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World J Obstet Gynecol. Feb 10, 2016; 5(1): 78-86
Published online Feb 10, 2016. doi: 10.5317/wjog.v5.i1.78
Evaluation of sentinel lymph nodes in vulvar, endometrial and cervical cancers
Jenna Emerson, Katina Robison
Jenna Emerson, Katina Robison, Program in Women’s Oncology, Department of Obstetrics and Gynecology, Women and Infants Hospital, Alpert Medical School, Brown University, Providence, RI 02905, United States
Author contributions: Emerson J was co-writer; Robison K was co-writer and edited review.
Conflict-of-interest statement: The authors had no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Katina Robison, MD, Program in Women’s Oncology, Department of Obstetrics and Gynecology, WWomen and Infants Hospital, Alpert Medical School, Brown University, 101 Dudley Street, Providence, RI 02905, United States. krobison@wihri.org
Telephone: +1-401-2741100 Fax: +1-401-4537529
Received: July 3, 2015
Peer-review started: July 31, 2015
First decision: September 30, 2015
Revised: October 28, 2015
Accepted: November 23, 2015
Article in press: November 25, 2015
Published online: February 10, 2016
Core Tip

Core tip: In a specific population of women with vulvar cancer, sentinel lymph node (SLN) dissection is an effective and safe alternative to complete dissection. It can be offered as an alternative management strategy in these women. Sentinel node biopsy is also associated with an improved quality of life. Promising evidence supporting the utility of SLN dissection in endometrial and cervical cancer continues to emerge, and it may soon become a reasonable option for select patients. However, continued research and refinement of appropriate patient selection and long-term follow-up are necessary.