Editorial
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Mar 28, 2017; 9(3): 91-96
Published online Mar 28, 2017. doi: 10.4329/wjr.v9.i3.91
Laser ablation of liver tumors: An ancillary technique, or an alternative to radiofrequency and microwave?
Sergio Sartori, Francesca Di Vece, Francesca Ermili, Paola Tombesi
Sergio Sartori, Francesca Di Vece, Francesca Ermili, Paola Tombesi, Section of Interventional Ultrasound, St Anna Hospital, 44100 Ferrara, Italy
Author contributions: Sartori S, Di Vece F, Ermili F and Tombesi P contributed equally to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: The authors declare no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Sergio Sartori, MD, Section of Interventional Ultrasound, St Anna Hospital, via A. Moro 8, 44100 Ferrara, Italy. srs@unife.it
Telephone: +39-0532-239480 Fax: +39-0532-239613
Received: July 31, 2016
Peer-review started: August 2, 2016
First decision: September 28, 2016
Revised: December 23, 2016
Accepted: January 11, 2017
Article in press: January 14, 2017
Published online: March 28, 2017
Abstract

Radiofrequency ablation (RFA) is currently the most popular and used ablation modality for the treatment of non surgical patients with primary and secondary liver tumors, but in the last years microwave ablation (MWA) is being technically improved and widely rediscovered for clinical use. Laser thermal ablation (LTA) is by far less investigated and used than RFA and MWA, but the available data on its effectiveness and safety are quite good and comparable to those of RFA and MWA. All the three hyperthermia-based ablative techniques, when performed by skilled operators, can successfully treat all liver tumors eligible for thermal ablation, and to date in most centers of interventional oncology or interventional radiology the choice of the technique usually depends on the physician’s preference and experience, or technical availability. However, RFA, MWA, and LTA have peculiar advantages and limitations that can make each of them more suitable than the other ones to treat patients and tumors with different characteristics. When all the three thermal ablation techniques are available, the choice among RFA, MWA, and LTA should be guided by their advantages and disadvantages, number, size, and location of the liver nodules, and cost-saving considerations, in order to give patients the best treatment option.

Keywords: Radiofrequency ablation, Liver neoplasm, Laser ablation, Microwave ablation, Hepatocellular carcinoma, Liver metastases

Core tip: Radiofrequency ablation, microwave ablation, and laser thermal ablation, when performed by skilled operators, can successfully treat all liver tumors eligible for thermal ablation. However, each of them has peculiar advantages and limitations that can make one technique more suitable than the other ones to treat patients and tumors with different characteristics. When all the three techniques are available, the choice should be guided by their advantages and disadvantages, number, size and location of the liver nodules, and cost-saving considerations, in order to give patients the best treatment option.