell Proliferation via the PI3K/AKT/mTOR Pathway. Mar Drugs 2019;17:E366. [PMID: 31226829 DOI: 10.3390/md17060366] [Cited by in Crossref: 3] [Cited by in F6Publishing: 5] [Article Influence: 1.0] [Reference Citation Analysis]
35 Ludwiczak J, Maj P, Wilk P, Frączyk T, Ruman T, Kierdaszuk B, Jarmuła A, Rode W. Phosphorylation of thymidylate synthase affects slow-binding inhibition by 5-fluoro-dUMP and N(4)-hydroxy-dCMP. Mol Biosyst 2016;12:1333-41. [PMID: 26916840 DOI: 10.1039/c6mb00026f] [Cited by in Crossref: 9] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]