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For: Kontoghiorghe CN, Andreou N, Constantinou K, Kontoghiorghes GJ. World health dilemmas: Orphan and rare diseases, orphan drugs and orphan patients. World J Methodol 2014; 4(3): 163-188 [PMID: 25332915 DOI: 10.5662/wjm.v4.i3.163]
URL: https://www.wjgnet.com/1007-9327/full/v4/i3/163.htm
Number Citing Articles
1
George Kontoghiorghes, Annita Kolnagou, Theodora Demetriou, Marina Neocleous, Christina Kontoghiorghe. New Era in the Treatment of Iron Deficiency Anaemia Using Trimaltol Iron and Other Lipophilic Iron Chelator Complexes: Historical Perspectives of Discovery and Future ApplicationsInternational Journal of Molecular Sciences 2021; 22(11): 5546 doi: 10.3390/ijms22115546
2
David J Timson. Value of predictive bioinformatics in inherited metabolic diseasesWorld Journal of Medical Genetics 2015; 5(3): 46-51 doi: 10.5496/wjmg.v5.i3.46
3
Davide Benedetto Tiz, Luana Bagnoli, Ornelio Rosati, Francesca Marini, Luca Sancineto, Claudio Santi. Top Selling (2026) Small Molecule Orphan Drugs: A Journey into Their ChemistryInternational Journal of Molecular Sciences 2023; 24(2): 930 doi: 10.3390/ijms24020930
4
Ekaterina V Makarova, Ivan S Krysanov, Tatiana P Valilyeva, Mikhail D Vasiliev, Rena A Zinchenko. Evaluation of orphan diseases global burdenEuropean Journal of Translational Myology 2021; 31(2) doi: 10.4081/ejtm.2021.9610
5
George J. Kontoghiorghes. Differences between the European Union and United States of America in Drug Regulatory Affairs Affect Global Patient Safety Standards and Public Health Awareness: The Case of Deferasirox and Other Iron Chelating DrugsMedicines 2021; 8(7): 36 doi: 10.3390/medicines8070036
6
Bander Balkhi, Asma Almuaither, Saeed Alqahtani. Cross-national comparative study of orphan drug policies in Saudi Arabia, the United States, and the European UnionSaudi Pharmaceutical Journal 2023; 31(9): 101738 doi: 10.1016/j.jsps.2023.101738
7
George J. Kontoghiorghes, Annita Kolnagou, Stella Fetta, Christina N. Kontoghiorghe. Conventional and Unconventional Approaches for Innovative Drug Treatments in COVID-19: Looking Outside of Plato’s CaveInternational Journal of Molecular Sciences 2021; 22(13): 7208 doi: 10.3390/ijms22137208
8
Paloma López Villafranca. Communicating Rare Diseases and Disorders in the Digital AgeAdvances in Medical Technologies and Clinical Practice 2020; : 200 doi: 10.4018/978-1-7998-2088-8.ch006
9
Matthew K. Ito, Gerald F. Watts. Challenges in the Diagnosis and Treatment of Homozygous Familial HypercholesterolemiaDrugs 2015; 75(15): 1715 doi: 10.1007/s40265-015-0466-y
10
Yuna Horiuchi, Ryunosuke Ohkawa, Shao-Jui Lai, Azusa Yamazaki, Hayato Ikoma, Kouji Yano, Takahiro Kameda, Minoru Tozuka. Characterization of the cholesterol efflux of apolipoprotein E-containing high-density lipoprotein in THP-1 cellsBiological Chemistry 2019; 400(2): 209 doi: 10.1515/hsz-2018-0284
11
Christina N Kontoghiorghe, George J Kontoghiorghes. New developments and controversies in iron metabolism and iron chelation therapyWorld Journal of Methodology 2016; 6(1): 1-19 doi: 10.5662/wjm.v6.i1.1
12
Inés Adriana Cismondi, Romina Kohan, Heather Adams, Mike Bond, Rachel Brown, Jonathan D. Cooper, Perla K. de Hidalgo, Sophia-Martha Kleine Holthaus, Sara E. Mole, Julia Mugnaini, Ana María Oller de Ramirez, Favio Pesaola, Gisela Rautenberg, Frances M. Platt, Inés Noher de Halac. Guidelines for incorporating scientific knowledge and practice on rare diseases into higher education: neuronal ceroid lipofuscinoses as a model disorderBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2015; 1852(10): 2316 doi: 10.1016/j.bbadis.2015.06.018
13
Christina Kontoghiorghe, Annita Kolnagou, George Kontoghiorghes. Phytochelators Intended for Clinical Use in Iron Overload, Other Diseases of Iron Imbalance and Free Radical PathologyMolecules 2015; 20(11): 20841 doi: 10.3390/molecules201119725
14
George J. Kontoghiorghes, Annita Kolnagou, Christina N. Kontoghiorghe. Post COVID-19 Reflections and Questions: How Prepared Are We for the Next Pandemic?International Journal of Molecular Sciences 2024; 25(2): 859 doi: 10.3390/ijms25020859
15
George J. Kontoghiorghes. New Iron Metabolic Pathways and Chelation Targeting Strategies Affecting the Treatment of All Types and Stages of CancerInternational Journal of Molecular Sciences 2022; 23(22): 13990 doi: 10.3390/ijms232213990
16
George J. Kontoghiorghes. Drug Selection and Posology, Optimal Therapies and Risk/Benefit Assessment in Medicine: The Paradigm of Iron-Chelating DrugsInternational Journal of Molecular Sciences 2023; 24(23): 16749 doi: 10.3390/ijms242316749
17
George J. Kontoghiorghes. The Vital Role Played by Deferiprone in the Transition of Thalassaemia from a Fatal to a Chronic Disease and Challenges in Its Repurposing for Use in Non-Iron-Loaded DiseasesPharmaceuticals 2023; 16(7): 1016 doi: 10.3390/ph16071016
18
Yuna Horiuchi, Ryunosuke Ohkawa, Shao-Jui Lai, Shitsuko Shimano, Michio Hagihara, Shuji Tohda, Takahiro Kameda, Minoru Tozuka. Usefulness of apolipoprotein B-depleted serum in cholesterol efflux capacity assays using immobilized liposome-bound gel beadsBioscience Reports 2019; 39(4) doi: 10.1042/BSR20190213
19
George J. Kontoghiorghes. Ethics in Medicines: Exposing Unethical Practices and Corruption in All Sectors of Medicines Is Essential for Improving Global Public Health and Saving Patients’ LivesMedicines 2021; 8(9): 54 doi: 10.3390/medicines8090054
20
George J. Kontoghiorghes. Deferiprone: A Forty-Year-Old Multi-Targeting Drug with Possible Activity against COVID-19 and Diseases of Similar SymptomatologyInternational Journal of Molecular Sciences 2022; 23(12): 6735 doi: 10.3390/ijms23126735
21
Gema Esteban-Bueno, Lucas Ramón Díaz-Anadón, Antonio Rodríguez González, Miguel Navarro Cabrero, Aída María Berenguel Hernández. Protocolo genético en Atención Primaria para enfermedades raras: el síndrome de Wolfram como prototipoAtención Primaria 2022; 54(5): 102285 doi: 10.1016/j.aprim.2022.102285
22
Jian Qian, Bradley P. Sullivan, Samuel J. Peterson, Cory Berkland. Nonabsorbable Iron Binding Polymers Prevent Dietary Iron Absorption for the Treatment of Iron OverloadACS Macro Letters 2017; 6(4): 350 doi: 10.1021/acsmacrolett.6b00945
23
George J. Kontoghiorghes, Annita Kolnagou, Christina N. Kontoghiorghe, Loukia Mourouzidis, Viktor A. Timoshnikov, Nikolay E. Polyakov. Trying to Solve the Puzzle of the Interaction of Ascorbic Acid and Iron: Redox, Chelation and Therapeutic ImplicationsMedicines 2020; 7(8): 45 doi: 10.3390/medicines7080045
24
Hala A. Al-Kherbash, Ahmed Al-Awdi, Nawal S. Hasan. Pattern and clinical profile of thalassemia among pediatric patients attending the Yemeni Society Centers for Thalassemia and Genetic Blood Disorders in YemenThe Scientific Journal of Al-Azhar Medical Faculty, Girls 2017; 1(2): 43 doi: 10.4103/sjamf.sjamf_15_17
25
Sara Rosenberg, Björn Södergård, Jessica M. Rosenholm, Jussi-Pekka Rauha. A qualitative study on the views of experts on the social impact of the high-priced orphan drug nusinersenExploratory Research in Clinical and Social Pharmacy 2023; 9: 100227 doi: 10.1016/j.rcsop.2023.100227
26
George Kontoghiorghes, Christina Kontoghiorghe. Iron and Chelation in Biochemistry and Medicine: New Approaches to Controlling Iron Metabolism and Treating Related DiseasesCells 2020; 9(6): 1456 doi: 10.3390/cells9061456
27
George J Kontoghiorghes, Christina N Kontoghiorghe. Prospects for the introduction of targeted antioxidant drugs for the prevention and treatment of diseases related to free radical pathologyExpert Opinion on Investigational Drugs 2019; 28(7): 593 doi: 10.1080/13543784.2019.1631284
28
George J. Kontoghiorghes. Questioning Established Theories and Treatment Methods Related to Iron and Other Metal Metabolic Changes, Affecting All Major Diseases and Billions of PatientsInternational Journal of Molecular Sciences 2022; 23(3): 1364 doi: 10.3390/ijms23031364
29
George J. Kontoghiorghes. Deferiprone and Iron–Maltol: Forty Years since Their Discovery and Insights into Their Drug Design, Development, Clinical Use and Future ProspectsInternational Journal of Molecular Sciences 2023; 24(5): 4970 doi: 10.3390/ijms24054970
30
Paloma López Villafranca. Research Anthology on Improving Health Literacy Through Patient Communication and Mass Media2022; : 163 doi: 10.4018/978-1-6684-2414-8.ch010