1 FILE NAME

(1) Name of a Main Document: Name with the Running title of your manuscript; (2) Name of images: Images are named as Figure 1, Figure 2, Figure 3 and so on in ascending order. It may also be submitted separately as Figure 1A, Figure 1B and so on if there is a group of figures.

2 PREPARATIONS BEFORE SUBMISSION

You can only upload one file that does not exceed 5 MB each time, including main document, images and tables. You must upload them separately or convert to a single PDF before uploading if the files exceed 5 MB. The sequence of uploaded files is as follows:

2 .1 Article scope: Clinical Practice or Basic Science

2 .2 Specialty Type:

Biliary Disorders
Clinical Practice
Enteric Neurosciences
Epithelial Transport
Esophageal/Gastric/Duodenal Disorders
Gastrointestinal Oncology
Growth and Development
Hormones and Receptors
Human and Cancer Genetics
Imaging and Advanced Technology
Immunology and Microbiology
Inflammatory Disorders
Intestinal Disorders
Liver Descriptors
Nutrition and Obesity
Pancreatic Disorders
Psychosocial or Behavioral Factors and Quality of Life

2 .3 Article Type：Editorial, Topic Highlights, Observation, Guidelines Basic Science, Guidelines Clinical Practice, Research Frontier, Review, Original Articles, Brief Articles, Case Report, Letters To The Editor, Book Reviews, Guidelines.

2 .4 Title：Your title may contain as many as 25 words, and can include special characters.

2 .5 Running Title: A short running title of less than 6 words should be provided.

2 .6 Keywords: Please list 5 key words for each manuscript.

2 .7 Abstract: Your abstract may contain as many as 480 words, and can include special characters.

2 .8 Cover Letter: Your cover letter may contain as many as 480 words, and can include special characters.

2 .9 Sponsors/Acknowledgments

2 .10 Invoice Address

International authors fill out the box in English.

Domestic authors fill out the box in Chinese.

2 .11 All Authors Consent: You must mark a checkbox on the button “All Authors Consent” as an affirmative response.

2 .12 Suggested Reviewers：You may not fill in your suggested reviewers using the textboxes below.

2 .13 Correspondence to (Name, Title, Department, Institution, Address, City, ZIP/Postal Code, Country, E-mail).

This person is the formal Corresponding Author as denoted on the title page of the manuscript.

International authors fill out the box in English.

Domestic authors fill out the box in Chinese.

2 .14 All authors names.

2 .15 Number of authors.

2 .16 All color, black and white images should be saved and supplied as TIFF, GIF, EPS, Power Point or high-quality JPEG files to a minimum of 300 dpi. Image: You can directly upload the images less than 5 MB. But the images that exceed 5 MB must be converted in PDF or be uploaded as several separate files.

2 .17 Manuscript: Its contents should include title, running title, all authors names, affiliations, author contributions, supported by, correspondence to, telephone, fax, abstract (aim, methods, results, conclusion), key words, introduction, materials and methods, results, discussion, references, figure legends, and table.

3 UPLOAD FILES

Step 1: You will see the "Author Area" button after logging into http://www.wjgnet.com/1007-9327office/, click on the button " Submit New Manuscript". Select your Article scope and Specialty Type. Enter Total number of authors, your Title, Running title, Keywords, Abstract, Cover Letter, Sponsors/Acknowledgments, Invoice Address and All Authors Consent into the appropriate boxes below. When you have finished, click "Save/ Continue."

Step 2: Enter all Authors' Information in the boxes below. If the author has a record in this system, enter their Email address above and click on the 'Lookup' button, their information will be automatically filled out.

Special Attention: Double-check that the formal Corresponding Author has been designated.

When you have finished, click on "Save / Continue."

Step 3: Enter Image files, Number of Manuscript Pages, Total Number of Figures, Number of Line Drawings and Graphs, Number of Black & White Figures, Number of Color Figures, Number of Tables, Word count, Abstract word count in the boxes below. One file that does not exceed 5 MB can be uploaded directly, but a file that exceeds 5 MB must be converted to a single PDF document or be uploaded as several separate files.

Special Attention: Please fill in “0” in the box “Image files” if all the images were contained in a single document; Please fill in “3” in the box “Image files” if three images and main document are separately uploaded. When you have finished, click "Save/ Continue."

Step 4: You upload the paper or images in the appropriate box.

When you have finished, click "Save /Continue."

Step 5: You can view Ms. No ,Title, Corresponding Author and all Authors of manuscript below the Confirmation Screen.

Very Important: After checking the manuscript information at this page, you MUST click 'SUBMIT' to complete your submission. The first author or the corresponding author will receive the autoreply of verification email.

If you have any other questions, please visit http://www.wjgnet.com/1007-9327office/ or email to wjg@wjgnet.com.

Thanks for your attention and submission!