Copyright
©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 21, 2014; 20(23): 7518-7522
Published online Jun 21, 2014. doi: 10.3748/wjg.v20.i23.7518
Published online Jun 21, 2014. doi: 10.3748/wjg.v20.i23.7518
Cronkhite-Canada syndrome: Report of six cases and review of literature
Xiao-Heng Wen, Lan Wang, Jia-Ming Qian, Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
Yu-Xuan Wang, Department of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA 30322, United States
Author contributions: Wen XH and Qian JM designed the study; Wen XH and Wang L collected the patient’s clinical data, analyzed the data and wrote the paper; Wang YX and Qian JM revised the paper.
Correspondence to: Jia-Ming Qian, Director, Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1, Shuai Fu Yuan, Beijing 100730, China. qianjiaming1957@126.com
Telephone: +86-10-65295019 Fax: +86-10-65295019s
Received: January 14, 2014
Revised: February 22, 2014
Accepted: April 8, 2014
Published online: June 21, 2014
Revised: February 22, 2014
Accepted: April 8, 2014
Published online: June 21, 2014
Core Tip
Core tip: Cronkhite-Canada syndrome (CCS) is a rare noncongenital gastrointestinal polyposis syndrome, characterized by skin hyperpigmentation, hair loss and nail atrophy, associated with high morbidity. This case report summarizes the characteristics of six CCS patients, and reviews the literature. Comprehensive treatment led by corticosteroids can improve prognosis, and long-term follow-up is necessary.