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World J Gastrointest Oncol. Feb 15, 2014; 6(2): 41-51
Published online Feb 15, 2014. doi: 10.4251/wjgo.v6.i2.41
Published online Feb 15, 2014. doi: 10.4251/wjgo.v6.i2.41
Mechanisms linking dietary fiber, gut microbiota and colon cancer prevention
Huawei Zeng, United States Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND 58203, United States
Darina L Lazarova, Michael Bordonaro, Department of Basic Sciences, The Commonwealth Medical College, Scranton, PA 18509, United States
Author contributions: Zeng H conceived the topic, contributed to the writing and revising, and provided overall design and execution of the manuscript; Lazarova DL and Bordonaro M contributed to the writing and revising the manuscript.
Supported by The United States Department of Agriculture
Correspondence to: Huawei Zeng, PhD, United States Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, 2420 2nd Ave. North, Grand Forks, ND 58203, United States. huawei.zeng@ars.usda.gov
Telephone: +1-701-7958465 Fax: +1-701-7958220
Received: November 25, 2013
Revised: December 27, 2013
Accepted: January 15, 2014
Published online: February 15, 2014
Revised: December 27, 2013
Accepted: January 15, 2014
Published online: February 15, 2014
Core Tip
Core tip: Dietary fiber modulates our health at nearly every level, and in every organ system, via complicated modes of action. This article reviews the mechanistic association of dietary fiber, gut microbiota and colon cancer prevention.