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For: Dai N, Yu YC, Ren TH, Wu JG, Jiang Y, Shen LG, Zhang J. Gynura root induces hepatic veno-occlusive disease: A case report and review of the literature. World J Gastroenterol 2007; 13(10): 1628-1631 [PMID: 17461462 DOI: 10.3748/wjg.v13.i10.1628]
URL: https://www.wjgnet.com/1007-9327/full/v13/i10/1628.htm
Number Citing Articles
1
Pengcheng Ou, Xinyu Liu, Zhiqun Tang, Zhouhua Hou, Li Liu, Jun Liu, Shangchen Zhou, Zhixiong Fang, Kewei Sun, Yue Chen, Xiaobei Chen, Yi Li, Jun Chen. Gynura Segetum Related Hepatic Sinusoidal Obstruction Syndrome: A Liver Disease with High Mortality and Misdiagnosis RateCurrent Pharmaceutical Design 2019; 25(35): 3762 doi: 10.2174/1381612825666191007162024
2
Harshad Devarbhavi, Guruprasad Aithal, Sombat Treeprasertsuk, Hajime Takikawa, Yimin Mao, Saggere M. Shasthry, Saeed Hamid, Soek Siam Tan, Cyriac Abby Philips, Jacob George, Wasim Jafri, Shiv K. Sarin. Drug-induced liver injury: Asia Pacific Association of Study of Liver consensus guidelinesHepatology International 2021; 15(2): 258 doi: 10.1007/s12072-021-10144-3
3
Na Li, Fan Zhang, Wei Lian, Huali Wang, Jiang Zheng, Ge Lin. Immunoassay approach for diagnosis of exposure to pyrrolizidine alkaloidsJournal of Environmental Science and Health, Part C 2017; 35(3): 127 doi: 10.1080/10590501.2017.1328828
4
Xueyong Qi, Shufang Wang, Bin Wu, Haibin Qu. Determination of Hepatotoxic Pyrrolizidine Alkaloids in Gynura segetum by MEKCChromatographia 2009; 70(1-2): 281 doi: 10.1365/s10337-009-1149-1
5
Shivakumar Chitturi, Geoffrey C Farrell. Hepatotoxic slimming aids and other herbal hepatotoxinsJournal of Gastroenterology and Hepatology 2008; 23(3): 366 doi: 10.1111/j.1440-1746.2008.05310.x
6
Guo-Dong Shan, Guo-Qiang Xu, Li-Hua Chen, Zhao-Ming Wang, En-Yun Jin, Feng-Ling Hu, You-Ming Li. Diffuse Liver Infiltration by Melanoma of Unknown Primary Origin: One Case Report and Literature ReviewInternal Medicine 2009; 48(24): 2093 doi: 10.2169/internalmedicine.48.2542
7
Xiaoqi Jing, Jiaqi Zhang, Zhenlin Huang, Yuchen Sheng, Lili Ji. The involvement of Nrf2 antioxidant signalling pathway in the protection of monocrotaline-induced hepatic sinusoidal obstruction syndrome in rats by (+)-catechin hydrateFree Radical Research 2018; 52(4): 402 doi: 10.1080/10715762.2018.1437914
8
Arturo Anadón, María Rosa Martínez-Larrañaga, Irma Ares, María Aránzazu Martínez. Nutraceuticals2016; : 855 doi: 10.1016/B978-0-12-802147-7.00060-7
9
Zhiyong Zheng, Liang Shi, Yuchen Sheng, Jiaqi Zhang, Bin Lu, Lili Ji. Chlorogenic acid suppresses monocrotaline-induced sinusoidal obstruction syndrome: The potential contribution of NFκB, Egr1, Nrf2, MAPKs and PI3K signalsEnvironmental Toxicology and Pharmacology 2016; 46: 80 doi: 10.1016/j.etap.2016.07.002
10
Weiwei Li, Kai Wang, Ge Lin, Ying Peng, Jiang Zheng. Lysine Adduction by Reactive Metabolite(s) of MonocrotalineChemical Research in Toxicology 2016; 29(3): 333 doi: 10.1021/acs.chemrestox.5b00488
11
Anindita Ghosh, Suvra Mandal, Avijit Banerji, Manoj Kar, Kalyan Hazra, Julie Banerji. A Novel Biflavonyloxymethane from Pongamia Pinnata and its Radical Quenching ActivityNatural Product Communications 2011; 6(5): 1934578X1100600 doi: 10.1177/1934578X1100600511
12
Nora Anderson, Jürgen Borlak. Hepatobiliary Events in Migraine Therapy with Herbs—The Case of Petadolex, A Petasites Hybridus ExtractJournal of Clinical Medicine 2019; 8(5): 652 doi: 10.3390/jcm8050652
13
S.B. Yee, R.A. Roth. Comprehensive Toxicology2010; : 595 doi: 10.1016/B978-0-08-046884-6.01026-5
14
Eun Yee Jie, Nornita Sham Atong, Woo Seok Ahn, Myung Suk Ahn, Byung Hwan Min, Saleh Kadzimin, Suk Weon Kim. High-frequency plant regeneration from embryogenic cell suspension cultures of Gynura procumbensPlant Biotechnology Reports 2019; 13(1): 27 doi: 10.1007/s11816-018-0507-6
15
Jiaqi Zhang, Yuchen Sheng, Liang Shi, Zhiyong Zheng, Minwei Chen, Bin Lu, Lili Ji. Quercetin and baicalein suppress monocrotaline-induced hepatic sinusoidal obstruction syndrome in ratsEuropean Journal of Pharmacology 2017; 795: 160 doi: 10.1016/j.ejphar.2016.12.015
16
Jiang Ma, Jianqing Ruan, Xinmeng Chen, Dongping Li, Sheng Yao, Peter P. Fu, Yang Ye, Hong Gao, Jiyao Wang, Ge Lin. Pyrrole–Hemoglobin Adducts, a More Feasible Potential Biomarker of Pyrrolizidine Alkaloid ExposureChemical Research in Toxicology 2019; 32(6): 1027 doi: 10.1021/acs.chemrestox.8b00369
17
Weiqian Wang, Xiao Yang, Yan Chen, Xuanling Ye, Kaiyuan Jiang, Aizhen Xiong, Li Yang, Zhengtao Wang. Seneciphylline, a main pyrrolizidine alkaloid in Gynura japonica, induces hepatotoxicity in mice and primary hepatocytes via activating mitochondria‐mediated apoptosisJournal of Applied Toxicology 2020; 40(11): 1534 doi: 10.1002/jat.4004
18
Tong-Yin Zhu, Guan-Hui Zhou, Xin-Hua Chen, Xiao-Dong Teng, Jun-Hui Sun. Hepatic veno-occlusive disease may be a rare characteristic of hepatic involvement in systemic amyloidosis: case report and literature reviewJournal of International Medical Research 2020; 48(2): 030006052090485 doi: 10.1177/0300060520904857
19
Yan Hong Li, Winnie Lai Ting Kan, Na Li, Ge Lin. Assessment of pyrrolizidine alkaloid-induced toxicity in an in vitro screening modelJournal of Ethnopharmacology 2013; 150(2): 560 doi: 10.1016/j.jep.2013.09.010
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Naseem Ahmad, Nigar Fatima, Iqbal Ahmad, Mohammad Anis. Effect of PGRs in adventitious root culture in vitro: present scenario and future prospectsRendiconti Lincei 2015; 26(3): 307 doi: 10.1007/s12210-015-0445-y
21
Lianxiang Fang, Aizhen Xiong, Xiao Yang, Wenzhi Cheng, Li Yang, Zhengtao Wang. Mass-spectrometry-directed analysis and purification of pyrrolizidine alkaloidcis/transisomers inGynura japonicaJournal of Separation Science 2014; 37(15): 2032 doi: 10.1002/jssc.201400314
22
Yan Chen, Fen Xiong, Weiqian Wang, Kaiyuan Jiang, Xuanling Ye, Gang Deng, Changhong Wang, Li Yang, Aizhen Xiong, Zhengtao Wang. The long persistence of pyrrolizidine alkaloid-derived pyrrole-protein adducts in vivo: Kinetic study following multiple exposures of a pyrrolizidine alkaloid containing extract of Gynura japonicaToxicology Letters 2020; 323: 41 doi: 10.1016/j.toxlet.2020.01.021
23
Jing‐yu Yang, Li‐hui Wang. Traditional Herbal Medicine Research Methods2011; : 303 doi: 10.1002/9780470921340.ch7
24
Joanne Chiu, Thomas Yau, Richard J. Epstein. Complications of traditional Chinese/herbal medicines (TCM)—a guide for perplexed oncologists and other cancer caregiversSupportive Care in Cancer 2009; 17(3): 231 doi: 10.1007/s00520-008-0526-x
25
Sebastian Schramm, Nikolai Köhler, Wilfried Rozhon. Pyrrolizidine Alkaloids: Biosynthesis, Biological Activities and Occurrence in Crop PlantsMolecules 2019; 24(3): 498 doi: 10.3390/molecules24030498
26
Mohd Zuwairi Saiman, Natali Rianika Mustafa, Anna Elisabeth Schulte, Robert Verpoorte, Young Hae Choi. Induction, characterization, and NMR-based metabolic profiling of adventitious root cultures from leaf explants of Gynura procumbensPlant Cell, Tissue and Organ Culture (PCTOC) 2012; 109(3): 465 doi: 10.1007/s11240-011-0111-8
27
Aizhen Xiong, Fan Yang, Lianxiang Fang, Li Yang, Yuqi He, Yvonne Yu-Jui Wan, Ying Xu, Meng Qi, Xiuli Wang, Kate Yu, Karl Wah-Keung Tsim, Zhengtao Wang. Metabolomic and Genomic Evidence for Compromised Bile Acid Homeostasis by Senecionine, a Hepatotoxic Pyrrolizidine AlkaloidChemical Research in Toxicology 2014; 27(5): 775 doi: 10.1021/tx400451q
28
Zhenlin Huang, Yuchen Sheng, Minwei Chen, Zhanxia Hao, Feifei Hu, Lili Ji. Liquiritigenin and liquiritin alleviated MCT-induced HSOS by activating Nrf2 antioxidative defense systemToxicology and Applied Pharmacology 2018; 355: 18 doi: 10.1016/j.taap.2018.06.014
29
Fang Zhang, Yue Zhou, Xiao Yang, Ai-zhen Xiong, Zheng-tao Wang, Li Yang. Gynura Rhizoma containing pyrrolizidine alkaloids induces the hepatic sinusoidal obstruction syndrome in mice via upregulating fibrosis-related factorsActa Pharmacologica Sinica 2019; 40(6): 781 doi: 10.1038/s41401-018-0155-y
30
Zhangting Wang, Jiang Ma, Sheng Yao, Yisheng He, Kai-Kei Miu, Qingsu Xia, Peter P. Fu, Yang Ye, Ge Lin. Liquorice Extract and 18β-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic ActivationFrontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.850859
31
Doris B. Strader, Victor J. Navarro, Leonard B. Seeff. Zakim and Boyer's Hepatology2012; : 462 doi: 10.1016/B978-1-4377-0881-3.00026-7
32
Zhenlin Huang, Minwei Chen, Jiaqi Zhang, Yuchen Sheng, Lili Ji. Integrative analysis of hepatic microRNA and mRNA to identify potential biological pathways associated with monocrotaline-induced liver injury in miceToxicology and Applied Pharmacology 2017; 333: 35 doi: 10.1016/j.taap.2017.08.007
33
Meng-xiao Feng, Yan Shen, Yuan-qiang Lu. Clinical characteristics and outcomes of patients with hepatic veno-occlusive disease induced by Gynura segetum: A retrospective studyJournal of Integrative Medicine 2020; 18(5): 434 doi: 10.1016/j.joim.2020.07.006
34
Dominique Larrey, Stéphanie Faure. Herbal medicine hepatotoxicity: A new step with development of specific biomarkersJournal of Hepatology 2011; 54(4): 599 doi: 10.1016/j.jhep.2010.12.003
35
Scientific Opinion on Pyrrolizidine alkaloids in food and feedEFSA Journal 2011; 9(11) doi: 10.2903/j.efsa.2011.2406
36
Lin Zhu, Jian-Qing Ruan, Na Li, Peter P. Fu, Yang Ye, Ge Lin. A novel ultra-performance liquid chromatography hyphenated with quadrupole time of flight mass spectrometry method for rapid estimation of total toxic retronecine-type of pyrrolizidine alkaloids in herbs without requiring corresponding standardsFood Chemistry 2016; 194: 1320 doi: 10.1016/j.foodchem.2014.11.093
37
Hongyi Zhu, Yi Chu, Jirong Huo, Zhe Chen, Li Yang. Effect of prednisone on transforming growth factor‐β1, connective tissue growth factor, nuclear factor‐κBp65 and tumor necrosis factor‐α expression in a murine model of hepatic sinusoidal obstruction syndrome induced by Gynura segetumHepatology Research 2011; 41(8): 795 doi: 10.1111/j.1872-034X.2011.00830.x
38
Latif Ahmad, Yi He, Andrew J. Semotiuk, Quan-Ru Liu, Jia-Chen Hao. Survey of pyrrolizidine alkaloids in the tribe Lithospermeae (Boraginaceae) from Pan-Himalaya and their chemotaxonomic significanceBiochemical Systematics and Ecology 2018; 81: 49 doi: 10.1016/j.bse.2018.09.002
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Junchi Wang, Meng Zhang, Lihua Chen, Yue Qiao, Siqi Ma, Dian Sun, Jianyong Si, Yonghong Liao. Determination of Toxic Pyrrolizidine Alkaloids in Traditional Chinese Herbal Medicines by UPLC-MS/MS and Accompanying Risk Assessment for Human HealthMolecules 2021; 26(6): 1648 doi: 10.3390/molecules26061648
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Chen Li, Xue-Song Liang, Cheng-Zhong Li. Sinusoidal obstruction syndrome associated with the ingestion of gynura rootClinical Toxicology 2010; 48(9): 962 doi: 10.3109/15563650.2010.527851
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Weiwei Li, Ting Cheng, Tingting Jiang, Mengyue Zhou, Bowen Gong, Guode Zhao, Jing Li, Rong Tan, Xiaojing Yang, Kandarp Joshi, Ying Peng, Maosheng Cheng, Ting Liu, Dan Ohtan Wang, Jiang Zheng. Hepatic RNA adduction derived from metabolic activation of retrorsine in vitro and in vivoChemico-Biological Interactions 2022; 365: 110047 doi: 10.1016/j.cbi.2022.110047
42
Jianqing Ruan, Hong Gao, Na Li, Junyi Xue, Jie Chen, Changqiang Ke, Yang Ye, Peter Pi-Cheng Fu, Jiang Zheng, Jiyao Wang, Ge Lin. Blood Pyrrole-Protein Adducts—A Biomarker of Pyrrolizidine Alkaloid-Induced Liver Injury in HumansJournal of Environmental Science and Health, Part C 2015; 33(4): 404 doi: 10.1080/10590501.2015.1096882
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Mengbi Yang, Jianqing Ruan, Hong Gao, Na Li, Jiang Ma, Junyi Xue, Yang Ye, Peter Pi-Cheng Fu, Jiyao Wang, Ge Lin. First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humansArchives of Toxicology 2017; 91(12): 3913 doi: 10.1007/s00204-017-2013-y
44
Xinmeng Chen, Jiang Ma, Yisheng He, Junyi Xue, Zijing Song, Qihe Xu, Ge Lin. Characterization of liver injury induced by a pyrrolizidine alkaloid in ratsPhytomedicine 2021; 89: 153595 doi: 10.1016/j.phymed.2021.153595
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Hong GAO, Na LI, Ji Yao WANG, Shun Cai ZHANG, Ge LIN. Definitive diagnosis of hepatic sinusoidal obstruction syndrome induced by pyrrolizidine alkaloidsJournal of Digestive Diseases 2012; 13(1): 33 doi: 10.1111/j.1751-2980.2011.00552.x
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Aizhen Xiong, Lianxiang Fang, Xiao Yang, Fan Yang, Meng Qi, Hong Kang, Li Yang, Karl Wah-Keung Tsim, Zhengtao Wang. An application of target profiling analyses in the hepatotoxicity assessment of herbal medicines: comparative characteristic fingerprint and bile acid profiling of Senecio vulgaris L. and Senecio scandens Buch.-HamAnalytical and Bioanalytical Chemistry 2014; 406(29): 7715 doi: 10.1007/s00216-014-8175-z
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Arturo Anadón, Irma Ares, María-Rosa Martínez-Larrañaga, María-Aránzazu Martínez. Nutraceuticals2021; : 1175 doi: 10.1016/B978-0-12-821038-3.00070-7
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Jiang Ma, Qingsu Xia, Peter P. Fu, Ge Lin. Pyrrole-protein adducts – A biomarker of pyrrolizidine alkaloid-induced hepatotoxicityJournal of Food and Drug Analysis 2018; 26(3): 965 doi: 10.1016/j.jfda.2018.05.005
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Latif Ahmad, Yi He, Jia-Chen Hao, Andrew Semotiuk, Quan-Ru Liu, Paras Mazari. Toxic pyrrolizidine alkaloids provide a warning sign to overuse of the ethnomedicine Arnebia benthamiiJournal of Ethnopharmacology 2018; 210: 88 doi: 10.1016/j.jep.2017.08.009
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Chunyan Peng, Xiaofeng Zhang, Feng Zhang, Longgen Liu, Youlin Shao, Xiaoxing Xiang, Wei Zhang, Jiangqiang Xiao, Yi Wang, Bin Zhang, Qin Yin, Yuhu Song, Zhe Mo, Xiaoping Zou, Ming Zhang, Yuzheng Zhuge. Clinical efficacy and safety of anticoagulation therapy for Pyrrolizidine alkaloids-induced hepatic sinusoidal obstruction syndrome: a retrospective multicenter cohort studyEuropean Journal of Gastroenterology & Hepatology 2020; 32(9): 1168 doi: 10.1097/MEG.0000000000001630
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Dominique Larrey, Jose Ursic‐Bedoya, Lucy Meunier. Schiff's Diseases of the Liver2017; : 740 doi: 10.1002/9781119251316.ch27
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Ting Cheng, Weiwei Li, Xiaojing Yang, Huali Wang, Fan Zhang, Na Li, Ge Lin, Jiang Zheng. Antibody-based detection of lysine modification of hepatic protein in mice treated with retrorsineJournal of Environmental Science and Health, Part C 2020; 38(4): 315 doi: 10.1080/26896583.2020.1832411
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Marianna Martinello, Alice Borin, Roberto Stella, Davide Bovo, Giancarlo Biancotto, Albino Gallina, Franco Mutinelli. Development and validation of a QuEChERS method coupled to liquid chromatography and high resolution mass spectrometry to determine pyrrolizidine and tropane alkaloids in honeyFood Chemistry 2017; 234: 295 doi: 10.1016/j.foodchem.2017.04.186
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Ge Lin, Ji Yao Wang, Na Li, Mi Li, Hong Gao, Yuan Ji, Fan Zhang, Huali Wang, Yan Zhou, Yang Ye, Hong Xi Xu, Jiang Zheng. Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetumJournal of Hepatology 2011; 54(4): 666 doi: 10.1016/j.jhep.2010.07.031
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M. James Lopez, Jacob L. Bilhartz. Diseases of the Liver in Children2014; : 371 doi: 10.1007/978-1-4614-9005-0_19
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Zhenlin Huang, Minwei Chen, Mengjuan Wei, Bin Lu, Xiaojun Wu, Zhengtao Wang, Lili Ji. Liver Inflammatory Injury Initiated by DAMPs-TLR4-MyD88/TRIF-NFκB Signaling Pathway Is Involved in Monocrotaline-Induced HSOSToxicological Sciences 2019; 172(2): 385 doi: 10.1093/toxsci/kfz193
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Ara Tachjian, Viqar Maria, Arshad Jahangir. Use of Herbal Products and Potential Interactions in Patients With Cardiovascular DiseasesJournal of the American College of Cardiology 2010; 55(6): 515 doi: 10.1016/j.jacc.2009.07.074
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Jean-François Picron, Mélanie Herman, Els Van Hoeck, Séverine Goscinny. Monitoring of pyrrolizidine alkaloids in beehive products and derivatives on the Belgian marketEnvironmental Science and Pollution Research 2020; 27(6): 5693 doi: 10.1007/s11356-019-04499-2
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S.B. Yee, R.A. Roth. Comprehensive Toxicology2018; : 522 doi: 10.1016/B978-0-12-801238-3.02114-0
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Panpan Cen, Jiexia Ding, Jie Jin. Hepatic sinusoidal obstruction syndrome caused by the ingestion of Gynura segetum in a patient with alcoholic cirrhosis: a case reportJournal of International Medical Research 2021; 49(4): 030006052098064 doi: 10.1177/0300060520980649
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O. A. Demidova, V. V. Arkhipov, M. V. Zhuravleva, T. A. Alexandrova, A. A. Alexandrov. Safety of Herbal Medicines: Clinical and Pharmacological AspectsSafety and Risk of Pharmacotherapy 2020; 8(4): 165 doi: 10.30895/2312-7821-2020-8-4-165-177
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Raúl J. Andrade, Guruprasad P. Aithal, Einar S. Björnsson, Neil Kaplowitz, Gerd A. Kullak-Ublick, Dominique Larrey, Tom H. Karlsen. EASL Clinical Practice Guidelines: Drug-induced liver injuryJournal of Hepatology 2019; 70(6): 1222 doi: 10.1016/j.jhep.2019.02.014
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Nisarat Siriwatanametanon, Michael Heinrich. The Thai Medicinal Plant Gynura Pseudochina var. hispida: Chemical Composition and in vitro NF-κB Inhibitory ActivityNatural Product Communications 2011; 6(5): 1934578X1100600 doi: 10.1177/1934578X1100600512
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Julia Buchmueller, Anne-Margarethe Enge, Antonia Peters, Johanna Ebmeyer, Jan-Heiner Küpper, Bernd Schäfer, Albert Braeuning, Stefanie Hessel-Pras. The chemical structure impairs the intensity of genotoxic effects promoted by 1,2-unsaturated pyrrolizidine alkaloids in vitroFood and Chemical Toxicology 2022; 164: 113049 doi: 10.1016/j.fct.2022.113049
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Yan-yun Shu, Li-lin Hu, Ling Yang, Hui-kuan Chu, Jin Ye, Yu Jin. Rifaximin Prevents Intestinal Barrier Dysfunction and Alleviates Liver Injury in MCT-induced HSOS MiceCurrent Medical Science 2023; 43(6): 1183 doi: 10.1007/s11596-023-2801-y
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Jun-Hong Liu, Han Yang, Ling Zhang, Xing-Rong Peng, Zhen-Jie Li, Mei-Ying He, Luo-Sheng Wan, Zhong-Rong Li, Lin Zhou, Zhi-Hua Liu, Ming-Hua Qiu. Pyrrolizidine alkaloids from the seeds of Scleropyrum wallichianumJournal of Asian Natural Products Research 2021; 23(5): 407 doi: 10.1080/10286020.2020.1740919
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Xueyong Qi, Bin Wu, Yiyu Cheng, Haibin Qu. Simultaneous characterization of pyrrolizidine alkaloids and N‐oxides in Gynura segetum by liquid chromatography/ion trap mass spectrometryRapid Communications in Mass Spectrometry 2009; 23(2): 291 doi: 10.1002/rcm.3862
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Ziyi Sun, Jianmei Kang, Yongchang Zhang. Hepatic veno-occlusive disease related to Gynura segetumMedicine 2018; 97(17): e0552 doi: 10.1097/MD.0000000000010552