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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Apr 15, 2016; 8(4): 341-350
Published online Apr 15, 2016. doi: 10.4251/wjgo.v8.i4.341
Published online Apr 15, 2016. doi: 10.4251/wjgo.v8.i4.341
Helicobacter pylori associated Asian enigma: Does diet deserve distinction?
Syed Faisal Zaidi, Department of Basic Medical Sciences, College of Medicine, King Saud bin Abdulaziz University of Health Sciences, Jeddah 21423, Saudi Arabia
Author contributions: Zaidi SF wrote this manuscript.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Syed Faisal Zaidi, PhD, Assistant Professor, Department of Basic Medical Sciences, College of Medicine, King Saud bin Abdulaziz University of Health Sciences, Jeddah 21423, Saudi Arabia. sfaisalhz@gmail.com
Telephone: +966-9-22245778 Fax: +966-9-20008668
Received: August 28, 2015
Peer-review started: September 16, 2015
First decision: October 21, 2015
Revised: November 23, 2015
Accepted: January 21, 2016
Article in press: January 22, 2016
Published online: April 15, 2016
Peer-review started: September 16, 2015
First decision: October 21, 2015
Revised: November 23, 2015
Accepted: January 21, 2016
Article in press: January 22, 2016
Published online: April 15, 2016
Core Tip
Core tip: Despite the established etiological role of Helicobacter pylori (H. pylori), its actual distribution and association with related diseases is controversial, especially among Asian countries, a phenomenon termed as Asian enigma. This is judged by genetic variability of the infecting H. pylori strains, diversity in the host genetic background, and environmental factors such as diet. Amongst these, the dietary factor was not given much attention. In this review, dietary components are focused in detail with respect to H. pylori-associated enigma with a specific emphasis and comparison of dietary ingredients between Asian countries in order to critically evaluate its role in Asian enigma.