Topic Highlight
Copyright ©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Mar 7, 2013; 19(9): 1354-1358
Published online Mar 7, 2013. doi: 10.3748/wjg.v19.i9.1354
Vaccines and recommendations for their use in inflammatory bowel disease
María Dolores Sánchez-Tembleque, Carmen Corella, Jose L Pérez-Calle
María Dolores Sánchez-Tembleque, Carmen Corella, Gastroenterology Department, University Hospital of Guadalajara, 19002 Guadalajara, Spain
Jose L Pérez-Calle, Gastroenterology Department, University Hospital Fundación Alcorcón, 28922 Madrid, Spain
Author contributions: Sánchez-Tembleque MD, Corella C, Pérez-Calle JL contributed equally to this work; all authors have approved the final version of the manuscript.
Correspondence to: Dr. María Dolores Sánchez-Tembleque, Gastroenterology Department, University Hospital of Guadalajara, Av. Donantes de sangre sn, 19002 Guadalajara, Spain. loladig@hotmail.com
Telephone: +34-94-9209200 Fax: +34-94-9209259
Received: May 29, 2012
Revised: August 21, 2012
Accepted: September 19, 2012
Published online: March 7, 2013
Abstract

The patient with inflammatory bowel disease will be predisposed to numerous infections due their immune status. It is therefore important to understand the immune and serologic status at diagnosis and to put the patient into an adapted vaccination program. This program would be applied differently according to two patient groups: the immunocompromised and the non-immunocom-promised. In general, the first group would avoid the use of live-virus vaccines, and in all cases, inflammatory bowel disease treatment would take precedence over vaccine risk. It is important to individualize vaccination schedules according to the type of patient, the treatment used and the disease pattern.In addition, patient with inflammatory bowel disease should be considered for the following vaccines: varicella vaccine, human papilloma virus, influenza, pneumococcal polysaccharide vaccine and hepatitis B vaccine.

Keywords: Vaccines, Inflammatory bowel disease, Crohn’s disease, Ulcerative colitis, Immunocompromised