Published online Feb 15, 2016. doi: 10.4251/wjgo.v8.i2.231
Peer-review started: July 10, 2015
First decision: September 30, 2015
Revised: November 18, 2015
Accepted: December 7, 2015
Article in press: December 8, 2015
Published online: February 15, 2016
Neuroendocrine tumors of the gastrointestinal tract are rare neoplasms. Rectal neuroendocrine tumors consist approximately the 5%-14% of all neuroendocrine neoplasms in Europe. These tumors are diagnosed in relatively young patients, with a mean age at diagnosis of 56 years. Distant metastases from rectal neuroendocrine tumors are not very common. Herein we describe a case of a rectal neuroendocrine tumor which metastasized to the lung, mediastinum and orbit. This case underscores the importance of early identification and optimal management to improve patient’s prognosis. Therefore, the clinical significance of this case is the necessity of physicians’ awareness and education regarding neuroendocrine tumors’ diagnosis and management.
Core tip: Rectal neuroendocrine tumors consist approximately 5%-14% of all neuroendocrine neoplasms in Europe. Distant metastases from rectal neuroendocrine tumors are not very common. Herein we describe a case of a rectal neuroendocrine tumor with an uncommon natural history as well as a review of the literature. The present case underscores the importance of early identification and management of these tumors.