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For: Mohan S, Dhanalakshmi S, Mallikarjuna GU, Singh RP, Agarwal R. Silibinin modulates UVB-induced apoptosis via mitochondrial proteins, caspases activation, and mitogen-activated protein kinase signaling in human epidermoid carcinoma A431 cells. Biochem Biophys Res Commun. 2004;320:183-189. [PMID: 15207719 DOI: 10.1016/j.bbrc.2004.05.153] [Cited by in Crossref: 36] [Cited by in F6Publishing: 33] [Article Influence: 2.0] [Reference Citation Analysis]
Number Citing Articles
1 Flaig TW, Su LJ, Harrison G, Agarwal R, Glodé LM. Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells. Int J Cancer 2007;120:2028-33. [PMID: 17230508 DOI: 10.1002/ijc.22465] [Cited by in Crossref: 35] [Cited by in F6Publishing: 28] [Article Influence: 2.3] [Reference Citation Analysis]
2 Křen V, Walterová D. Silybin and silymarin - new effects and applications. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2005;149:29-41. [DOI: 10.5507/bp.2005.002] [Cited by in Crossref: 236] [Cited by in F6Publishing: 146] [Article Influence: 13.9] [Reference Citation Analysis]
3 Anwar A, Anwar H, Yamauchi T, Tseng R, Agarwal R, Horwitz LD, Zhai Z, Fujita M. Bucillamine Inhibits UVB-Induced MAPK Activation and Apoptosis in Human HaCaT Keratinocytes and SKH-1 Hairless Mouse Skin. Photochem Photobiol 2020;96:870-6. [PMID: 32077107 DOI: 10.1111/php.13228] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
4 Segreto HR, Oshima CT, Franco MF, Silva MR, Egami MI, Teixeira VP, Segreto RA. Phosphorylation and cytoplasmic localization of MAPK p38 during apoptosis signaling in bone marrow granulocytes of mice irradiated in vivo and the role of amifostine in reducing these effects. Acta Histochem 2011;113:300-7. [PMID: 20074782 DOI: 10.1016/j.acthis.2009.12.002] [Cited by in Crossref: 9] [Cited by in F6Publishing: 7] [Article Influence: 0.8] [Reference Citation Analysis]
5 Mashhadi Akbar Boojar M, Mashhadi Akbar Boojar M, Golmohammad S. Overview of Silibinin anti-tumor effects. Journal of Herbal Medicine 2020;23:100375. [DOI: 10.1016/j.hermed.2020.100375] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 1.5] [Reference Citation Analysis]
6 Kumar R, Deep G, Agarwal R. An Overview of Ultraviolet B Radiation-Induced Skin Cancer Chemoprevention by Silibinin. Curr Pharmacol Rep 2015;1:206-15. [PMID: 26097804 DOI: 10.1007/s40495-015-0027-9] [Cited by in Crossref: 31] [Cited by in F6Publishing: 20] [Article Influence: 4.4] [Reference Citation Analysis]
7 Gu HR, Park SC, Choi SJ, Lee JC, Kim YC, Han CJ, Kim J, Yang KY, Kim YJ, Noh GY, No SH, Jeong JH. Combined treatment with silibinin and either sorafenib or gefitinib enhances their growth-inhibiting effects in hepatocellular carcinoma cells. Clin Mol Hepatol 2015;21:49-59. [PMID: 25834802 DOI: 10.3350/cmh.2015.21.1.49] [Cited by in Crossref: 23] [Cited by in F6Publishing: 19] [Article Influence: 3.3] [Reference Citation Analysis]
8 Deep G, Agarwal R. Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer. Cancer Metastasis Rev 2010;29:447-63. [PMID: 20714788 DOI: 10.1007/s10555-010-9237-0] [Cited by in Crossref: 149] [Cited by in F6Publishing: 129] [Article Influence: 12.4] [Reference Citation Analysis]
9 Dhanalakshmi S, Agarwal C, Singh RP, Agarwal R. Silibinin Up-regulates DNA-Protein Kinase-dependent p53 Activation to Enhance UVB-induced Apoptosis in Mouse Epithelial JB6 Cells. Journal of Biological Chemistry 2005;280:20375-83. [DOI: 10.1074/jbc.m414640200] [Cited by in Crossref: 46] [Cited by in F6Publishing: 21] [Article Influence: 2.7] [Reference Citation Analysis]
10 Kuen CY, Fakurazi S, Othman SS, Masarudin MJ. Increased Loading, Efficacy and Sustained Release of Silibinin, a Poorly Soluble Drug Using Hydrophobically-Modified Chitosan Nanoparticles for Enhanced Delivery of Anticancer Drug Delivery Systems. Nanomaterials (Basel) 2017;7:E379. [PMID: 29117121 DOI: 10.3390/nano7110379] [Cited by in Crossref: 19] [Cited by in F6Publishing: 15] [Article Influence: 3.8] [Reference Citation Analysis]
11 Palaniyandi K, Wang S, Chen F. Chinese Medicinal Herbs as Source of Rational Anticancer Therapy. In: Tsay H, Shyur L, Agrawal DC, Wu Y, Wang S, editors. Medicinal Plants - Recent Advances in Research and Development. Singapore: Springer; 2016. pp. 327-62. [DOI: 10.1007/978-981-10-1085-9_14] [Cited by in Crossref: 2] [Article Influence: 0.3] [Reference Citation Analysis]
12 Liou W, Chen L, Niu H, Yang T, Cheng J, Lin K. Herbal product silibinin-induced programmed cell death is enhanced by metformin in cervical cancer cells at the dose without influence on nonmalignant cells. J Appl Biomed 2015;13:113-21. [DOI: 10.1016/j.jab.2014.11.001] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 0.7] [Reference Citation Analysis]
13 Ham J, Lim W, Bazer FW, Song G. Silibinin stimluates apoptosis by inducing generation of ROS and ER stress in human choriocarcinoma cells. J Cell Physiol 2018;233:1638-49. [PMID: 28657208 DOI: 10.1002/jcp.26069] [Cited by in Crossref: 17] [Cited by in F6Publishing: 18] [Article Influence: 3.4] [Reference Citation Analysis]
14 Chen P, Hsieh Y, Chiou H, Chu S. Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways. Chemico-Biological Interactions 2005;156:141-50. [DOI: 10.1016/j.cbi.2005.08.005] [Cited by in Crossref: 141] [Cited by in F6Publishing: 132] [Article Influence: 8.3] [Reference Citation Analysis]
15 Noh EM, Yi MS, Youn HJ, Lee BK, Lee YR, Han JH, Yu HN, Kim JS, Jung SH. Silibinin enhances ultraviolet B-induced apoptosis in mcf-7 human breast cancer cells. J Breast Cancer 2011;14:8-13. [PMID: 21847388 DOI: 10.4048/jbc.2011.14.1.8] [Cited by in Crossref: 17] [Cited by in F6Publishing: 18] [Article Influence: 1.5] [Reference Citation Analysis]
16 Svobodová A, Zdarilová A, Walterová D, Vostálová J. Flavonolignans from Silybum marianum moderate UVA-induced oxidative damage to HaCaT keratinocytes. J Dermatol Sci. 2007;48:213-224. [PMID: 17689055 DOI: 10.1016/j.jdermsci.2007.06.008] [Cited by in Crossref: 52] [Cited by in F6Publishing: 47] [Article Influence: 3.5] [Reference Citation Analysis]
17 Dheeraj A, Rigby CM, O'Bryant CL, Agarwal C, Singh RP, Deep G, Agarwal R. Silibinin Treatment Inhibits the Growth of Hedgehog Inhibitor-Resistant Basal Cell Carcinoma Cells via Targeting EGFR-MAPK-Akt and Hedgehog Signaling. Photochem Photobiol 2017;93:999-1007. [PMID: 28120452 DOI: 10.1111/php.12727] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 3.2] [Reference Citation Analysis]
18 Esmaeil N, Anaraki SB, Gharagozloo M, Moayedi B. Silymarin impacts on immune system as an immunomodulator: One key for many locks. International Immunopharmacology 2017;50:194-201. [DOI: 10.1016/j.intimp.2017.06.030] [Cited by in Crossref: 38] [Cited by in F6Publishing: 31] [Article Influence: 7.6] [Reference Citation Analysis]
19 Bayram D, Çetin E, Kara M, Özgöçmen M, Candan I. The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells. Hum Exp Toxicol 2017;36:573-86. [DOI: 10.1177/0960327116658105] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.2] [Reference Citation Analysis]
20 Mateen S, Tyagi A, Agarwal C, Singh RP, Agarwal R. Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators. Mol Carcinog. 2010;49:247-258. [PMID: 19908243 DOI: 10.1002/mc.20595] [Cited by in Crossref: 54] [Cited by in F6Publishing: 56] [Article Influence: 4.5] [Reference Citation Analysis]
21 Deep G, Agarwal R. Chemopreventive Efficacy of Silymarin in Skin and Prostate Cancer. Integr Cancer Ther 2007;6:130-45. [DOI: 10.1177/1534735407301441] [Cited by in Crossref: 80] [Cited by in F6Publishing: 65] [Article Influence: 13.3] [Reference Citation Analysis]
22 Lah JJ, Cui W, Hu KQ. Effects and mechanisms of silibinin on human hepatoma cell lines. World J Gastroenterol 2007; 13(40): 5299-5305 [PMID: 17879397 DOI: 10.3748/wjg.v13.i40.5299] [Cited by in CrossRef: 65] [Cited by in F6Publishing: 60] [Article Influence: 4.3] [Reference Citation Analysis]
23 LaBarbera DV, Modzelewska K, Glazar AI, Gray PD, Kaur M, Liu T, Grossman D, Harper MK, Kuwada SK, Moghal N, Ireland CM. The marine alkaloid naamidine A promotes caspase-dependent apoptosis in tumor cells. Anticancer Drugs 2009;20:425-36. [PMID: 19369860 DOI: 10.1097/CAD.0b013e32832ae55f] [Cited by in Crossref: 33] [Cited by in F6Publishing: 13] [Article Influence: 2.8] [Reference Citation Analysis]
24 Antherieu S, Ledirac N, Luzy AP, Lenormand P, Caron JC, Rahmani R. Endosulfan decreases cell growth and apoptosis in human HaCaT keratinocytes: partial ROS-dependent ERK1/2 mechanism. J Cell Physiol 2007;213:177-86. [PMID: 17503468 DOI: 10.1002/jcp.21108] [Cited by in Crossref: 30] [Cited by in F6Publishing: 29] [Article Influence: 2.0] [Reference Citation Analysis]
25 Zhang Y, Yang DH, Zhang YT, Chen XM, Li LL, Cai SQ. Biotransformation on the flavonolignan constituents of Silybi Fructus by an intestinal bacterial strain Eubacterium limosum ZL-II. Fitoterapia 2014;92:61-71. [PMID: 24125915 DOI: 10.1016/j.fitote.2013.10.001] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 0.9] [Reference Citation Analysis]
26 Lee SO, Jeong YJ, Im HG, Kim CH, Chang YC, Lee IS. Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells. Biochem Biophys Res Commun 2007;354:165-71. [PMID: 17214970 DOI: 10.1016/j.bbrc.2006.12.181] [Cited by in Crossref: 80] [Cited by in F6Publishing: 70] [Article Influence: 5.3] [Reference Citation Analysis]
27 Lee JS, Kim SG, Kim HK, Lee TH, Jeong YI, Lee CM, Yoon MS, Na YJ, Suh DS, Park NC, Choi IH, Kim GY, Choi YH, Chung HY, Park YM. Silibinin polarizes Th1/Th2 immune responses through the inhibition of immunostimulatory function of dendritic cells. J Cell Physiol 2007;210:385-97. [PMID: 17058260 DOI: 10.1002/jcp.20852] [Cited by in Crossref: 37] [Cited by in F6Publishing: 36] [Article Influence: 2.5] [Reference Citation Analysis]
28 Tsai CC, Chuang TW, Chen LJ, Niu HS, Chung KM, Cheng JT, Lin KC. Increase in apoptosis by combination of metformin with silibinin in human colorectal cancer cells. World J Gastroenterol 2015; 21(14): 4169-4177 [PMID: 25892866 DOI: 10.3748/wjg.v21.i14.4169] [Cited by in CrossRef: 30] [Cited by in F6Publishing: 24] [Article Influence: 4.3] [Reference Citation Analysis]
29 Dvořák Z, Vrzal R, Ulrichová J. Silybin and dehydrosilybin inhibit cytochrome P450 1A1 catalytic activity: A study in human keratinocytes and human hepatoma cells. Cell Biol Toxicol 2006;22:81-90. [DOI: 10.1007/s10565-006-0017-0] [Cited by in Crossref: 16] [Cited by in F6Publishing: 16] [Article Influence: 1.0] [Reference Citation Analysis]
30 Momeny M, Khorramizadeh MR, Ghaffari SH, Yousefi M, Yekaninejad MS, Esmaeili R, Jahanshiri Z, Nooridaloii MR. Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation. European Journal of Pharmacology 2008;591:13-20. [DOI: 10.1016/j.ejphar.2008.06.011] [Cited by in Crossref: 40] [Cited by in F6Publishing: 42] [Article Influence: 2.9] [Reference Citation Analysis]
31 Roy P, Madan E, Kalra N, Nigam N, George J, Ray RS, Hans RK, Prasad S, Shukla Y. Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-kappaB pathway in human epidermoid carcinoma A431 cells. Biochem Biophys Res Commun 2009;384:215-20. [PMID: 19397895 DOI: 10.1016/j.bbrc.2009.04.100] [Cited by in Crossref: 27] [Cited by in F6Publishing: 24] [Article Influence: 2.1] [Reference Citation Analysis]
32 Lao CD, Demierre M, Sondak VK. Targeting events in melanoma carcinogenesis for the prevention of melanoma. Expert Review of Anticancer Therapy 2014;6:1559-68. [DOI: 10.1586/14737140.6.11.1559] [Cited by in Crossref: 46] [Cited by in F6Publishing: 38] [Article Influence: 5.8] [Reference Citation Analysis]
33 Li L, Gao Y, Zhang L, Zeng J, He D, Sun Y. Silibinin inhibits cell growth and induces apoptosis by caspase activation, down-regulating survivin and blocking EGFR–ERK activation in renal cell carcinoma. Cancer Letters 2008;272:61-9. [DOI: 10.1016/j.canlet.2008.06.033] [Cited by in Crossref: 62] [Cited by in F6Publishing: 45] [Article Influence: 4.4] [Reference Citation Analysis]
34 Chang HR, Chen PN, Yang SF, Sun YS, Wu SW, Hung TW, Lian JD, Chu SC, Hsieh YS. Silibinin inhibits the invasion and migration of renal carcinoma 786-O cells in vitro, inhibits the growth of xenografts in vivo and enhances chemosensitivity to 5-fluorouracil and paclitaxel. Mol Carcinog 2011;50:811-23. [PMID: 21574189 DOI: 10.1002/mc.20756] [Cited by in Crossref: 30] [Cited by in F6Publishing: 26] [Article Influence: 2.7] [Reference Citation Analysis]