Case Report
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World J Gastroenterol. Apr 21, 2010; 16(15): 1924-1927
Published online Apr 21, 2010. doi: 10.3748/wjg.v16.i15.1924
Cystic fibrosis and Crohn’s disease: Successful treatment and long term remission with infliximab
Francesca Vincenzi, Barbara Bizzarri, Alessia Ghiselli, Nicola de’ Angelis, Fabiola Fornaroli, Gian Luigi de’ Angelis
Francesca Vincenzi, Barbara Bizzarri, Alessia Ghiselli, Fabiola Fornaroli, Gian Luigi de’ Angelis, Gastroenterology and Endoscopy Unit, University of Parma, via Gramsci 14, 43100 Parma, Italy
Nicola de’ Angelis, Digestive Surgery, University of Pisa, via Roma 5, 56126 Pisa, Italy
Author contributions: Vincenzi F and Bizzarri B contributed equally to writing the paper; de’ Angelis GL designed the project; Ghiselli A, de’ Angelis N and Fornaroli F collected the data.
Correspondence to: Gian Luigi de’ Angelis, Professor, Gastroenterology and Endoscopy Unit, University of Parma, via Gramsci 14, 43100 Parma, Italy. gianluigi.deangelis@unipr.it
Telephone: +39-521-702204 Fax: +39-521-702204
Received: December 22, 2009
Revised: January 13, 2010
Accepted: January 20, 2010
Published online: April 21, 2010
Abstract

The association of cystic fibrosis and Crohn’s disease (CD) is well known, but to date, there are very few cases in the literature of patients suffering from mucoviscidosis who have required treatment with infliximab. We report the case of a 23-year-old patient suffering from cystic fibrosis and severe CD treated successfully with infliximab without any infective complications or worsening of the pulmonary disease and with a long term (2 years) complete remission.

Keywords: Cystic fibrosis, Crohn’s disease, Infliximab